Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Helen C. Jackson"'
Autor:
Helen C. Jackson
This chapter documents the experiences in the journey of an African American female physicist. They correspond to those in documented studies of other African Americans and females in both the specific field of physics as well as the broader area of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e771e5667e6a4a86a433997ba81cdb
https://doi.org/10.4018/978-1-5225-8870-2.ch004
https://doi.org/10.4018/978-1-5225-8870-2.ch004
Autor:
Malcolm J. Sheardown, K. Eskesen, Peter D. Suzdak, Palle Jacobsen, Helen C. Jackson, Christian Thomsen, Henrik Klitgaard, Svend Treppendahl
Publikováno v:
Journal of Neurochemistry. 62:2492-2495
The in vivo anticonvulsant effects and in vitro metabotropic glutamate receptor selectivity of (S)-4-carboxy-3-hydroxy-phenylglycine [(S)-4C3HPG] were examined. Intracerebroventricular injection of (S)-4C3HPG dose-dependently antagonized audiogenic-i
Current regulatory hurdles, the withdrawal of several drugs due to safety concerns, modest weight-loss efficacy using existing drugs and the lack of reimbursement in the US has resulted in limited investment in research and development of anti-obesit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4fa260a1d7d215c3345cc9c7650b542
https://doi.org/10.1039/9781782622390-00090
https://doi.org/10.1039/9781782622390-00090
Publikováno v:
Journal of Neuroscience Methods. 147:48-54
Antisense oligonucleotides have been used to target a range of different gene products in the CNS including neurotransmitter receptors. Previous studies using antisense oligonucleotides to target the rat α 2A/D -adrenoceptor revealed changes in rece
Publikováno v:
Journal of Antimicrobial Chemotherapy. 51:977-990
A mathematical model of influenza transmission dynamics is used to simulate the impact of neuraminidase inhibitor therapy on infection rates and transmission of drug-resistant viral strains. The model incorporates population age structure, seasonal t
Publikováno v:
Clinical Drug Investigation. 20:447-454
In most years epidemics of influenza cause a significant increase in morbidity and mortality worldwide. With the availability of a new class of antivirals targeting the viral protein neuraminidase, there are new options for the control of influenza.
Publikováno v:
British Journal of Pharmacology. 130:153-159
1 The aim of this study was to investigate the behavioural and physiological eAects of an i.c.v. infusion of antisense oligonucleotide to the a2D-adrenoceptor subtype. Behavioural and physiological parameters were monitored for 2 days before the infu
Publikováno v:
British Journal of Pharmacology. 128:515-522
The aims of this study were, firstly to use receptor autoradiography to investigate the effect of antisense oligonucleotides to the α2D-adrenoceptor on receptor binding and, secondly to measure behavioural and physiological parameters to determine w
Autor:
Andrew M. Needham, Sarah E. Mazurkiewicz, Helen C. Jackson, M. Clair Bearham, David J. Heal, Lisa J. Hutchins
Publikováno v:
British Journal of Pharmacology. 121:1613-1618
1Sibutramine is a novel 5-hydroxytryptamine (5-HT) and noradrenaline reuptake inhibitor (serotonin- noradrenaline reuptake inhibitor, SNRI) which is currently being developed as a treatment for obesity. Sibutramine has been shown to decrease food int
Publikováno v:
British Journal of Pharmacology. 121:1758-1762
1. The effects of the potent 5-hydroxytryptamine (5-HT) and noradrenaline reuptake inhibitor (serotonin-noradrenaline reuptake inhibitor, SNRI), sibutramine, on the cumulative food intake of freely-feeding male Sprague-Dawley rats during an 8 h dark