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Akademický článek

Myeloid cell-specific ABCA1 deletion does not worsen insulin resistance in HF diet-induced or genetically obese mouse models[S]

Autor: Xuewei Zhu, Soonkyu Chung, Xin Bi, Chia-Chi Chuang, Amanda L. Brown, Mingxia Liu, Jeongmin Seo, Helen Cuffe, Abraham K. Gebre, Elena Boudyguina, John S. Parks

Publikováno v: Journal of Lipid Research, Vol 54, Iss 10, Pp 2708-2717 (2013)

Obesity-associated low-grade chronic inflammation plays an important role in the development of insulin resistance. The membrane lipid transporter ATP-binding cassette transporter A1 (ABCA1) promotes formation of nascent HDL particles. ABCA1 also dam

Externí odkaz: https://doaj.org/article/8e7eb044fee143e58882d545debd80fb

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Targeted Deletion of Adipocyte Abca1 (ATP-Binding Cassette Transporter A1) Impairs Diet-Induced Obesity

Autor: Chia Chi C. Key, Allison Weckerle, Mingxia Liu, John S. Parks, Susan K. Fried, Janet K. Sawyer, Helen Cuffe, Elena Boudyguina, Soonkyu Chung, Alexander Bashore

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 38:733-743

Objective— Adipose tissue cholesterol increases with adipocyte triglyceride content and size during development of obesity. However, how adipocyte cholesterol affects adipocyte function is poorly understood. The aim of this study was to evaluate th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78dd57199483747e20ee61f93fc9bb4f
https://doi.org/10.1161/atvbaha.117.309880

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Myeloid cell-specific ABCA1 deletion does not worsen insulin resistance in HF diet-induced or genetically obese mouse models[S]

Autor: Xin Bi, Helen Cuffe, Jeongmin Seo, Chia-Chi Chuang, Abraham K. Gebre, Mingxia Liu, Elena Boudyguina, Amanda L. Brown, Soonkyu Chung, John S. Parks, Xuewei Zhu

Publikováno v: Journal of Lipid Research, Vol 54, Iss 10, Pp 2708-2717 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1a4c82fa6f4dba321cab7c67de1104
http://www.sciencedirect.com/science/article/pii/S0022227520352974

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Dietary Cholesterol Promotes Adipocyte Hypertrophy and Adipose Tissue Inflammation in Visceral, But Not Subcutaneous, Fat in Monkeys

Autor: Helen Cuffe, Peter Tontonoz, Jung-Heun Ha, Stephanie M. Marshall, Allison L. McDaniel, Soonkyu Chung, Kylie Kavanagh, John S. Parks, Cynthia Hong, Ryan E. Temel

Objective— Excessive caloric intake is associated with obesity and adipose tissue dysfunction. However, the role of dietary cholesterol in this process is unknown. The aim of this study was to determine whether increasing dietary cholesterol intake

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec9620b00581f881e363ea734ba8d49
https://europepmc.org/articles/PMC4140949/

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Abstract 82: Macrophage Specific ABCA1 Deletion Does Not Worsen Insulin Resistance in High Fat Diet Induced or Genetic Obese Mouse Models

Autor: Xuewei Zhu, Xin Bi, Chia-Chi Chuang, Soonkyu Chung, Amanda L Brown, Helen Cuffe, Abraham K Gebre, Elena Boudyguina, John S Parks

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 33

Introduction Obesity associated low-grade, chronic inflammation underlies the pathogenesis of type 2 diabetes and insulin resistance. ATP-binding cassette transporter A1 (ABCA1), a membrane lipid transporter, forms nascent HDL particles by effluxing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::895e368a69ea70a39e654026cdcf2e7d
https://doi.org/10.1161/atvb.33.suppl_1.a82

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