Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Heleen, Kraan"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/464b3ea12dce47428c9705eff132762e
Mucosal immunity plays a pivotal role in protection against infection and the transmission of pathogens from person to person. Ideally, novel vaccines should be easy and safe to administer, provide mucosal immunity, be safe to manufacture, and be aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab0f14e75b48939c6b96093e3d8fa36
https://doi.org/10.1101/2022.07.28.501816
https://doi.org/10.1101/2022.07.28.501816
Autor:
Conor O'Mahony, Heleen Kraan, Olivia Flynn, Anne C. Moore, Peter C. Soema, Agnese Donadei, Olga Ophorst
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society.
The cessation of the oral poliovirus vaccine (OPV) and the inclusion of inactivated poliovirus (IPV) into all routine immunization programmes, strengthens the need for new IPV options. Several novel delivery technologies are being assessed that permi
Publikováno v:
Vaccine, 35(20), 2647-2653
Polio is on the brink of eradication. Improved inactivated polio vaccines (IPV) are needed towards complete eradication and for the use in the period thereafter. Vaccination via mucosal surfaces has important potential advantages over intramuscular i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2e5f6967c1e7ccfe9e376d1239f86f
http://hdl.handle.net/1887/57297
http://hdl.handle.net/1887/57297
Publikováno v:
Expert review of vaccines
Global polio eradication is closer than ever. Replacement of the live attenuated oral poliovirus vaccine (OPV) by inactivated poliovirus vaccine (IPV) is recommended to achieve complete eradication. Limited global production capacity and relatively h
Autor:
Bram Slütter, Vinay Saluja, Wim Jiskoot, Mohsen Tafaghodi, Jean-Pierre Amorij, Gideon F.A. Kersten, Heleen Kraan
Publikováno v:
Vaccine. 30:5341-5348
Mucosal immunization offers various advantages over parenteral vaccination, but typically requires potent delivery systems and/or adjuvants to result in protective immunity. Here we report on the preparation of trimethylated chitosan (TMC) and chitos
Autor:
Heleen Kraan, Gijsbert G.P. van de Wijdeven, Hoang Hirschberg, Jean-Pierre Amorij, Gideon F.A. Kersten
Publikováno v:
Journal of Controlled Release. 147:211-217
An alternative vaccine delivery system for needle injections is the Bioneedle. Hepatitis B surface antigen (HBsAg) was formulated with Bioneedles. Three formulations were used: plain antigen, HBsAg adjuvated with aluminum hydroxide and HBsAg with LPS
Autor:
Heleen Kraan, Jean-Pierre Amorij, Hilde Vrieling, Cecil Czerkinsky, Gideon F.A. Kersten, Wim Jiskoot
Publikováno v:
JOURNAL OF CONTROLLED RELEASE
Journal of Controlled Release
JOURNAL OF CONTROLLED RELEASE, 190, 580-592
Journal of Controlled Release
JOURNAL OF CONTROLLED RELEASE, 190, 580-592
Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination. An important characteristic of mucosal vaccination is its ability to elicit local immune responses, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c10ba0fa3d71ab731cd7d4d62c4e81
https://doi.org/10.1016/j.jconrel.2014.05.060
https://doi.org/10.1016/j.jconrel.2014.05.060
Autor:
Ivo Que, Gideon F.A. Kersten, Gijsbert G.P. van de Wijdeven, Ivo H J Ploemen, Heleen Kraan, Jean-Pierre Amorij, Clemens W.G.M. Löwik
Publikováno v:
Vaccine, 33(17), 2030-2037
In the near future oral polio vaccine (OPV) will be replaced by inactivated polio vaccine (IPV) as part of the eradication program of polio. For that reason, there is a need for substantial amount of safe and more affordable IPV for low-income countr
Autor:
Ivo H J, Ploemen, Hoang J H B, Hirschberg, Heleen, Kraan, Adrian, Zeltner, Sandra, van Kuijk, Danielle P K, Lankveld, Michael, Royals, Gideon F A, Kersten, Jean-Pierre, Amorij
Publikováno v:
Comparative medicine. 64(1)
Appropriate animal models for intradermal vaccine delivery are scarce. Given the high similarity of their skin anatomy to that of humans, minipigs may be a suitable model for dermal vaccine delivery. Here we describe the immunization of Göttingen mi