Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Helen C. Walkey"'
Autor:
Nicholas J. Thomas, Helen C. Walkey, Akaal Kaur, Shivani Misra, Nick S. Oliver, Kevin Colclough, Michael N. Weedon, Desmond G. Johnston, Andrew T. Hattersley, Kashyap A. Patel
Publikováno v:
Diabetologia. 66:310-320
Aims/hypothesis The reason for the observed lower rate of islet autoantibody positivity in clinician-diagnosed adult-onset vs childhood-onset type 1 diabetes is not known. We aimed to explore this by assessing the genetic risk of type 1 diabetes in a
Autor:
Helen C. Walkey, Desmond G. Johnston, Nick Oliver, William Hagopian, Akaal Kaur, Seth A. Sharp, John M Dennis, Shivani Misra, Kashyap A. Patel, Michael N. Weedon, Nicholas J. Thomas, Richard A. Oram
Publikováno v:
Diabetologia
Aims/hypothesis Among white European children developing type 1 diabetes, the otherwise common HLA haplotype DR15-DQ6 is rare, and highly protective. Adult-onset type 1 diabetes is now known to represent more overall cases than childhood onset, but i
Autor:
Shivani Misra, Jack Bowden, Kashyap Amratial Patel, Akaal Kaur, Desmond G. Johnston, Angus G. Jones, Helen C. Walkey, Timothy J. McDonald, Nick Oliver, Beverley M. Shields, Sian Louise Grace, Trevelyan J. McKinley
Publikováno v:
E4349
E4341
E4341
Positivity for islet autoantibodies is used for diagnosis of type 1 diabetes. However, the importance of the autoantibody level at diagnosis of type 1 diabetes is not clear. Here, we assessed the association of glutamate decarboxylase (GADA), islet a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d897bfaba7142f5eddcc840e85c77b08
http://hdl.handle.net/10044/1/104408
http://hdl.handle.net/10044/1/104408
Autor:
Nicholas J, Thomas, Helen C, Walkey, Akaal, Kaur, Shivani, Misra, Nick S, Oliver, Kevin, Colclough, Michael N, Weedon, Desmond G, Johnston, Andrew T, Hattersley, Kashyap A, Patel
Publikováno v:
Diabetologia.
The reason for the observed lower rate of islet autoantibody positivity in clinician-diagnosed adult-onset vs childhood-onset type 1 diabetes is not known. We aimed to explore this by assessing the genetic risk of type 1 diabetes in autoantibody-nega
Autor:
Shivani Misra, Nicholas J. Thomas, Helen C. Walkey, John M Dennis, Michael N. Weedon, Desmond G. Johnston, Richard A. Oram, Akaal Kaur, Nick Oliver, Kashyap A. Patel, Seth A. Sharp, William Hagopian
Publikováno v:
Diabetologia
Among white European children developing type 1 diabetes, the otherwise common HLA haplotype DR15-DQ6 is rare, and highly protective. Adult-onset type 1 diabetes is now known to represent more overall cases than childhood onset, but it is not known w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5ee25534a931d806d8af4f1360d729
https://europepmc.org/articles/PMC9172800/
https://europepmc.org/articles/PMC9172800/
Autor:
Nicholas J. Thomas, Akaal Kaur, Shivani Misra, Kevin Colclough, Desmond G. Johnston, Nick Oliver, Helen C. Walkey, Kashyap A. Patel, Andrew T. Hattersley, Michael N. Weedon
Objective: Islet autoantibodies at diagnosis are not well studied in older-adult onset (>30years) type 1 diabetes due to difficulties of accurate diagnosis. We used a type 1 diabetes genetic risk score (T1DGRS) to identify type 1 diabetes aiming to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3deb8e9500cae639147a9e1c3a845044
https://doi.org/10.1101/2021.03.22.21252507
https://doi.org/10.1101/2021.03.22.21252507
Autor:
Ian F. Godsland, Bravis, Akaal Kaur, Shivani Misra, Nick Oliver, Helen C. Walkey, Desmond G. Johnston
Publikováno v:
Diabetic Medicine. 34:71-74
Autor:
Alistair J K Williams, Desmond G. Johnston, Shivani Misra, Akaal Kaur, Ian F. Godsland, Helen C. Walkey, Nick Oliver
Publikováno v:
Diabetes. 68
Introduction: The phenotype of type 1 diabetes (T1D) has been explored mainly in white populations. People of non-white ethnicity are reportedly less likely to be antibody positive, but phenotypic differences are not well characterised. We investigat
Autor:
Andrew T. Hattersley, Alistair J K Williams, Desmond G. Johnston, Nick Oliver, Shivani Misra, Nicholas J. Thomas, Akaal Kaur, Kashyap A. Patel, Helen C. Walkey, Michael N. Weedon
Publikováno v:
Diabetes. 68
Aims: Accurate initial diagnosis of adult-onset type 1 diabetes (T1D) is important. We aimed to estimate the rate of misdiagnosis in clinically-diagnosed adult T1D. We also assessed the utility of Islet autoantibodies and presenting features to ident
Autor:
Ian F. Godsland, Anna Humphreys, Shivani Misra, Akaal Kaur, Nick Oliver, Helen C. Walkey, Desmond G. Johnston, Vassiliki Bravis
Publikováno v:
Diabetes research and clinical practice. 155
AIMS: People with recently-diagnosed type 1 diabetes mellitus (T1D) may undergo a transient period of glycaemic control with less exogenous insulin. Identification of predictors of this 'remission' could inform a better understanding of glycaemic con