Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia

Autor: Heikki Kuusanmäki, Aino-Maija Leppä, Petri Pölönen, Mika Kontro, Olli Dufva, Debashish Deb, Bhagwan Yadav, Oscar Brück, Ashwini Kumar, Hele Everaus, Bjørn T. Gjertsen, Merja Heinäniemi, Kimmo Porkka, Satu Mustjoki, Caroline A. Heckman

Publikováno v: Haematologica, Vol 105, Iss 3 (2020)

Externí odkaz: https://doaj.org/article/9d9ce60433f4483e96edb2bc4fcd137d

Safety and efficacy of durvalumab with R-CHOP or R2-CHOP in untreated, high-risk DLBCL:a phase 2, open-label trial

Autor: Wolfgang Willenbacher, Brian Fox, Peter de Nully Brown, Judit Jørgensen, Neus Domper Rubio, Marie-Laure Casadebaig, Richard Greil, Hele Everaus, Ulrich Jäger, Lorenz Trümper, David Cunningham, Oliver Manzke, Thomas Stauffer Larsen, Krish Patel, Justine Dell’Aringa, Nurgul Kilavuz, Grzegorz S. Nowakowski, Nagesh Kalakonda, Robert Manges, Javier Munoz

Publikováno v: Nowakowski, G S, Willenbacher, W, Greil, R, Larsen, T S, Patel, K, Jäger, U, Manges, R F, Trümper, L, Everaus, H, Kalakonda, N, Brown, P, Jørgensen, J M, Cunningham, D, Dell’Aringa, J, Fox, B, Rubio, N D, Kilavuz, N, Casadebaig, M L, Manzke, O & Munoz, J 2022, ' Safety and efficacy of durvalumab with R-CHOP or R 2-CHOP in untreated, high-risk DLBCL : a phase 2, open-label trial ', International Journal of Hematology, vol. 115, no. 2, pp. 222-232 . https://doi.org/10.1007/s12185-021-03241-4
Nowakowski, G S, Willenbacher, W, Greil, R, Larsen, T S, Patel, K, Jäger, U, Manges, R F, Trümper, L, Everaus, H, Kalakonda, N, Brown, P, Jørgensen, J M, Cunningham, D, Dell'Aringa, J, Fox, B, Rubio, N D, Kilavuz, N, Casadebaig, M-L, Manzke, O & Munoz, J 2022, ' Safety and efficacy of durvalumab with R-CHOP or R 2-CHOP in untreated, high-risk DLBCL : a phase 2, open-label trial ', International Journal of Hematology, vol. 115, no. 2, pp. 222-232 . https://doi.org/10.1007/s12185-021-03241-4

Patients with high-risk diffuse large B-cell lymphoma (DLBCL) have poor outcomes following first-line cyclophosphamide, doxorubicin, vincristine, prednisone, and rituximab (R-CHOP). Evidence shows chemotherapy and immune checkpoint blockade can incre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d8c12cf157023fa610230261b321fc
https://portal.findresearcher.sdu.dk/da/publications/a1eda3b7-edc6-42d6-9940-c2ac96b43009

The EUTOS long-term survival (ELTS) score is superior to the Sokal score for predicting survival in chronic myeloid leukemia

Autor: Andrija Bogdanovic, Boris Labar, Martin Höglund, Edgar Faber, Hele Everaus, Richard E. Clark, Adriana Colita, Rüdiger Hehlmann, Sonja Heibl, Anna G. Turkina, Ulla Olsson-Strömberg, Francisco Cervantes, Michele Baccarani, Tomasz Sacha, Verena S. Hoffmann, Michael Lauseker, Daniela Zackova, Markus Pfirrmann, Andreas Hochhaus, Laimonas Griskevicius, Perttu Koskenvesa, Susanne Saussele, Irena Preložnik Zupan, Joerg Hasford, Andrey Zaritskey, Gert J. Ossenkoppele, Fausto Castagnetti, Witold Prejzner, François Guilhot, Joelle Guilhot

Publikováno v: Leukemia
Leukemia, 34(8), 2138-2149. Nature Publishing Group
Leukemia, London : Nature Publishing Group, 2020, vol. 34, no. 8, p. 2138-2149
Pfirrmann, M, Clark, R E, Prejzner, W, Lauseker, M, Baccarani, M, Saussele, S, Guilhot, F, Heibl, S, Hehlmann, R, Faber, E, Turkina, A, Ossenkoppele, G, Höglund, M, Zaritskey, A, Griskevicius, L, Olsson-Strömberg, U, Everaus, H, Koskenvesa, P, Labar, B, Sacha, T, Zackova, D, Cervantes, F, Colita, A, Zupan, I, Bogdanovic, A, Castagnetti, F, Guilhot, J, