Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Helen Zhu"'
Autor:
Michelle M. Kameda-Smith, Helen Zhu, En-Ching Luo, Yujin Suk, Agata Xella, Brian Yee, Chirayu Chokshi, Sansi Xing, Frederick Tan, Raymond G. Fox, Ashley A. Adile, David Bakhshinyan, Kevin Brown, William D. Gwynne, Minomi Subapanditha, Petar Miletic, Daniel Picard, Ian Burns, Jason Moffat, Kamil Paruch, Adam Fleming, Kristin Hope, John P. Provias, Marc Remke, Yu Lu, Tannishtha Reya, Chitra Venugopal, Jüri Reimand, Robert J. Wechsler-Reya, Gene W. Yeo, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
MYC amplification is an independent prognostic factor for the most aggressive subgroup (Group 3) of pediatric medulloblastoma (G3 MB). Here, the authors highlight the role of the RNA-binding protein, Musashi-1 (MSI1) in G3 MB and identify MSI1-bound
Externí odkaz:
https://doaj.org/article/3eace71e4f774decb598d79c690ed3aa
Autor:
Patryk Skowron, Hamza Farooq, Florence M. G. Cavalli, A. Sorana Morrissy, Michelle Ly, Liam D. Hendrikse, Evan Y. Wang, Haig Djambazian, Helen Zhu, Karen L. Mungall, Quang M. Trinh, Tina Zheng, Shizhong Dai, Ana S. Guerreiro Stucklin, Maria C. Vladoiu, Vernon Fong, Borja L. Holgado, Carolina Nor, Xiaochong Wu, Diala Abd-Rabbo, Pierre Bérubé, Yu Chang Wang, Betty Luu, Raul A. Suarez, Avesta Rastan, Aaron H. Gillmor, John J. Y. Lee, Xiao Yun Zhang, Craig Daniels, Peter Dirks, David Malkin, Eric Bouffet, Uri Tabori, James Loukides, François P. Doz, Franck Bourdeaut, Olivier O. Delattre, Julien Masliah-Planchon, Olivier Ayrault, Seung-Ki Kim, David Meyronet, Wieslawa A. Grajkowska, Carlos G. Carlotti, Carmen de Torres, Jaume Mora, Charles G. Eberhart, Erwin G. Van Meir, Toshihiro Kumabe, Pim J. French, Johan M. Kros, Nada Jabado, Boleslaw Lach, Ian F. Pollack, Ronald L. Hamilton, Amulya A. Nageswara Rao, Caterina Giannini, James M. Olson, László Bognár, Almos Klekner, Karel Zitterbart, Joanna J. Phillips, Reid C. Thompson, Michael K. Cooper, Joshua B. Rubin, Linda M. Liau, Miklós Garami, Peter Hauser, Kay Ka Wai Li, Ho-Keung Ng, Wai Sang Poon, G. Yancey Gillespie, Jennifer A. Chan, Shin Jung, Roger E. McLendon, Eric M. Thompson, David Zagzag, Rajeev Vibhakar, Young Shin Ra, Maria Luisa Garre, Ulrich Schüller, Tomoko Shofuda, Claudia C. Faria, Enrique López-Aguilar, Gelareh Zadeh, Chi-Chung Hui, Vijay Ramaswamy, Swneke D. Bailey, Steven J. Jones, Andrew J. Mungall, Richard A. Moore, John A. Calarco, Lincoln D. Stein, Gary D. Bader, Jüri Reimand, Jiannis Ragoussis, William A. Weiss, Marco A. Marra, Hiromichi Suzuki, Michael D. Taylor
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Sonic Hedgehog medulloblastoma (Shh-MB) comprises four subtypes each with distinct clinical traits. Here the authors characterize the genome, transcriptome, and methylome of Shh-MB subtypes, revealing a complex fusion landscape and the molecular conv
Externí odkaz:
https://doaj.org/article/091429a4162845e7a18371f487596c6f
Autor:
Marta Paczkowska, Jonathan Barenboim, Nardnisa Sintupisut, Natalie S. Fox, Helen Zhu, Diala Abd-Rabbo, Miles W. Mee, Paul C. Boutros, PCAWG Drivers and Functional Interpretation Working Group, Jüri Reimand, PCAWG Consortium
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Multi-omics datasets pose major challenges to data interpretation and hypothesis generation owing to their high-dimensional molecular profiles. Here, the authors develop ActivePathways method, which uses data fusion techniques for integrative pathway
Externí odkaz:
https://doaj.org/article/0e1be01e74114d78838f12db1d7166ab
Autor:
