Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Heleen Verschueren"'
Autor:
Nik Sol, Sjors G.J.G. in ‘t Veld, Adrienne Vancura, Maud Tjerkstra, Cyra Leurs, François Rustenburg, Pepijn Schellen, Heleen Verschueren, Edward Post, Kenn Zwaan, Jip Ramaker, Laurine E. Wedekind, Jihane Tannous, Bauke Ylstra, Joep Killestein, Farrah Mateen, Sander Idema, Philip C. de Witt Hamer, Anna C. Navis, William P.J. Leenders, Ann Hoeben, Bastiaan Moraal, David P. Noske, W. Peter Vandertop, R. Jonas A. Nilsson, Bakhos A. Tannous, Pieter Wesseling, Jaap C. Reijneveld, Myron G. Best, Thomas Wurdinger
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101- (2020)
Summary: Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA pro
Externí odkaz:
https://doaj.org/article/3c63ceb85e20460e8535824c45ce6bd6
Autor:
Chantal Scheepbouwer, Ernesto Aparicio-Puerta, Cristina Gomez-Martin, Heleen Verschueren, Monique van Eijndhoven, Laurine E. Wedekind, Stavros Giannoukakos, Nathalie Hijmering, Lisa Gasparotto, Hilde T. van der Galien, Roos S. van Rijn, Eleonora Aronica, Robby Kibbelaar, Vivi M. Heine, Pieter Wesseling, David P. Noske, W. Peter Vandertop, Daphne de Jong, D. Michiel Pegtel, Michael Hackenberg, Tom Wurdinger, Alan Gerber, Danijela Koppers-Lalic
Publikováno v:
Genes & development, 37(5-6), 243-257. Cold Spring Harbor Laboratory Press
Scheepbouwer, C, Aparicio-Puerta, E, Gomez-Martin, C, Verschueren, H, van Eijndhoven, M, Wedekind, L E, Giannoukakos, S, Hijmering, N, Gasparotto, L, van der Galien, H T, van Rijn, R S, Aronica, E, Kibbelaar, R, Heine, V M, Wesseling, P, Noske, D P, Vandertop, W P, de Jong, D, Pegtel, D M, Hackenberg, M, Wurdinger, T, Gerber, A & Koppers-Lalic, D 2023, ' ALL-tRNAseq enables robust tRNA profiling in tissue samples ', Genes and Development, vol. 37, no. 5-6, pp. 243-257 . https://doi.org/10.1101/gad.350233.122
Genes and Development, 37(5-6), 243-257. Cold Spring Harbor Laboratory Press
Scheepbouwer, C, Aparicio-Puerta, E, Gomez-Martin, C, Verschueren, H, van Eijndhoven, M, Wedekind, L E, Giannoukakos, S, Hijmering, N, Gasparotto, L, van der Galien, H T, van Rijn, R S, Aronica, E, Kibbelaar, R, Heine, V M, Wesseling, P, Noske, D P, Vandertop, W P, de Jong, D, Pegtel, D M, Hackenberg, M, Wurdinger, T, Gerber, A & Koppers-Lalic, D 2023, ' ALL-tRNAseq enables robust tRNA profiling in tissue samples ', Genes and Development, vol. 37, no. 5-6, pp. 243-257 . https://doi.org/10.1101/gad.350233.122
Genes and Development, 37(5-6), 243-257. Cold Spring Harbor Laboratory Press
Transfer RNAs (tRNAs) are small adaptor RNAs essential for mRNA translation. Alterations in the cellular tRNA population can directly affect mRNA decoding rates and translational efficiency during cancer development and progression. To evaluate chang
Autor:
François Rustenburg, Cyra E. Leurs, Bakhos A. Tannous, Maud Tjerkstra, Farrah J. Mateen, Sander Idema, Bauke Ylstra, W. Peter Vandertop, Laurine E. Wedekind, Nik Sol, Adrienne Vancura, Edward Post, William P.J. Leenders, R. Jonas A. Nilsson, B. Moraal, Jip Ramaker, Anna C. Navis, Kenn Zwaan, Ann Hoeben, Sjors G J G In 't Veld, Jihane Tannous, Joep Killestein, Philip C. De Witt Hamer, Jaap C. Reijneveld, Thomas Wurdinger, Heleen Verschueren, Pieter Wesseling, Pepijn Schellen, David P. Noske, Myron G. Best
