Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Helen Irving"'
Autor:
Leon M J Mugenzi, Theofelix A Tekoh, Stevia T Ntadoun, Achille D Chi, Mahamat Gadji, Benjamin D Menze, Magellan Tchouakui, Helen Irving, Murielle J Wondji, Gareth D Weedall, Jack Hearn, Charles S Wondji
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011344 (2024)
Deciphering the evolutionary forces controlling insecticide resistance in malaria vectors remains a prerequisite to designing molecular tools to detect and assess resistance impact on control tools. Here, we demonstrate that a 4.3kb transposon-contai
Externí odkaz:
https://doaj.org/article/61b38649e8a4405aa938056bbaf281fd
Autor:
Ilona Turek, Aloysius Wong, Guido Domingo, Candida Vannini, Marcella Bracale, Helen Irving, Chris Gehring
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9535 (2024)
Increasing numbers of reports have revealed novel catalytically active cryptic guanylate cyclases (GCs) and adenylate cyclases (ACs) operating within complex proteins in prokaryotes and eukaryotes. Here we review the structural and functional aspects
Externí odkaz:
https://doaj.org/article/1f8f9f38961647d0934a2230e5381e4c
Autor:
Amen N. Fadel, Sulaiman S. Ibrahim, Maurice M. Sandeu, Claudine Grâce Maffo Tatsinkou, Benjamin D. Menze, Helen Irving, Jack Hearn, Sanjay C. Nagi, Gareth D. Weedall, Ebai Terence, Williams Tchapga, Samuel Wanji, Charles S. Wondji
Publikováno v:
Evolutionary Applications, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract Molecular mechanisms driving the escalation of pyrethroid resistance in the major malaria mosquitoes of Central Africa remain largely uncharacterized, hindering effective management strategies. Here, resistance intensity and the molecular me
Externí odkaz:
https://doaj.org/article/579590c7f9364bfaa87f102af9bfae16
Autor:
Sulaiman S. Ibrahim, Mersimine F. M. Kouamo, Abdullahi Muhammad, Helen Irving, Jacob M. Riveron, Magellan Tchouakui, Charles S. Wondji
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8092 (2024)
The versatility of cytochrome P450 reductase (CPR) in transferring electrons to P450s from other closely related species has been extensively exploited, e.g., by using An. gambiae CPR (AgCPR), as a homologous surrogate, to validate the role of An. fu
Externí odkaz:
https://doaj.org/article/c9cc0199444d4a5b8cf776305608f961
Autor:
Sulaiman S. Ibrahim, Abdullahi Muhammad, Jack Hearn, Gareth D. Weedall, Sanjay C. Nagi, Muhammad M. Mukhtar, Amen N. Fadel, Leon J. Mugenzi, Edward I. Patterson, Helen Irving, Charles S. Wondji
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background Information on common markers of metabolic resistance in malaria vectors from countries sharing similar eco-climatic characteristics can facilitate coordination of malaria control. Here, we characterized populations of the major m
Externí odkaz:
https://doaj.org/article/6239ec4a6e0a4d75bc5c9e5d02cc6d77
Autor:
Ilona Turek, Lubna Freihat, Jignesh Vyas, Janet Wheeler, Victor Muleya, David T. Manallack, Chris Gehring, Helen Irving
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5523-5529 (2023)
Recent discoveries have established functional guanylate cyclase (GC) catalytic centers with low activity within kinase domains in plants. These crypto GCs generate guanosine 3’,5’-cyclic monophosphate (cGMP) essential for both intramolecular and
Externí odkaz:
https://doaj.org/article/384e8655648d4d2eaf0f31081b09ee20
Autor:
Leon M J Mugenzi, Theofelix A Tekoh, Sulaiman S Ibrahim, Abdullahi Muhammad, Mersimine Kouamo, Murielle J Wondji, Helen Irving, Jack Hearn, Charles S Wondji
Publikováno v:
PLoS Genetics, Vol 19, Iss 3, p e1010678 (2023)
Cross-resistance to insecticides in multiple resistant malaria vectors is hampering resistance management. Understanding its underlying molecular basis is critical to implementation of suitable insecticide-based interventions. Here, we established th
Externí odkaz:
https://doaj.org/article/292649815bda4bfa9c46f5e02bda0045
Autor:
Helen Irving
To have a nationality is a human right. But between the nineteenth and mid-twentieth centuries, virtually every country in the world adopted laws that stripped citizenship from women who married foreign men. Despite the resulting hardships and even s
Autor:
Siti Saleha Binte Mohamed Yakob Adil, Mwila Kabwe, Cassandra Cianciarulo, Trang Hong Nguyen, Helen Irving, Joseph Tucci
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15108 (2023)
Microbial resistance to antibiotics poses a tremendous challenge. Bacteriophages may provide a useful alternative or adjunct to traditional antibiotics. To be used in therapy, bacteriophages need to be purified from endotoxins and tested for their ef
Externí odkaz:
https://doaj.org/article/25e497dab4174cb18510b5abf0f0c08a
Autor:
Ilona Turek, Trang H. Nguyen, Charles Galea, Isaiah Abad, Lubna Freihat, David T. Manallack, Tony Velkov, Helen Irving
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8572 (2023)
Interleukin-1 receptor-associated kinase 3 (IRAK3) modulates the magnitude of cellular responses to ligands perceived by interleukin-1 receptors (IL-1Rs) and Toll-like receptors (TLRs), leading to decreases in pro-inflammatory cytokines and suppresse
Externí odkaz:
https://doaj.org/article/9f6ed4ebcee94c9ca6b05614394cc5a2