Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Heleen M. Kool"'
Publikováno v:
European Respiratory Review, Vol 27, Iss 147 (2018)
Congenital diaphragmatic hernia (CDH) is a rare congenital anomaly characterised by a diaphragmatic defect, persistent pulmonary hypertension (PH) and lung hypoplasia. The relative contribution of these three elements can vary considerably in individ
Externí odkaz:
https://doaj.org/article/f6971bdc10ae4c7385ff1297f4378750
Autor:
Ihsan Chrifi, Robbert J. Rottier, Inge de Laat, Heleen M. Kool, Anne Boerema-de Munck, Ismé de Kleer, Caroline Cheng, Dick Tibboel, Gert-Jan Kremers, Petra E. Bürgisser, Gabriela G Edel, Wiggert A. van Cappellen
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology, 317(3), L317-L331. American Physiological Society
The mortality and morbidity of patients with congenital diaphragmatic hernia (CDH) is primarily caused by treatment-resistant, persistent pulmonary hypertension. Structural vascular changes, exemplified by extensive muscularization, are already prese
Autor:
Oleh Dzyubachyk, Robbert J. Rottier, Petra E. Bürgisser, Rene M. H. Wijnen, Marjon Buscop-van Kempen, Joost van Rosmalen, Heleen M. Kool, Koji Nagata, Daphne S. Mous, Anne Boerema-de Munck, Dick Tibboel
Publikováno v:
AJP-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, 315(2), L276-L285. American Physiological Society
AJP-Lung Cellular and Molecular Physiology, 315(2), L276-L285
American Journal of Physiology-Lung Cellular and Molecular Physiology, 315(2), L276-L285. American Physiological Society
AJP-Lung Cellular and Molecular Physiology, 315(2), L276-L285
Patients with congenital diaphragmatic hernia (CDH) often suffer from severe pulmonary hypertension, and the choice of current vasodilator therapy is mostly based on trial and error. Because pulmonary vascular abnormalities are already present early
Autor:
Jiayi Pei, Caroline Cheng, Heleen M. Kool, Maarten M. Brandt, Dirk J. Duncker, Laura Louzao-Martinez, Petra E. Bürgisser, Christian G. M. van Dijk, Marianne C. Verhaar, Robbert J. Rottier, Ihsan Chrifi
Publikováno v:
Angiogenesis, 21(4), 805-821. Springer Netherlands
Angiogenesis
Angiogenesis
Aims Formation of a functional vascular system is essential and its formation is a highly regulated process initiated during embryogenesis, which continues to play important roles throughout life in both health and disease. In previous studies, Fzd5
Publikováno v:
European Respiratory Review, 27(147):Unsp 170104. European Respiratory Society
European Respiratory Review, Vol 27, Iss 147 (2018)
European Respiratory Review, Vol 27, Iss 147 (2018)
Congenital diaphragmatic hernia (CDH) is a rare congenital anomaly characterised by a diaphragmatic defect, persistent pulmonary hypertension (PH) and lung hypoplasia. The relative contribution of these three elements can vary considerably in individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbc188fb1db5042fd111d95df2fffad
https://pure.eur.nl/en/publications/aead64eb-74ef-4696-ba46-257a37222bb0
https://pure.eur.nl/en/publications/aead64eb-74ef-4696-ba46-257a37222bb0
Publikováno v:
Birth Defects Research Part C: Embryo Today: Reviews. 102:343-358
Pulmonary vascular diseases of the newborn comprise a wide range of pathological conditions with developmental abnormalities in the pulmonary vasculature. Clinically, pulmonary arterial hypertension (PH) is characterized by persistent increased resis
Autor:
Jiayi Pei, Dirk J. Duncker, Heleen M. Kool, Ihsan Chrifi, Maarten M. Brandt, Caroline Cheng, Cgm Van Dijk, Robbert J. Rottier, Marianne C. Verhaar, Laura Louzao-Martinez
Publikováno v:
Cardiovascular Research. 114:S91-S92
Autor:
Robbert J. Rottier, Heleen M. Kool, Esther van Mastrigt, Ismé de Kleer, Chris van Dijk, Rudi W. Hendriks, Irwin K.M. Reiss, Caroline Cheng, Johan C. de Jongste, Janneke N. Samsom, Marielle W. Pijnenburg
Publikováno v:
7.5 Neonatology and Paediatric Intensive Care.
Bronchopulmonary dysplasia (BPD) is characterized by abnormal alveolar septation and microvascular development. Certain types of monocytes and macrophages have been implicated in epithelial growth and angiogenesis, while others play a role in immune
Autor:
Rene M. H. Wijnen, Oleh Dzyubachyk, Marjon Buscop-van Kempen, Robbert J. Rottier, Heleen M. Kool, Daphne S. Mous, Anton H. J. Koning, Dick Tibboel
Publikováno v:
AJP-Lung Cellular and Molecular Physiology, 311(4), L734-L742
American Journal of Physiology-Lung Cellular and Molecular Physiology, 311(4), L734-L742. American Physiological Society
American Journal of Physiology-Lung Cellular and Molecular Physiology, 311(4), L734-L742. American Physiological Society
Patients with congenital diaphragmatic hernia (CDH) suffer from severe pulmonary hypertension attributable to altered development of the pulmonary vasculature, which is often resistant to vasodilator therapy. Present treatment starts postnatally even
Autor:
Rene M. H. Wijnen, Anne Boerema-de Munck, Kim Schilders, Dick Tibboel, Robbert J. Rottier, Joshua K. Ochieng, Marjon Buscop-van Kempen, Heleen M. Kool, Frank Grosveld
Publikováno v:
PLoS One (print), 9(9). Public Library of Science
PLoS ONE, Vol 9, Iss 9, p e107248 (2014)
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e107248 (2014)
PLoS ONE
The adult lung contains several distinct stem cells, although their properties and full potential are still being sorted out. We previously showed that ectopic Sox2 expression in the developing lung manipulated the fate of differentiating cells. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ce638bfb779c20c79eb15825923368
https://pure.eur.nl/en/publications/354be516-dfbd-47ca-9937-848a5f78267c
https://pure.eur.nl/en/publications/354be516-dfbd-47ca-9937-848a5f78267c