Výsledky vyhledávání - "Helen C. Segal"

CHANGES IN THE CONTACT SYSTEM DURING ORTHOTOPIC LIVER TRANSPLANTATION WITH AND WITHOUT APROTININ

Autor: K. C. Tan, Beverley J. Hunt, Dennis Potter, John L. Francis, Simon Cottam, Helen C. Segal, Colin Beard

Publikováno v: Transplantation. 59:366-370

The main cause of nonsurgical bleeding during orthotopic liver transplantation has been attributed to be hyperfibrinolysis due to high plasma levels of tissue plasminogen activator. The aim of this study was to investigate contact activation and its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b56da9fb15c4e9fe3d7846e4a4a431ca
https://doi.org/10.1097/00007890-199502000-00011

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Loci associated with ischaemic stroke and its subtypes (SiGN) : A genome-wide association study

Autor: Sara L Pulit, Patrick F McArdle, Quenna Wong, Rainer Malik, Katrina Gwinn, Sefanja Achterberg, Ale Algra, Philippe Amouyel, Christopher D Anderson, Donna K Arnett, Ethem Murat Arsava, John Attia, Hakan Ay, Traci M Bartz, Thomas Battey, Oscar R Benavente, Steve Bevan, Alessandro Biffi, Joshua C Bis, Susan H Blanton, Giorgio B Boncoraglio, Robert D Brown, Annette I Burgess, Caty Carrera, Sherita N Chapman Smith, Daniel I Chasman, Ganesh Chauhan, Wei-Min Chen, Yu-Ching Cheng, Michael Chong, Lisa K Cloonan, John W Cole, Ioana Cotlarciuc, Carlos Cruchaga, Elisa Cuadrado-Godia, Tushar Dave, Jesse Dawson, Stéphanie Debette, Hossein Delavaran, Cameron A Dell, Martin Dichgans, Kimberly F Doheny, Chuanhui Dong, David J Duggan, Gunnar Engström, Michele K Evans, Xavier Estivill Pallejà, Jessica D Faul, Israel Fernández-Cadenas, Myriam Fornage, Philippe M Frossard, Karen Furie, Dale M Gamble, Christian Gieger, Anne-Katrin Giese, Eva Giralt-Steinhauer, Hector M González, An Goris, Solveig Gretarsdottir, Raji P Grewal, Ulrike Grittner, Stefan Gustafsson, Buhm Han, Graeme J Hankey, Laura Heitsch, Peter Higgins, Marc C Hochberg, Elizabeth Holliday, Jemma C Hopewell, Richard B Horenstein, George Howard, M Arfan Ikram, Andreea Ilinca, Erik Ingelsson, Marguerite R Irvin, Rebecca D Jackson, Christina Jern, Jordi Jiménez Conde, Julie A Johnson, Katarina Jood, Muhammad S Kahn, Robert Kaplan, L Jaap Kappelle, Sharon L R Kardia, Keith L Keene, Brett M Kissela, Dawn O Kleindorfer, Simon Koblar, Daniel Labovitz, Lenore J Launer, Cathy C Laurie, Cecelia A Laurie, Cue Hyunkyu Lee, Jin-Moo Lee, Manuel Lehm, Robin Lemmens, Christopher Levi, Didier Leys, Arne Lindgren, W T Longstreth, Jane Maguire, Ani Manichaikul, Hugh S Markus, Leslie A McClure, Caitrin W McDonough, Christa Meisinger, Olle Melander, James F Meschia, Marina Mola-Caminal, Joan Montaner, Thomas H Mosley, Martina Müller-Nurasyid, Mike A Nalls, Jeffrey R O'Connell, Martin O'Donnell, ángel Ois, George J Papanicolaou, Guillaume Paré, Leema Reddy Peddareddygari, Annie Pedersén, Joanna Pera, Annette Peters, Deborah Poole, Bruce M Psaty, Raquel Rabionet, Miriam R Raffeld, Kristiina Rannikmäe, Asif Rasheed, Petra Redfors, Alex P Reiner, Kathryn Rexrode, Marta Ribasés, Stephen S Rich, Wim Robberecht, Ana Rodriguez-Campello, Arndt Rolfs, Jaume Roquer, Lynda M Rose, Daniel Rosenbaum, Natalia S Rost, Peter M Rothwell, Tatjana Rundek, Kathleen A Ryan, Ralph L Sacco, Michèle M Sale, Danish Saleheen, Veikko Salomaa, Cristina Sánchez-Mora, Carsten Oliver Schmidt, Helena Schmidt, Reinhold Schmidt, Markus Schürks, Rodney Scott, Helen C Segal, Stephan Seiler, Sudha Seshadri, Pankaj Sharma, Alan R Shuldiner, Brian Silver, Agnieszka Slowik, Jennifer A Smith, Martin Söderholm, Carolina Soriano, Mary J Sparks, Tara Stanne, Kari Stefansson, O Colin Stine, Konstantin Strauch, Jonathan Sturm, Cathie LM Sudlow, Salman M Tajuddin, Robert L Talbert, Turgut Tatlisumak, Vincent Thijs, Gudmar Thorleifsson, Unnur Thorsteindottir, Steffen Tiedt, Matthew Traylor, Stella Trompet, Valerie Valant, Melanie Waldenberger, Matthew Walters, Liyong Wang, Sylvia Wassertheil-Smoller, David R Weir, Kerri L Wiggins, Stephen R Williams, Dorota Wloch-Kopec, Daniel Woo, Rebecca Woodfield, Ona Wu, Huichun Xu, Alan B Zonderman, Bradford B Worrall, Paul IW de Bakker, Steven J Kittner, Braxton D Mitchell, Jonathan Rosand, Cathie L M Sudlow, Bradford B Worrall Worrall, Donna K Arnett Arnett, Oscar Benavente, Sylvia Wasssertheil-Smoller

Publikováno v: Lancet Neurology, 15(2), 174. Lancet Publishing Group

Summary Background The discovery of disease-associated loci through genome-wide association studies (GWAS) is the leading genetic approach to the identification of novel biological pathways underlying diseases in humans. Until recently, GWAS in ischa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c29eee423fd89a047d0ae6bc637d79a
https://hdl.handle.net/1874/342770

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Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease

Autor: Thomas J, Kunicki, Shirley A, Williams, Diane J, Nugent, Paul, Harrison, Helen C, Segal, Anila, Syed, Peter M, Rothwell

Publikováno v: Thrombosis and haemostasis. 101(1)

We studied the effect of prophylactic aspirin (ASA) ingestion on platelet function in 463 patients with stroke, transient ischemic attack (TIA) or acute coronary disease (ACD), using the Platelet Function Analyzer-100 (PFA-100). We correlated ASA res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55e3fbe7cfe07196677f1f883b6041b3
https://pubmed.ncbi.nlm.nih.gov/19132198

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Methods for counting platelets in severe thrombocytopenia

Autor: Helen C, Segal, Paul, Harrison

Publikováno v: Current hematology reports. 5(1)

Accurate platelet counts in severe thrombocytopenia are critical in clinical practice to facilitate decisions at prophylactic platelet-transfusion thresholds. Until recent years, the accuracy of platelet counts has been limited by the reliance of hem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::77a2cf6dcbd3d7f84ef7afb16558db56
https://pubmed.ncbi.nlm.nih.gov/16537049

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Activation of coagulation and fibrinolysis during cardiothoracic operations

Autor: Beverley J Hunt, Sajila Sheikh, Rachel Parratt, Magdi H. Yacoub, Panny Kallis, Helen C Segal

Publikováno v: The Annals of thoracic surgery. 65(3)

Background . During open cardiac operations using cardiopulmonary bypass, there is activation of coagulation and fibrinolysis. We assessed the separate contributions of the surgical procedure itself and cardiopulmonary bypass to this, by studying seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687ba6fd7bbb26d00aa5acfe8a6b9fb1
https://pubmed.ncbi.nlm.nih.gov/9527200

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The effects of alginate and non-alginate wound dressings on blood coagulation and platelet activation

Autor: Helen C. Segal, K. Gilding, Beverley J. Hunt

Publikováno v: Journal of biomaterials applications. 12(3)

Alginates are used as haemostats in wound dressings. They act as calcium ion (Ca) donors as they contain mannuronic (M) or guluronic (G) groups with a high Ca content. This study compared the effects of calcium and zinc containing alginates and non-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bea031b057285005f041cbbcdae18c2
https://pubmed.ncbi.nlm.nih.gov/9493071

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Coagulation and fibrinolysis in primary biliary cirrhosis compared with other liver disease and during orthotopic liver transplantation

Autor: Helen C. Segal, Simon Cottam, Beverley J. Hunt, Dennis Potter

Publikováno v: Hepatology (Baltimore, Md.). 25(3)

Cirrhosis is associated with compromised hemostasis and coagulopathy during orthotopic liver transplantation (OLT). It has been suggested that hemostasis is better preserved during OLT in primary biliary cirrhosis (PBC) than other cirrhotic states. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1811c8977a7ad821553f8fc0071808bb
https://pubmed.ncbi.nlm.nih.gov/9049219

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Endothelial Cell Hemostatic Function after Heart Transplantation

Autor: Beverley J. Hunt, Magdi H. Yacoub, Helen C. Segal

Publikováno v: Vascular Endothelium ISBN: 9781461366638

We hypothesize that derangement of endothelial cell hemostatic function may be involved in the development of accelerated atherosclerosis (AA), (which is the major cause of mortality in heart transplant recipients (HTR) after their first year). Endot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a7c293698c4f2ff0a39949de3dbb161
https://doi.org/10.1007/978-1-4615-3736-6_37

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