Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Helen E McNeil"'
Autor:
R Christopher D Furniss, Nikol Kaderabkova, Declan Barker, Patricia Bernal, Evgenia Maslova, Amanda AA Antwi, Helen E McNeil, Hannah L Pugh, Laurent Dortet, Jessica MA Blair, Gerald Larrouy-Maumus, Ronan R McCarthy, Diego Gonzalez, Despoina AI Mavridou
Publikováno v:
eLife, Vol 11 (2022)
Antimicrobial resistance in Gram-negative bacteria is one of the greatest threats to global health. New antibacterial strategies are urgently needed, and the development of antibiotic adjuvants that either neutralize resistance proteins or compromise
Externí odkaz:
https://doaj.org/article/ef99dec094a54ce9adaa86f09bb26e0b
Autor:
Emily E. Whittle, Helen E. McNeil, Eleftheria Trampari, Mark Webber, Tim W. Overton, Jessica M. A. Blair
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
This study shows that efflux is important for maintaining low intracellular accumulation only in actively growing cells and that envelope permeability is the predominant factor in stationary-phase cells. This conclusion means that (i) antibiotics wit
Externí odkaz:
https://doaj.org/article/e7078d590ca34faf877a261e8fd24c0f
Autor:
Jessica M A Blair, Pauline Siasat, Helen E McNeil, Abigail Colclough, Vito Ricci, Amelia J Lawler, Hind Abdalaal, Michelle M C Buckner, Alison Baylay, Stephen J Busby, Laura J V Piddock
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:133-140
Background Resistance nodulation division (RND) family efflux pumps, including the major pump AcrAB-TolC, are important mediators of intrinsic and evolved antibiotic resistance. Expression of these pumps is carefully controlled by a network of regula
Publikováno v:
Bulletin of Mathematical Biology. 84
Bacteria have developed resistance to antibiotics by various mechanisms, notable amongst these is the use of permeation barriers and the expulsion of antibiotics via efflux pumps. The resistance-nodulation-division (RND) family of efflux pumps is fou
Autor:
Nikol Kaderabkova, R Christopher D Furniss, Declan Barker, Patricia Bernal, Evgenia Maslova, Amanda AA Antwi, Helen E McNeil, Hannah L Pugh, Laurent Dortet, Jessica MA Blair, Gerald Larrouy-Maumus, Ronan R McCarthy, Diego Gonzalez, Despoina AI Mavridou
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
instname
Antimicrobial resistance in Gram-negative bacteria is one of the greatest threats to global health. New antibacterial strategies are urgently needed, and the development of antibiotic adjuvants that either neutralize resistance proteins or compromise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38067a7cb4dcf6e89ab421e425ab1838
Autor:
Tim W. Overton, Eleftheria Trampari, Emily E Whittle, Mark A. Webber, Helen E McNeil, Jessica M A Blair
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
mBio
mBio
For antibiotics with intracellular targets, effective treatment of bacterial infections requires the drug to accumulate to a high concentration inside cells. Bacteria produce a complex cell envelope and possess drug export efflux pumps to limit drug
Autor:
Nikol Kaderabkova, R Christopher D Furniss, Declan Barker, Patricia Bernal, Evgenia Maslova, Amanda AA Antwi, Helen E McNeil, Hannah L Pugh, Laurent Dortet, Jessica MA Blair, Gerald Larrouy-Maumus, Ronan R McCarthy, Diego Gonzalez, Despoina AI Mavridou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af7474d6603a6c9895a5861d9506f6e
https://doi.org/10.7554/elife.57974.sa2
https://doi.org/10.7554/elife.57974.sa2
Autor:
R. Christopher D. Furniss, Despoina A. I. Mavridou, Laurent Dortet, Ronan R. McCarthy, Declan Barker, Jessica M A Blair, Patricia Bernal, Amanda A.A. Antwi, Diego L. González, Evgenia Maslova, Nikol Kadeřábková, Helen E McNeil, Hannah L. Pugh, Gerald Larrouy-Maumus
Antimicrobial resistance in Gram-negative bacteria is one of the greatest threats to global health. New antibacterial strategies are urgently needed, and the development of antibiotic adjuvants that either neutralize resistance proteins or compromise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::256ab06ad4dccb04f1e222ea511aa237
https://doi.org/10.1101/2021.08.27.457985
https://doi.org/10.1101/2021.08.27.457985
Autor:
Tim W. Overton, Helen E McNeil, Eleftheria Trampari, Mark A. Webber, Blair Jma, Emily E Whittle
For antibiotics with intracellular targets, effective treatment of bacterial infections requires the drug to accumulate to a high concentration inside cells. Bacteria produce a complex cell envelope and possess drug-export efflux pumps to limit drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c619e3f8c2009049d6d38522cdb0683
https://doi.org/10.1101/2021.05.11.443560
https://doi.org/10.1101/2021.05.11.443560
Autor:
Ilyas Alav, Elizabeth M Darby, Emily E Whittle, Helen E McNeil, Hannah L. Pugh, Simon Legood, Abigail Colclough, Jessica M A Blair
Publikováno v:
Future microbiology. 15
Rresistance-nodulation-division (RND) efflux pumps in Gram-negative bacteria remove multiple, structurally distinct classes of antimicrobials from inside bacterial cells therefore directly contributing to multidrug resistance. There is also emerging