Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Heleen de-Jong"'
Autor:
Daan Sondag, Luuk Maartense, Heleen de Jong, Frank F. J. de Kleijne, Kimberly M. Bonger, Dennis W. P. M. Löwik, Thomas J. Boltje, Jan Dommerholt, Paul B. White, Daniel Blanco‐Ania, Floris P. J. T. Rutjes
Publikováno v:
Chemistry : a European Journal, 29, 6, pp. 1-9
Chemistry : a European Journal, 29, 1-9
Chemistry : a European Journal, 29, 1-9
The click reaction between a functionalized trans-cyclooctene (TCO) and a tetrazine (Tz) is a compelling method for bioorthogonal conjugation in combination with payload releasing capabilities. However, the synthesis of difunctionalized TCOs remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51fe2d06ff1284e8ed85a753644bbf6
https://pubmed.ncbi.nlm.nih.gov/36478614
https://pubmed.ncbi.nlm.nih.gov/36478614
Autor:
Daan Sondag, Luuk Maartense, Heleen de Jong, Frank de Kleijne, Kim Bonger, Dennis Lowik, Thomas Boltje, Jan Dommerholt, Paul White, Daniel Blanco-Ania, Floris Rutjes
The click reaction between a functionalized trans-cyclooctene (TCO) and a tetrazine is a compelling method for bioorthogonal conjugation in combination with payload releasing capabilities. However, the synthesis of difunctionalized TCOs remains chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a212e20dfce84639d07837ab6a4a144
https://doi.org/10.26434/chemrxiv-2022-klj4d
https://doi.org/10.26434/chemrxiv-2022-klj4d
Autor:
Thomas J. Boltje, Heleen de Jong, Sam J. Moons, Eline A. Visser, Suzanne B. P. E. Timmermans, Christian Büll
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry, 297, 1-19
Journal of Biological Chemistry, 297, 2, pp. 1-19
Visser, E A, Moons, S J, Timmermans, S B P E, de Jong, H, Boltje, T J & Büll, C 2021, ' Sialic acid O-acetylation : From biosynthesis to roles in health and disease ', Journal of Biological Chemistry, vol. 297, no. 2, 100906, pp. 1-19 . https://doi.org/10.1016/j.jbc.2021.100906
Journal of Biological Chemistry, 297, 1-19
Journal of Biological Chemistry, 297, 2, pp. 1-19
Visser, E A, Moons, S J, Timmermans, S B P E, de Jong, H, Boltje, T J & Büll, C 2021, ' Sialic acid O-acetylation : From biosynthesis to roles in health and disease ', Journal of Biological Chemistry, vol. 297, no. 2, 100906, pp. 1-19 . https://doi.org/10.1016/j.jbc.2021.100906
Sialic acids are nine-carbon sugars that frequently cap glycans at the cell surface in cells of vertebrates as well as cells of certain types of invertebrates and bacteria. The nine-carbon backbone of sialic acids can undergo extensive enzymatic modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704561863100cd1be53c62370b397510
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/245797
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/245797
Publikováno v:
RSC Chemical Biology
An important hurdle for the intracellular delivery of large cargo is the cellular membrane, which protects the cell from exogenous substances. Cell-penetrating peptides (CPPs) can cross this barrier but their use as drug delivery vehicles is hampered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f46fe6699b6f89316d1ad225392bfb4
https://doi.org/10.1039/d0cb00114g
https://doi.org/10.1039/d0cb00114g
Publikováno v:
ACS applied bio materials. 2(7)
Hydrogels are water-saturated polymer networks and extensively used in drug delivery, tissue repair engineering, and cell cultures. For encapsulation of drugs or cells, the possibility to form hydrogels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49d27f863ef699c8df0ee45fe19dbcab
https://pubmed.ncbi.nlm.nih.gov/35030820
https://pubmed.ncbi.nlm.nih.gov/35030820
Autor:
Francesco Bavo, Heleen de-Jong, Jonas Petersen, Christina Birkedahl Falk-Petersen, Rebekka Löffler, Emma Sparrow, Frederik Rostrup, Jannik Nicklas Eliasen, Kristine S. Wilhelmsen, Kasper Barslund, Christoffer Bundgaard, Birgitte Nielsen, Uffe Kristiansen, Petrine Wellendorph, Yury Bogdanov, Bente Frølund
The 3,9-diazaspiro[5.5]undecane-based compounds 2027 and 018 have previously been reported to be potent competitive γ-aminobutyric acid type A receptor (GABAAR) antagonists showing low cellular membrane permeability. Given the emerging peripheral ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1b8597a5aeec1385cffce2213ce18f
https://eprints.soton.ac.uk/454543/
https://eprints.soton.ac.uk/454543/
Publikováno v:
ACS Applied Bio Materials, 2, 7, pp. 2862-2871
ACS Applied Bio Materials, 2, 2862-2871
ACS Applied Bio Materials, 2, 2862-2871
Hydrogels are water-saturated polymer networks and extensively used in drug delivery, tissue repair engineering, and cell cultures. For encapsulation of drugs or cells, the possibility to form hydrogels in situ is very much desired. This can be achie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3cbd2376aa9d03edf4d894a428d2f9