Full title: 'Hopes, worries and expectations' experiences of pregnancy with inflammatory bowel disease: An interpretative phenomenological analysis study

Autor: Rebecca Homer-Perry, Wladyslawa Czuber-Dochan, Tiffany Wade, Satvinder Purewal, Sarah CE. Chapman, Matthew Brookes, Christian P. Selinger, Helen Steed

Publikováno v: Heliyon, Vol 10, Iss 11, Pp e31954- (2024)

Background and Aims: Inflammatory Bowel Disease (IBD) affects many women of childbearing age. High levels of voluntary childlessness and high levels of pregnancy-related fears have been reported amongst these patients in several quantitative studies.

Externí odkaz: https://doaj.org/article/18abafc1ef744b079faac337b68d4916

p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study

Autor: Martin Köbel, Eun‐Young Kang, Ashley Weir, Peter F Rambau, Cheng‐Han Lee, Gregg S Nelson, Prafull Ghatage, Nicola S Meagher, Marjorie J Riggan, Jennifer Alsop, Michael S Anglesio, Matthias W Beckmann, Christiani Bisinotto, Michelle Boisen, Jessica Boros, Alison H Brand, Angela Brooks‐Wilson, Michael E Carney, Penny Coulson, Madeleine Courtney‐Brooks, Kara L Cushing‐Haugen, Cezary Cybulski, Suha Deen, Mona A El‐Bahrawy, Esther Elishaev, Ramona Erber, Sian Fereday, AOCS Group, Anna Fischer, Simon A Gayther, Arantzazu Barquin‐Garcia, Aleksandra Gentry‐Maharaj, C Blake Gilks, Helena Gronwald, Marcel Grube, Paul R Harnett, Holly R Harris, Andreas D Hartkopf, Arndt Hartmann, Alexander Hein, Joy Hendley, Brenda Y Hernandez, Yajue Huang, Anna Jakubowska, Mercedes Jimenez‐Linan, Michael E Jones, Catherine J Kennedy, Tomasz Kluz, Jennifer M Koziak, Jaime Lesnock, Jenny Lester, Jan Lubiński, Teri A Longacre, Maria Lycke, Constantina Mateoiu, Bryan M McCauley, Valerie McGuire, Britta Ney, Alexander Olawaiye, Sandra Orsulic, Ana Osorio, Luis Paz‐Ares, Teresa Ramón y Cajal, Joseph H Rothstein, Matthias Ruebner, Minouk J Schoemaker, Mitul Shah, Raghwa Sharma, Mark E Sherman, Yurii B Shvetsov, Naveena Singh, Helen Steed, Sarah J Storr, Aline Talhouk, Nadia Traficante, Chen Wang, Alice S Whittemore, Martin Widschwendter, Lynne R Wilkens, Stacey J Winham, Javier Benitez, Andrew Berchuck, David D Bowtell, Francisco J Candido dos Reis, Ian Campbell, Linda S Cook, Anna DeFazio, Jennifer A Doherty, Peter A Fasching, Renée T Fortner, María J García, Marc T Goodman, Ellen L Goode, Jacek Gronwald, David G Huntsman, Beth Y Karlan, Linda E Kelemen, Stefan Kommoss, Nhu D Le, Stewart G Martin, Usha Menon, Francesmary Modugno, Paul DP Pharoah, Joellen M Schildkraut, Weiva Sieh, Annette Staebler, Karin Sundfeldt, Anthony J Swerdlow, Susan J Ramus, James D Brenton

Publikováno v: The Journal of Pathology: Clinical Research, Vol 9, Iss 3, Pp 208-222 (2023)

Abstract Our objective was to test whether p53 expression status is associated with survival for women diagnosed with the most common ovarian carcinoma histotypes (high‐grade serous carcinoma [HGSC], endometrioid carcinoma [EC], and clear cell carc

Externí odkaz: https://doaj.org/article/493c5874781345c8971b7e798d52a02b

The impact of treatment with bile acid sequestrants on quality of life in patients with bile acid diarrhoea

Autor: Aditi Kumar, Niall Galbraith, Hafid O. Al-Hassi, Manushri Jain, Oliver Phipps, Jeffrey Butterworth, Helen Steed, John McLaughlin, Matthew J. Brookes

Publikováno v: BMC Gastroenterology, Vol 22, Iss 1, Pp 1-11 (2022)

Abstract Background Bile acid diarrhoea (BAD) can be severely debilitating and negatively affect patients’ quality of life (QoL). We carried out a multi-centre prospective study exploring QoL outcomes in patients with BAD after treatment with coles

Externí odkaz: https://doaj.org/article/9e395c22e5a74b818491cf5f56ab2995

A single faecal bile acid stool test demonstrates potential efficacy in replacing SeHCAT testing for bile acid diarrhoea in selected patients

Autor: Aditi Kumar, Hafid O. Al-Hassi, Manushri Jain, Oliver Phipps, Clare Ford, Rousseau Gama, Helen Steed, Jeffrey Butterworth, John McLaughlin, Niall Galbraith, Matthew J. Brookes, Lauren E. Hughes

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract This study examines the validity of measuring faecal bile acids (FBA) in a single stool sample as a diagnostic tool for bile acid diarrhoea (BAD) by direct comparison to the 75selenium-homotaurocholic acid (SeHCAT) scan. A prospective observ

Externí odkaz: https://doaj.org/article/19d68fedaf0a4562a01e7e23152a03bb

Bile Acids and the Microbiome: Making Sense of This Dynamic Relationship in Their Role and Management in Crohn’s Disease

Autor: Aditi Kumar, Hafid O. Al-Hassi, Helen Steed, Oliver Phipps, Matthew J. Brookes

Publikováno v: Canadian Journal of Gastroenterology and Hepatology, Vol 2022 (2022)

Background. Bile acids help maintain the physiological balance of the gut microbiome and the integrity of the intestinal epithelial barrier. Similarly, intestinal bacteria play a major role in bile acid metabolism as they are involved in crucial biot

Externí odkaz: https://doaj.org/article/9bd736de4b574cc296161fbff52f7e84