Publikováno v:
Cell Reports Medicine, 1(7):100101. Cell Press
Cell reports. Medicine, 1(7):100101. Cell Press
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101-(2020)
Cell Reports Medicine, 1, 7
Cell Reports. Medicine
Cell Reports Medicine, 1
Sol, N, in ‘t Veld, S G J G, Vancura, A, Tjerkstra, M, Leurs, C, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Zwaan, K, Ramaker, J, Wedekind, L E, Tannous, J, Ylstra, B, Killestein, J, Mateen, F, Idema, S, de Witt Hamer, P C, Navis, A C, Leenders, W P J, Hoeben, A, Moraal, B, Noske, D P, Vandertop, W P, Nilsson, R J A, Tannous, B A, Wesseling, P, Reijneveld, J C, Best, M G & Wurdinger, T 2020, ' Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma ', Cell reports. Medicine, vol. 1, no. 7, 100101, pp. 100101 . https://doi.org/10.1016/j.xcrm.2020.100101, https://doi.org/10.1016/j.xcrm.2020.100101
Cell reports. Medicine, 1(7):100101. Cell Press
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101-(2020)
Cell Reports Medicine, 1, 7
Cell Reports. Medicine
Cell Reports Medicine, 1
Sol, N, in ‘t Veld, S G J G, Vancura, A, Tjerkstra, M, Leurs, C, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Zwaan, K, Ramaker, J, Wedekind, L E, Tannous, J, Ylstra, B, Killestein, J, Mateen, F, Idema, S, de Witt Hamer, P C, Navis, A C, Leenders, W P J, Hoeben, A, Moraal, B, Noske, D P, Vandertop, W P, Nilsson, R J A, Tannous, B A, Wesseling, P, Reijneveld, J C, Best, M G & Wurdinger, T 2020, ' Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma ', Cell reports. Medicine, vol. 1, no. 7, 100101, pp. 100101 . https://doi.org/10.1016/j.xcrm.2020.100101, https://doi.org/10.1016/j.xcrm.2020.100101
Summary Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA prof
Autor:
Pieter Wesseling, Stefanie Kellner, Ernesto L. Aparicio, Chantal Scheepbouwer, Laurine Wedekind, Kayla Borland, Danijela Koppers-Lalic, Mathilde C.M. Kouwenhoven, Branko Misovic, Peter Vandertop, Thomas Wurdinger, David P. Noske, Michael Hackenberg, Heleen Verschueren, Jip Ramaker
Publikováno v:
Neuro Oncol
BACKGROUND Diffuse lower grade gliomas (LGGs) are generally slow growing primary central nervous system tumors that occur in early adult life. The prevalence of isocitrate dehydrogenase (IDH) mutations is high in LGG, and induces excess production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f3d9c905af757d49e927a6446560cd
https://europepmc.org/articles/PMC6847647/
https://europepmc.org/articles/PMC6847647/
Autor:
Nik Sol, Jaap C. Reijneveld, Pepijn Schellen, Thomas Wurdinger, Henk Verheuk, Myron G. Best, Pieter Wesseling, François Rustenburg, Heleen Verschueren, Edward Post, Bakhos A. Tannous, Davis Noske, Bauke Ylstra, Sjors G J G In 't Veld, Jonas Nilsson
INTRODUCTION: Blood-based liquid biopsies are a potential approach for leveraging clinical cancer diagnostics and patients' treatment. However, so far, diagnostic, prognostic, predictive, and monitoring biomarkers for patients with diffuse glioma are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aeca12b2eeab92ef28b73cdaaa9b8f1