Michelle M. Kameda-Smith, Helen Zhu, En-Ching Luo, Yujin Suk, Agata Xella, Brian Yee, Chirayu Chokshi, Sansi Xing, Frederick Tan, Raymond G. Fox, Ashley A. Adile, David Bakhshinyan, Kevin Brown, William D. Gwynne, Minomi Subapanditha, Petar Miletic, Daniel Picard, Ian Burns, Jason Moffat, Kamil Paruch, Adam Fleming, Kristin Hope, John P. Provias, Marc Remke, Yu Lu, Tannishtha Reya, Chitra Venugopal, Jüri Reimand, Robert J. Wechsler-Reya, Gene W. Yeo, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a3f8e3d5b4894e4aa4350454d71f0f4e
Autor:
Marta Paczkowska, Jonathan Barenboim, Nardnisa Sintupisut, Natalie S. Fox, Helen Zhu, Diala Abd-Rabbo, Miles W. Mee, Paul C. Boutros, PCAWG Drivers and Functional Interpretation Working Group, Jüri Reimand, PCAWG Consortium
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/61749623601a4b968c0a7a886d45a2e8
Autor:
Kathleen E Houlahan, Julie Livingstone, Natalie S Fox, Natalie Kurganovs, Helen Zhu, Jocelyn Sietsma Penington, Chol-Hee Jung, Takafumi N Yamaguchi, Lawrence E Heisler, Richard Jovelin, Anthony J Costello, Bernard J Pope, Amar U Kishan, Niall M Corcoran, Robert G Bristow, Sebastian M Waszak, Joachim Weischenfeldt, Housheng H He, Rayjean J Hung, Christopher M Hovens, Paul C Boutros
Publikováno v:
JNCI: Journal of the National Cancer Institute. 115:468-472
Prostate cancer is one of the most heritable cancers. Hundreds of germline polymorphisms have been linked to prostate cancer diagnosis and prognosis. Polygenic risk scores can predict genetic risk of a prostate cancer diagnosis. Although these scores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e3648371275d70d4c6367fe6c12732
https://doi.org/10.1093/jnci/djad001
https://doi.org/10.1093/jnci/djad001
Autor:
Glenn Fernandes, Helen Zhu, Mahdi Pedram, Jacob Schauer, Soroush Shahi, Christopher Romano, Darren Gergle, Nabil Alshurafa
Publikováno v:
Extended Abstracts of the 2023 CHI Conference on Human Factors in Computing Systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a63d27edc2960632fbe1c64b84f0efea
https://doi.org/10.1145/3544549.3585812
https://doi.org/10.1145/3544549.3585812
Autor:
Trevor J. Pugh, Mathieu Lupien, Susan J. Done, Dave W. Cescon, Jüri Reimand, Paul Guilhamon, S.Y. Cindy Yang, Leslie E. Oldfield, Jeff P. Bruce, Helen Zhu, Iulia Cirlan, Youstina Hanna, Parisa Mazrooei, James Hawley, Rene Quevedo, Samah El Ghamrasni
Whole-genome sequencing of primary breast tumors enabled the identification of cancer driver genes and noncoding cancer driver plexuses from somatic mutations. However, differentiating driver from passenger events among noncoding genetic variants rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a976ceefb6fe1848c7e09f0e6661a1a
https://doi.org/10.1158/1541-7786.c.6545226.v1
https://doi.org/10.1158/1541-7786.c.6545226.v1
Autor:
Trevor J. Pugh, Mathieu Lupien, Susan J. Done, Dave W. Cescon, Jüri Reimand, Paul Guilhamon, S.Y. Cindy Yang, Leslie E. Oldfield, Jeff P. Bruce, Helen Zhu, Iulia Cirlan, Youstina Hanna, Parisa Mazrooei, James Hawley, Rene Quevedo, Samah El Ghamrasni
Supplementary Figure from Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002d1a40bf6c1777c932897b393e09e5
https://doi.org/10.1158/1541-7786.22526841.v1
https://doi.org/10.1158/1541-7786.22526841.v1
Autor:
Trevor J. Pugh, Mathieu Lupien, Susan J. Done, Dave W. Cescon, Jüri Reimand, Paul Guilhamon, S.Y. Cindy Yang, Leslie E. Oldfield, Jeff P. Bruce, Helen Zhu, Iulia Cirlan, Youstina Hanna, Parisa Mazrooei, James Hawley, Rene Quevedo, Samah El Ghamrasni
Supplementary Table from Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129f0224300ad2d003e63521ab862238
https://doi.org/10.1158/1541-7786.22526838
https://doi.org/10.1158/1541-7786.22526838