Zobrazeno 1 - 10
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pro vyhledávání: '"Helen B Fleisig"'
Telomerase is the ribonucleoprotein reverse transcriptase that catalyzes the synthesis of telomeres at the ends of linear chromosomes and contributes to proper telomere-loop (T-loop) formation. Formation of the T-loop, an obligate step before cell di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21c73c7bb6475ea62a23b4e1f8ae9016
https://doi.org/10.1158/1541-7786.c.6541254
https://doi.org/10.1158/1541-7786.c.6541254
Supplementary Figure 1. Imetelstat reduces cell number in telomerase positive cell lines in a dose-dependent manner following 7-day incubation. Supplementary Figure 2. Imetelstat inhibits telomerase activity in a dose dependent manner. Supplementary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e2ffe3bcad96c11fa8f557d6146c62
https://doi.org/10.1158/1541-7786.22516014
https://doi.org/10.1158/1541-7786.22516014
Supplementary Methods, Figure Legends 1-3 from Telomerase Inhibition Potentiates the Effects of Genotoxic Agents in Breast and Colorectal Cancer Cells in a Cell Cycle–Specific Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f72f9bc9daff54bdffec0e238da3c0b
https://doi.org/10.1158/0008-5472.22388099
https://doi.org/10.1158/0008-5472.22388099
Supplementary Figure 2A from Telomerase Inhibition Potentiates the Effects of Genotoxic Agents in Breast and Colorectal Cancer Cells in a Cell Cycle–Specific Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac365e0a282800f4fdc9160dbeee738
https://doi.org/10.1158/0008-5472.22388105
https://doi.org/10.1158/0008-5472.22388105
Supplementary Figure 3 from Telomerase Inhibition Potentiates the Effects of Genotoxic Agents in Breast and Colorectal Cancer Cells in a Cell Cycle–Specific Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61be156f5db29a9086072e7d86a14704
https://doi.org/10.1158/0008-5472.22388102
https://doi.org/10.1158/0008-5472.22388102
Supplementary Figure 1 from Telomerase Inhibition Potentiates the Effects of Genotoxic Agents in Breast and Colorectal Cancer Cells in a Cell Cycle–Specific Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a971f2de4118f75617784ed243cd5e
https://doi.org/10.1158/0008-5472.22388111.v1
https://doi.org/10.1158/0008-5472.22388111.v1
Autor:
C R Zhao, Kyle R. Hukezalie, T T T Au-Yeung, Helen B. Fleisig, Andrew T. Ludlow, Connor A. H. Thompson, Judy M. Y. Wong
Publikováno v:
Oncogene. 35:218-227
Reactivation of telomerase reverse transcriptase (TERT) expression is found in more than 85% of human cancers. The remaining cancers rely on the alternative lengthening of telomeres (ALT), a recombination-based mechanism for telomere-length maintenan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce175b60c4fc15d49c351a4ad9e4d457
https://doi.org/10.1038/onc.2015.75
https://doi.org/10.1038/onc.2015.75
Autor:
Sunny Y. Yang, Connor A. H. Thompson, Veena Mathew, Helen B. Fleisig, Alice Y. M. Gu, Judy M. Y. Wong
Publikováno v:
Molecular cancer research : MCR. 16(8)
Telomerase is the ribonucleoprotein reverse transcriptase that catalyzes the synthesis of telomeres at the ends of linear chromosomes and contributes to proper telomere-loop (T-loop) formation. Formation of the T-loop, an obligate step before cell di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d0979643f25a1bde8c5436b52ecbc7
https://pubmed.ncbi.nlm.nih.gov/29759988
https://pubmed.ncbi.nlm.nih.gov/29759988
Autor:
Judy M. Y. Wong, Veena Mathew, Sunny Y. Yang, Connor A. H. Thompson, Helen B. Fleisig, Alice Y. M. Gu
Telomerase is the ribonucleoprotein reverse transcriptase that catalyzes the synthesis of telomeres at the ends of linear human chromosomes and contributes to proper telomere-loop (T-loop) formation. Formation of the T-loop, an obligate step before c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c93e0625909d76487b4d1a7b003551
https://doi.org/10.1101/158287
https://doi.org/10.1101/158287
Autor:
Xi Lei Zeng, Helen B. Fleisig, Kyle R. Hukezalie, Blanche P. Alter, Sharon A. Savage, Judy M. Y. Wong, Neelam Giri, Naresh R. Thumati
Publikováno v:
Human Molecular Genetics. 21:721-729
X-linked dyskeratosis congenita (X-DC) is caused by mutations in the housekeeping nucleolar protein dyskerin. Amino acid changes associated with X-DC are remarkably heterogeneous. Peripheral mononuclear blood cells and fibroblasts isolated from X-DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2390ba15a02585f9a0a7780a5c273011
https://doi.org/10.1093/hmg/ddr504
https://doi.org/10.1093/hmg/ddr504