Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Heleen H Van Acker"'
Autor:
Sébastien Anguille, Heleen H Van Acker, Johan Van den Bergh, Yannick Willemen, Herman Goossens, Viggo F Van Tendeloo, Evelien L Smits, Zwi N Berneman, Eva Lion
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0123340 (2015)
The contribution of natural killer (NK) cells to the treatment efficacy of dendritic cell (DC)-based cancer vaccines is being increasingly recognized. Much current efforts to optimize this form of immunotherapy are therefore geared towards harnessing
Externí odkaz:
https://doaj.org/article/478770b57fd444edb7f4eee55755d6b9
Autor:
Marijke Timmers, Gils Roex, Yuedi Wang, Diana Campillo-Davo, Viggo F. I. Van Tendeloo, Yiwei Chu, Zwi N. Berneman, Feifei Luo, Heleen H. Van Acker, Sébastien Anguille
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Chimeric antigen receptor (CAR)-modified T cell therapy is a rapidly emerging immunotherapeutic approach that is revolutionizing cancer treatment. The impressive clinical results obtained with CAR-T cell therapy in patients with acute lymphoblastic l
Externí odkaz:
https://doaj.org/article/49a4a6c44b2845dd97520781fda0d3e9
Autor:
Heleen H. Van Acker, Sébastien Anguille, Yannick Willemen, Johan M. Van den Bergh, Zwi N. Berneman, Eva Lion, Evelien L. Smits, Viggo F. Van Tendeloo
Publikováno v:
Journal of Hematology & Oncology, Vol 9, Iss 1, Pp 1-13 (2016)
Abstract Background Adoptive immunotherapy is gaining momentum to fight malignancies, whereby γδ T cells have received recent attention as an alternative cell source as to natural killer cells and αβ T cells. The advent of γδ T cells is largely
Externí odkaz:
https://doaj.org/article/78513684ceb64217ab35ff0dd5af55bf
Autor:
Massimiliano Mazzone, Oliver Bechter, Bruno M. Costa, Mario Di Matteo, Jean-Christophe Marine, Luca Tamagnone, Véronique Flamand, Abhishek D. Garg, Arnaud Köhler, Roberta Mastrantonio, Yannick Van Herck, Sarah Trusso Cafarello, Jens Serneels, Ewout Landeloos, Heleen H. Van Acker, Silvia Rivis, Ana I. Oliveira, Ward Celus
Supplementary Data from Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e50aeb16cd93992820fbd1235b11217
https://doi.org/10.1158/2326-6066.22544834
https://doi.org/10.1158/2326-6066.22544834
Autor:
Heleen H. Van Acker, Sébastien Anguille, Hans De Reu, Zwi N. Berneman, Evelien L. Smits, Viggo F. Van Tendeloo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Dendritic cell (DC) vaccination can be an effective post-remission therapy for acute myeloid leukemia (AML). Yet, current DC vaccines do not encompass the ideal stimulatory triggers for innate gamma delta (γδ) T cell anti-tumor activity. Promoting
Externí odkaz:
https://doaj.org/article/ac2662fbd1d4484f89909cd52dfe0ef5
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Over the past years, the phenotypic and functional boundaries distinguishing the main cell subsets of the immune system have become increasingly blurred. In this respect, CD56 (also known as neural cell adhesion molecule) is a very good example. CD56
Externí odkaz:
https://doaj.org/article/c0319c7c7e1f4b3bb04eb0b3ecc565f6
Autor:
Thomas J. van Ee, Heleen H. Van Acker, Tom G. van Oorschot, Viggo F. Van Tendeloo, Evelien L. Smits, Ghaith Bakdash, Gerty Schreibelt, I. Jolanda M. de Vries
Publikováno v:
Vaccines, Vol 6, Iss 3, p 65 (2018)
Dendritic cell (DC) vaccines show promising effects in cancer immunotherapy. However, their efficacy is affected by a number of factors, including (1) the quality of the DC vaccine and (2) tumor immune evasion. The recently characterized BDCA1+CD14+
Externí odkaz:
https://doaj.org/article/545800544f884054bd982ff4a699ebbb
Autor:
Arnaud Köhler, Roberta Mastrantonio, Ward Celus, Massimiliano Mazzone, Jens Serneels, Abhishek D. Garg, Sarah Trusso Cafarello, Luca Tamagnone, Jean-Christophe Marine, Oliver Bechter, Silvia Rivis, Ewout Landeloos, Yannick Van Herck, Ana Isabel Oliveira, Véronique Flamand, Mario Di Matteo, Heleen H. Van Acker, Bruno M. Costa
Publikováno v:
Cancer Immunol Res
Cytotoxic T cell (CTL) infiltration of the tumor carries the potential to limit cancer progression, but their exclusion by the immunosuppressive tumor microenvironment hampers the efficiency of immunotherapy. Here, we show that expression of the axon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701ba4fbeca6ed220bab98e7978d02eb
https://europepmc.org/articles/PMC7612191/
https://europepmc.org/articles/PMC7612191/
Publikováno v:
Trends Immunol
In the direct competition for metabolic resources between cancer cells and tumor-infiltrating CD8+ T cells, the latter are bound to lose out. These effector lymphocytes are therefore rendered exhausted or dysfunctional. Emerging insights into the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ab4b2983ba64ac1ba065022fe2919c
https://europepmc.org/articles/PMC9681987/
https://europepmc.org/articles/PMC9681987/
Autor:
Zoë P. Van Acker, Daniela Pende, Evelien Smits, Peter Ponsaerts, Zwi N. Berneman, Maarten Versteven, Sébastien Anguille, Viggo F I Van Tendeloo, Heleen H. Van Acker
Publikováno v:
Cancers, Vol 11, Iss 7, p 1029 (2019)
Cancers
Volume 11
Issue 7
Cancers
Volume 11
Issue 7
A particularly interesting marker to identify anti-tumor immune cells is the neural cell adhesion molecule (NCAM), also known as cluster of differentiation (CD)56. Namely, hematopoietic expression of CD56 seems to be confined to powerful effector imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffa39923844de2b409da9abf9558086
https://www.mdpi.com/2072-6694/11/7/1029
https://www.mdpi.com/2072-6694/11/7/1029