Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Helen, Künstlinger"'
Autor:
Katja Schmitz, Hartmut Koeppen, Elke Binot, Jana Fassunke, Helen Künstlinger, Michaela A Ihle, Carina Heydt, Eva Wardelmann, Reinhard Büttner, Sabine Merkelbach-Bruse, Josef Rüschoff, Hans-Ulrich Schildhaus
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120079 (2015)
Soft tissue sarcomas are a heterogeneous group of tumors with many different subtypes. In 2014 an estimated 12,020 newly diagnosed cases and 4,740 soft tissue sarcoma related deaths can be expected in the United States. Many soft tissue sarcomas are
Externí odkaz:
https://doaj.org/article/108887431b474771afe0a4e5f969b485
Autor:
Carina Heydt, Jana Fassunke, Helen Künstlinger, Michaela Angelika Ihle, Katharina König, Lukas Carl Heukamp, Hans-Ulrich Schildhaus, Margarete Odenthal, Reinhard Büttner, Sabine Merkelbach-Bruse
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104566 (2014)
Over the last years, massively parallel sequencing has rapidly evolved and has now transitioned into molecular pathology routine laboratories. It is an attractive platform for analysing multiple genes at the same time with very little input material.
Externí odkaz:
https://doaj.org/article/1b0a555199ba457291e8cd96ba50cc96
Autor:
Matthias Scheffler, Marc Bos, Kerstin Albus, Frank Ueckeroth, Jana Fassunke, Jürgen Wolf, Winfried Randerath, Thomas Zander, Karin Töpelt, Monika Serke, Britta Kaminsky, Walburga Engel-Riedel, Reinhard Büttner, Ulrich Gerigk, Carolin Becker, Michaela Angelika Ihle, Masyar Gardizi, Sabine Merkelbach-Bruse, Sebastian Michels, Erich Stoelben, Lukas C. Heukamp, Carina Heydt, Lucia Nogova, Martin Hellmich, Wolfgang Schulte, Katharina König, Jens Panse, Helen Künstlinger, Yon-Dschun Ko
Publikováno v:
Oncotarget
Scopus-Elsevier
Oncotarget 6(2), 1315-1326 (2015). doi:10.18632/oncotarget.2834
Scopus-Elsevier
Oncotarget 6(2), 1315-1326 (2015). doi:10.18632/oncotarget.2834
Oncotarget 6(2), 1315-1326 (2015). doi:10.18632/oncotarget.2834
Published by Impact Journals LLC, [S.l.]
Published by Impact Journals LLC, [S.l.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da352d4f268b196b3c55c33dc0c7da3
http://europepmc.org/articles/PMC4359235
http://europepmc.org/articles/PMC4359235
Autor:
Jens Mittler, Wolfgang Hartmann, Peter Reichardt, Helen Künstlinger, Sebastian Huss, Reinhard Büttner, Sabine Merkelbach-Bruse, Elke Binot, Michaela Angelika Kleine, Peter Hohenberger, Heike Loeser, Eva Wardelmann, Hans-Ulrich Schildhaus
Publikováno v:
American Journal of Surgical Pathology. 37:1648-1659
KIT exon 9 mutations in gastrointestinal stromal tumors (GISTs) are highly relevant and have direct therapeutic implications. In this context, we established and validated a fast and sensitive high-resolution melting assay. Analyzing 126 primary and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d3e4f2dec05eab03bab43bce230f47
https://doi.org/10.1097/pas.0b013e3182986b88
https://doi.org/10.1097/pas.0b013e3182986b88
Autor:
Elke Binot, Helen Künstlinger, Thomas Rüdiger, Sebastian Huss, Jens Mittler, Michaela Angelika Kleine, Reinhard Büttner, Hans-Ulrich Schildhaus, Wolfgang Hartmann, Eva Wardelmann, Sabine Merkelbach-Bruse
Publikováno v:
Modern Pathology
About 10-15% of gastrointestinal stromal tumors (GISTs) carry wild-type sequences in all hot spots of KIT and platelet-derived growth factor receptor alpha (PDGFRA) (wt-GISTs). These tumors are currently defined by having no mutations in exons 9, 11,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c657c4b6912415180f0baa0e9eadb031
http://europepmc.org/articles/PMC3701292
http://europepmc.org/articles/PMC3701292
Autor:
Michaela Angelika Kleine, Sebastian Huss, Peter Hohenberger, Helen Künstlinger, Eva Wardelmann, Jens Mittler, Elke Binot, Julia Nehles, Sabine Merkelbach-Bruse, Reinhard Buettner, Wolfgang Hartmann, Hans-Ulrich Schildhaus
Publikováno v:
Histopathology. 62:294-304
Aims and methods: Desmoid-type fibromatosis (desmoid) is a fibroblastic tumour that shows locally aggressive growth. Mesenteric desmoid is a rare lesion that shares morphological and biological features with fibromatoses occurring in the abdominal wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1536956a717e8deec9e621b7792f689c
https://doi.org/10.1111/j.1365-2559.2012.04355.x
https://doi.org/10.1111/j.1365-2559.2012.04355.x
Autor:
Helen Künstlinger, Alexander Quaas, Sabine Merkelbach-Bruse, Elfriede Bollschweiler, Peter P. Grimminger, Jeannine Meinrath, Maike Michalk, Michael Kloth, Arnulf H. Hölscher, Uta Drebber, Ulrike Koitzsch, Margarete Odenthal, Wolfgang Hartmann
Publikováno v:
Oncology reports. 35(4)
Esophageal cancer (EC) is one of the most common malignancies diagnosed in the Western world with an increasing incidence noted for esophageal adenocarcinoma (EAC). Despite improvements in staging, surgical procedures and postoperative treatments, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62e3917a02e9df40ec063578a3d3957
https://pubmed.ncbi.nlm.nih.gov/26796597
https://pubmed.ncbi.nlm.nih.gov/26796597
Autor:
Christian Grohé, Jürgen Wolf, Lukas C. Heukamp, Walburga Engel-Riedel, Oliver Gautschi, Michaela Angelika Ihle, Lukas Bubendorf, Clemens Müller-Naendrup, Franziska Aebersold, Anne Adams, Jana Fassunke, Christian Mattonet, Winfried Randerath, Rebecca Hein, Stefan Krüger, Georg Pall, Matthias Scheffler, Joachim Diebold, Hans-Ulrich Schildhaus, Helen Künstlinger, Sabine Merkelbach-Bruse, Sebastian Michels, Ullrich Graeven, Carina Heydt, Heike Lüders, Monika Serke, Wolfgang Hartmann, Andreas H. Scheel, Rieke Fischer, Britta Kaminsky, Susanne Schulze-Olden, Ulrich Gerigk, Karl-Otto Kambartel, Sacha I. Rothschild, Anne M. Schultheis, Wolfgang Schulte, Lucia Nogova, Reinhard Büttner, Andreas Draube
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 11(1)
Introduction Rearrangements of RET are rare oncogenic events in patients with non–small cell lung cancer (NSCLC). While the characterization of Asian patients suggests a predominance of nonsmokers of young age in this genetically defined lung cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a12bbb32c9e17e886630d2599da6138
https://pubmed.ncbi.nlm.nih.gov/26762747
https://pubmed.ncbi.nlm.nih.gov/26762747
Autor:
Ursula Rommerscheidt-Fuss, Jürgen Wolf, Sven-Ernö Bikár, Katharina König, Lucia Nogova, Marc Bos, Carina Heydt, Frauke Leenders, Peter Nürnberg, Claudia Vollbrecht, Martin L. Sos, Margarete Odenthal, Kerstin Becker, Frank Ueckeroth, Michael Kloth, Sabine Merkelbach-Bruse, Lukas C. Heukamp, Matthias Scheffler, Alexandra Florin, Janine Altmüller, Kerstin Albus, William J. Geese, Lewis C. Strauss, Yon-Dschun Ko, Reinhard Buettner, Ulrich Gerigk, Katrin Stamm, Masyar Gardizi, Helen Künstlinger, Jana Fassunke, Thomas Zander, Michaela Angelika Ihle, Thomas Henkel, Lydia Meder, Martin Peifer
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 10(7)
Introduction: The Network Genomic Medicine Lung Cancer was set up to rapidly translate scientific advances into early clinical trials of targeted therapies in lung cancer performing molecular analyses of more than 3500 patients annually. Because sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08e2aad5b9a0c2c262d948d6b64b9c7
https://pubmed.ncbi.nlm.nih.gov/26102443
https://pubmed.ncbi.nlm.nih.gov/26102443
Autor:
Reinhard Büttner, Sabine Merkelbach-Bruse, Elke Binot, Josef Rüschoff, Hans-Ulrich Schildhaus, Hartmut Koeppen, Katja Schmitz, Eva Wardelmann, Jana Fassunke, Carina Heydt, Michaela Angelika Ihle, Helen Künstlinger
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120079 (2015)
PLoS ONE
PLoS ONE
Soft tissue sarcomas are a heterogeneous group of tumors with many different subtypes. In 2014 an estimated 12,020 newly diagnosed cases and 4,740 soft tissue sarcoma related deaths can be expected in the United States. Many soft tissue sarcomas are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4333512e50846297afd42fc6d4969bb
http://europepmc.org/articles/PMC4386816?pdf=render
http://europepmc.org/articles/PMC4386816?pdf=render