https://europepmc.org/articles/PMC4638720/
https://europepmc.org/articles/PMC4638720/
Autor:
Heleen Verschueren, Myron G. Best, Thomas Wurdinger, Maarten F. Bijlsma, Elisa Giovannetti, Laura L. Meijer, Ewoud van der Lelij, Marc G. Besselink, Niccola Funel, Geert Kazemier, Giulia Mantini, Ingrid Garajová, Nik Sol, François Rustenburg, Sjors G. J. G. In ‘t Veld, Tessa Y S Le Large
Publikováno v:
Cancer Research. 78:2596-2596
Pancreatic ductal adenocarcinoma (PDAC) is often diagnosed at advanced disease stages and invasive procedures are needed to confirm diagnosis. Innovative liquid biopsy-based approaches are warranted to diagnose early stages and prevent unnecessary tr
Autor:
Bart A. Westerman, Pepijn Schellen, Nik Sol, Heleen Verschueren, Thomas Wurdinger, Egbert F. Smit, Jihane Tannous, Najim Ameziane, Pieter Wesseling, Jaap C. Reijneveld, Myron G. Best, Henk M.W. Verheul, Jan Koster, Josephine C. Dorsman, Bakhos A. Tannous, David P. Noske, François Rustenburg, Edward Post, R. Jonas A. Nilsson, Bauke Ylstra, Irsan E. Kooi
Publikováno v:
Cancer Cell, 28(5), 666-676. Cell Press
Cancer Cell, 28(5), 666. Cell Press
Cancer Cell, 28, 666-76
Cancer cell, 28(5), 666-676. Cell Press
Cancer Cell
Cancer Cell, 28, 5, pp. 666-76
Best, M G, Sol, N, Kooi, E I, Tannous, J, Westerman, A, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Koster, J, Ylstra, B, Ameziane, N, Dorsman, J, Smit, E F, Verheul, H M, Noske, D P, Reijneveld, J C, Nilsson, R J A, Tannous, B A, Wesseling, P & Wurdinger, T 2015, ' RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics ', Cancer Cell, vol. 28, no. 5, pp. 666-676 . https://doi.org/10.1016/j.ccell.2015.09.018
Cancer Cell, 28(5), 666. Cell Press
Cancer Cell, 28, 666-76
Cancer cell, 28(5), 666-676. Cell Press
Cancer Cell
Cancer Cell, 28, 5, pp. 666-76
Best, M G, Sol, N, Kooi, E I, Tannous, J, Westerman, A, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Koster, J, Ylstra, B, Ameziane, N, Dorsman, J, Smit, E F, Verheul, H M, Noske, D P, Reijneveld, J C, Nilsson, R J A, Tannous, B A, Wesseling, P & Wurdinger, T 2015, ' RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics ', Cancer Cell, vol. 28, no. 5, pp. 666-676 . https://doi.org/10.1016/j.ccell.2015.09.018
Summary Tumor-educated blood platelets (TEPs) are implicated as central players in the systemic and local responses to tumor growth, thereby altering their RNA profile. We determined the diagnostic potential of TEPs by mRNA sequencing of 283 platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e6f8b66ce2ad8929b91af1171d0d1e
https://research.vumc.nl/en/publications/3cfca64c-e759-4641-adbe-90d7185170d1
https://research.vumc.nl/en/publications/3cfca64c-e759-4641-adbe-90d7185170d1
Autor:
Anna E. Huis In ‘t Veld, Michel M van den Heuvel, Pieter Wesseling, Niki Karachaliou, Nik Sol, Aniko V. Fejes, Adrianus J. de Langen, Michal Heger, Pepijn Schellen, Laura L. Meijer, Jilian D. Schoonhoven, Hanne Meijers-Heijboer, Sjors G J G In 't Veld, Bakhos A. Tannous, Irsan E. Kooi, Jose Gomez-Arroyo, Jillian Bracht, Rafael Rosell, Anna Larissa N. Niemeijer, Joep Killestein, Mirte Muller, Michelle Esenkbrink, Egbert F. Smit, Imo E. Hoefer, Jihane Tannous, Elizabeth Lee-Lewandrowski, Geert Kazemier, Heleen Verschueren, Francesca Favaro, Sander Idema, Bauke Ylstra, François Rustenburg, Rolf T. Urbanus, W. Peter Vandertop, Laurine E. Wedekind, Christine Mannhalter, Harm Jan Bogaard, Cyra E. Leurs, Adrienne Vancura, Lee Ann Tjon Kon Fat, Edward Post, Leon J Wils, Myron G. Best, Saskia C.A. de Jager, R. Jonas A. Nilsson, Jaap C. Reijneveld, Gerard Pasterkamp, Tessa Y S Le Large, Kent B. Lewandrowski, Elisa Giovannetti, Daan van den Broek, David P. Noske, Thomas Wurdinger
Publikováno v:
Cancer Cell, 32(2), 238-252.e9. Cell Press
Cancer Cell
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Cancer Cell, 32, 238-252.e9
Best, M G, Sol, N, In ‘t Veld, S G J G, Vancura, A, Muller, M, Niemeijer, A L N, Fejes, A V, Tjon Kon Fat, L A, Huis In ‘t Veld, A E, Leurs, C, Le Large, T Y, Meijer, L L, Kooi, I E, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Wedekind, L E, Bracht, J, Esenkbrink, M, Wils, L, Favaro, F, Schoonhoven, J D, Tannous, J, Meijers-Heijboer, H, Kazemier, G, Giovannetti, E, Reijneveld, J C, Idema, S, Killestein, J, Heger, M, de Jager, S C, Urbanus, R T, Hoefer, I E, Pasterkamp, G, Mannhalter, C, Gomez-Arroyo, J, Bogaard, H J, Noske, D P, Vandertop, W P, van den Broek, D, Ylstra, B, Nilsson, R J A, Wesseling, P, Karachaliou, N, Rosell, R, Lee-Lewandrowski, E, Lewandrowski, K B, Tannous, B A, de Langen, A J, Smit, E F, van den Heuvel, M M & Wurdinger, T 2017, ' Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets ', Cancer Cell, vol. 32, no. 2, pp. 238-252.e9 . https://doi.org/10.1016/j.ccell.2017.07.004
Cancer Cell, 32(2), 238. Cell Press
Cancer Cell, 32, 2, pp. 238-252.e9
Cancer cell, 32(2), 238-252.e9. Cell Press
Cancer Cell
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Cancer Cell, 32, 238-252.e9
Best, M G, Sol, N, In ‘t Veld, S G J G, Vancura, A, Muller, M, Niemeijer, A L N, Fejes, A V, Tjon Kon Fat, L A, Huis In ‘t Veld, A E, Leurs, C, Le Large, T Y, Meijer, L L, Kooi, I E, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Wedekind, L E, Bracht, J, Esenkbrink, M, Wils, L, Favaro, F, Schoonhoven, J D, Tannous, J, Meijers-Heijboer, H, Kazemier, G, Giovannetti, E, Reijneveld, J C, Idema, S, Killestein, J, Heger, M, de Jager, S C, Urbanus, R T, Hoefer, I E, Pasterkamp, G, Mannhalter, C, Gomez-Arroyo, J, Bogaard, H J, Noske, D P, Vandertop, W P, van den Broek, D, Ylstra, B, Nilsson, R J A, Wesseling, P, Karachaliou, N, Rosell, R, Lee-Lewandrowski, E, Lewandrowski, K B, Tannous, B A, de Langen, A J, Smit, E F, van den Heuvel, M M & Wurdinger, T 2017, ' Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets ', Cancer Cell, vol. 32, no. 2, pp. 238-252.e9 . https://doi.org/10.1016/j.ccell.2017.07.004
Cancer Cell, 32(2), 238. Cell Press
Cancer Cell, 32, 2, pp. 238-252.e9
Cancer cell, 32(2), 238-252.e9. Cell Press
Summary Blood-based liquid biopsies, including tumor-educated blood platelets (TEPs), have emerged as promising biomarker sources for non-invasive detection of cancer. Here we demonstrate that particle-swarm optimization (PSO)-enhanced algorithms ena