Zobrazeno 1 - 10
of 462
pro vyhledávání: '"Helen Leonard"'
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Introduction Rett syndrome (RTT) is a rare neurodevelopmental disorder with developmental impairments, comorbidities, and abnormal behaviours such as hand stereotypies and emotional features. The Rett Syndrome Behaviour Questionnaire (RSBQ)
Externí odkaz:
https://doaj.org/article/484f4ac2ffa14d4e84c4bb4aa09aa397
Autor:
Walter E. Kaufmann, Alan K. Percy, Jeffrey L. Neul, Jenny Downs, Helen Leonard, Paige Nues, Girish D. Sharma, Theresa E. Bartolotta, Gillian S. Townend, Leopold M. G. Curfs, Orietta Mariotti, Claude Buda, Heather M. O’Leary, Lindsay M. Oberman, Vanessa Vogel-Farley, Katherine V. Barnes, Christopher U. Missling
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Rett syndrome (RTT) is a severe X-linked neurodevelopmental disorder associated with multiple neurologic impairments. Previous studies have shown challenges to the quality of life of individuals with RTT and their caregivers. Howe
Externí odkaz:
https://doaj.org/article/9f2f215cd3a24fd58dac55f46755ce60
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionEstimates of the prevalence of intellectual disability or autism spectrum disorder (ASD) may vary depending on the methodology, geographical location, and sources of ascertainment. The National Disability Insurance Scheme (NDIS) in Austra
Externí odkaz:
https://doaj.org/article/ed6e9a2931fe4667a6971d566d9bbea2
Autor:
Dheeraj Rai, Doug Webb, Amanda Lewis, Leonora Cotton, Jade Eloise Norris, Regi Alexander, David S. Baldwin, Traolach Brugha, Madeleine Cochrane, Maria Chiara Del Piccolo, Emma J. Glasson, Katherine K. Hatch, David Kessler, Peter E. Langdon, Helen Leonard, Stephanie J. MacNeill, Nicola Mills, Maximiliano Vazquez Morales, Zoe Morgan, Raja Mukherjee, Alba X. Realpe, Ailsa Russell, Sergio Starkstein, Jodi Taylor, Nicholas Turner, Joanna Thorn, Jack Welch, on behalf of the STRATA autistic advisory group, Nicola Wiles
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-20 (2024)
Abstract Background Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed to manage anxiety in adults with an autism diagnosis. However, their effectiveness and adverse effect profile in the autistic population are not well known. T
Externí odkaz:
https://doaj.org/article/dcf5728c9f524919a95e54ac2b254489
Autor:
Tamara Ondruskova, Rachel Royston, Michael Absoud, Gareth Ambler, Chen Qu, Jacqueline Barnes, Rachael Hunter, Monica Panca, Marinos Kyriakopoulos, Kate Oulton, Eleni Paliokosta, Aditya Narain Sharma, Vicky Slonims, Una Summerson, Alastair Sutcliffe, Megan Thomas, Brindha Dhandapani, Helen Leonard, Angela Hassiotis
Publikováno v:
Health Technology Assessment, Vol 28, Iss 06 (2024)
Background Stepping Stones Triple P is an adapted intervention for parents of young children with developmental disabilities who display behaviours that challenge, aiming at teaching positive parenting techniques and promoting a positive parent–chi
Externí odkaz:
https://doaj.org/article/0815ca67fb5c41a9928fe9410c3956a0
Autor:
Emine Bircan, Maria D. Politis, Yevgeniya Gokun, Chunqiao Luo, Helen Leonard, Jenny Bourke, Carol Bower, Wendy N. Nembhard
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Children with congenital heart defects (CHDs) are at higher risk of developing an intellectual disability. However, severity of intellectual disabilities among this group of children are largely unknown. Our objective was to deter
Externí odkaz:
https://doaj.org/article/280a61e01dbc4cf1b24fffcf356e20df
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-15 (2022)
Abstract Rett syndrome is associated with severe functional impairments and many comorbidities, each in urgent need of treatments. Mutations in the MECP2 gene were identified as causing Rett syndrome in 1999. Over the past 20 years there has been an
Externí odkaz:
https://doaj.org/article/76fbfe254a3e47fd8cf4a21344d457f4
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-21 (2022)
Abstract MECP2 duplication syndrome (MDS) is a rare, X-linked, neurodevelopmental disorder caused by a duplication of the methyl-CpG-binding protein 2 (MECP2) gene—a gene in which loss-of-function mutations lead to Rett syndrome (RTT). MDS has an e
Externí odkaz:
https://doaj.org/article/e0a0939a855b49fa884e99849975f4ba
Autor:
Helen Leonard, Alicia Montgomery, Brittany Wolff, Elissa Strumpher, Anne Masi, Susan Woolfenden, Katrina Williams, Valsamma Eapen, Amy Finlay-Jones, Andrew Whitehouse, Martyn Symons, Melissa Licari, Kandice Varcin, Gail Alvares, Kiah Evans, Jenny Downs, Emma Glasson
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
AimThis systematic review aimed to identify the most important social, environmental, biological, and/or genetic risk factors for intellectual disability (ID).MethodsEligible were published prospective or retrospective comparative studies investigati
Externí odkaz:
https://doaj.org/article/29b4681597804196bf5155d3e67d082f
Autor:
Alison Gibberd, Sandra Eades, Nicoletta Psilos, Jenny Bourke, Helen Leonard, Emma Carlin, Anne Kavanagh, Roz Walker, Melissa O'Donnell, Rebecca Colbung, Lesley Nelson
Publikováno v:
International Journal of Population Data Science, Vol 7, Iss 3 (2022)
Background While Aboriginal Australians are known to be disproportionately affected by intellectual disabilities (ID) and/or autism spectrum disorders (developmental disabilities), true prevalences among Aboriginal children are unclear, with evidence
Externí odkaz:
https://doaj.org/article/1541421a96f4496ba856b00b54190c6f