Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Helen Brosi"'
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71746 (2013)
Coinhibitory PD-1/PD-L1 (B7-H1) interactions provide critical signals for the regulation of autoreactive T-cell responses. We established mouse models, expressing the costimulator molecule B7.1 (CD80) on pancreatic beta cells (RIP-B7.1 tg mice) or ar
Externí odkaz:
https://doaj.org/article/a700c52b344440fb9c263801b4a1d348
Autor:
Bernhard O. Boehm, Andreas Spyrantis, Reinhold Schirmbeck, Cornelia Schuster, Jörg Reimann, Helen Brosi, Lieping Chen, Tarvo Rajasalu
Publikováno v:
Diabetes
OBJECTIVE RIP-B7.1 mice expressing the costimulator molecule B7.1 (CD80) on pancreatic β-cells are a well established model to characterize preproinsulin-specific CD8 T-cell responses and experimental autoimmune diabetes (EAD). Different immunizatio
Autor:
Ilona Frindi-Wosch, Michael Müller, Thorsten Gräf, Lydia Walter, Dörte Gocke, Martina Pohl, Helen Brosi
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 61:30-35
Several 2-keto acid decarboxylases catalyse an acyloin condensation-like carboligase reaction beside their physiological decarboxylase activity. Although many data concerning stability and catalytic potential of these enzymes are available, a standar
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71746 (2013)
PLoS ONE
PLoS ONE
Coinhibitory PD-1/PD-L1 (B7-H1) interactions provide critical signals for the regulation of autoreactive T-cell responses. We established mouse models, expressing the costimulator molecule B7.1 (CD80) on pancreatic beta cells (RIP-B7.1 tg mice) or ar
Autor:
Bernhard O. Boehm, Tarvo Rajasalu, Reinhold Schirmbeck, Franz Oswald, Andreas Spyrantis, Helen Brosi, Michael L. Reiser
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 183(11)
RIP-B7.1 mice express the costimulator molecule B7.1 (CD80) on pancreatic β cells and are a well-established model for studying de novo induction of diabetogenic CD8 T cells. Immunization of RIP-B7.1 mice with preproinsulin (ppins)-encoding plasmid