Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Helen C O'Neill"'
Autor:
Helen C O'Neill, Hong K Lim, Pravin Periasamy, Lavanya Kumarappan, Jonathan K H Tan, Terence J O'Neill
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223416 (2019)
Spleen stromal lines which support in vitro hematopoiesis are investigated for their lineage origin and hematopoietic support function in vivo. Marker expression and gene profiling identify a lineage relationship with mesenchymal stem cells and periv
Externí odkaz:
https://doaj.org/article/d162046c4b0944c79fca7dfde01cda89
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205583 (2018)
Cultured splenic stroma has been shown to support in vitro hematopoiesis in overlaid bone marrow and spleen progenitors. These co-cultures support longterm production of a novel dendritic-like cell type along with transient production of myeloid cell
Externí odkaz:
https://doaj.org/article/c54f32e90adc4247b45f73a6f6b45d51
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006584 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.1006520.].
Externí odkaz:
https://doaj.org/article/9c040fca61a94a8bb793005e73fcaf5a
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006520 (2017)
During mouse sex determination, transient expression of the Y-linked gene Sry up-regulates its direct target gene Sox9, via a 3.2 kb testis specific enhancer of Sox9 (TES), which includes a core 1.4 kb element, TESCO. SOX9 activity leads to different
Externí odkaz:
https://doaj.org/article/cc440842b5db4a9eb84a74836d354bcf
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176345 (2017)
Booreana mice carrying the c-Myb308G point mutation were analyzed to determine changes in early hematopoiesis in the bone marrow and among mature cells in the periphery. This point mutation led to increased numbers of early hematopoietic stem and pro
Externí odkaz:
https://doaj.org/article/69cc6d1d85bb403cb6f753a9ae5628e0
Autor:
Ying-Ying Hey, Helen C O'Neill
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162358 (2016)
This paper distinguishes a rare subset of myeloid dendritic-like cells found in mouse spleen from conventional (c) dendritic cells (DC) in terms of phenotype, function and gene expression. These cells are tentatively named "L-DC" since they resemble
Externí odkaz:
https://doaj.org/article/ce0550c8b52542c39633eea4e7e30f8b
Autor:
Sawang Petvises, Helen C O'Neill
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88311 (2014)
Heterogeneity amongst dendritic cell (DC) subsets leads to a spectrum of immune response capacity against pathogens. Several DC subsets in spleen have been described which differ in terms of phenotype and function. We have previously reported a disti
Externí odkaz:
https://doaj.org/article/5ae2f553f1514bee8efc4434309f741d
Publikováno v:
F&S Science. 4:17-26
Publikováno v:
Fertility and Sterility. 119:562-569
Autor:
Hong Kiat Lim, Helen C. O’Neill
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Stromal cells in spleen organize tissue into red pulp, white pulp and marginal zone, and also interact with hematopoietic cells to regulate immune responses. This study has used phenotypic information of a previously described spleen stromal cell lin
Externí odkaz:
https://doaj.org/article/747b852bee43458cafb0989a2d2a9773