Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Heleen, VAN Melckebeke"'
Autor:
Heleen Van Melckebeke, Karen Leroy, Barbara Vanhoecke, Jean-Philippe Jais, Sofie Lust, Fabrice Jardin, Josette Brière, Jerina Boelens, Fritz Offner, Jan Philippé, Marc Bracke, Ilse M. Beck
Publikováno v:
Leukemia Research. 37:3-8
The process of B-cell development is characterized by the activation of the unfolded protein response. Under certain circumstances, the unfolded protein response can be manipulated in a cell death-inducing way. Therefore, tackling the unfolded protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581638465ea36e7d3ac09e77151ba852
https://doi.org/10.1016/j.leukres.2012.08.017
https://doi.org/10.1016/j.leukres.2012.08.017
Autor:
Michael R. Olson, Ioanna Papandreou, Fritz Offner, Donna M. Bouley, Heleen Van Melckebeke, Nicholas C. Denko, David E. Solow-Cordero, Arvin B. Tam, Maho Niwa, Albert C. Koong, Sofie Lust
Publikováno v:
Blood. 117(4)
Activation of the adaptive Ire1-XBP1 pathway has been identified in many solid tumors and hematologic malignancies, including multiple myeloma (MM). Here, we report the identification of STF-083010, a novel small-molecule inhibitor of Ire1. STF-08301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7a914869f7145922b3827edb425133
https://pubmed.ncbi.nlm.nih.gov/21081713
https://pubmed.ncbi.nlm.nih.gov/21081713
Autor:
Sofie, Lust, Barbara, Vanhoecke, Mireille, VAN Gele, Jerina, Boelens, Heleen, VAN Melckebeke, Mary, Kaileh, Wim, Vanden Berghe, Guy, Haegeman, Jan, Philippé, Marc, Bracke, Fritz, Offner
Publikováno v:
Anticancer Res
BACKGROUND: Chronic lymphocytic leukemia (CLL) is an incurable disease with a natural history of increasing resistance to chemotherapy. A novel approach to overcome chemotherapy resistance may be targeting the endoplasmic reticulum (ER). PATIENTS AND
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7042a9ce927ba688116acee0608cd7cd
https://pubmed.ncbi.nlm.nih.gov/19846911
https://pubmed.ncbi.nlm.nih.gov/19846911