Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Helen Dooner"'
Autor:
Alexander Oksche, Kevin J. Smith, Gaia Rizzo, Eugenii A. Rabiner, Helen Dooner, Yvonne Lewis, Gill Mundin, Carla Bennett
Publikováno v:
British journal of clinical pharmacologyREFERENCES. 88(4)
BACKGROUND AND PURPOSE Preclinical studies of MR309, a selective sigma1 receptor (σ1R) antagonist, support a potential role in treating neuropathic pain. We report two studies that provide insight into the pharmacokinetics (PK) and brain σ1R bindin
Autor:
Gill Mundin, Kevin Smith, John Strang, Rebecca McDonald, Ulrike Lorch, Björn Bosse, Jo Woodward, Helen Dooner
Publikováno v:
Addiction. 113:484-493
Background and Aims Take-home naloxone can prevent death from heroin/opioid overdose, but pre-provision is difficult because naloxone is usually given by injection. Non-injectable alternatives, including naloxone nasal sprays, are currently being dev
Autor:
Carla Bennett, Marisol Escriche, Sabine Mersmann, Kevin John Smith, Gregorio Encina, Mercedes Encabo, Helen Dooner, Gill Mundin, Ulrike Lorch
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives Co-Crystal of Tramadol-Celecoxib (CTC) is a first-in-class active pharmaceutical ingredient (API–API) co-crystal of rac-tramadol.HCl and celecoxib in a 1:1 molecular ratio (100 mg CTC: 44 mg rac-tramadol.HCl and 56 mg cele
Autor:
Rebecca, McDonald, Ulrike, Lorch, Jo, Woodward, Björn, Bosse, Helen, Dooner, Gill, Mundin, Kevin, Smith, John, Strang
Publikováno v:
Addiction (Abingdon, England). 113(3)
Take-home naloxone can prevent death from heroin/opioid overdose, but pre-provision is difficult because naloxone is usually given by injection. Non-injectable alternatives, including naloxone nasal sprays, are currently being developed. To be effect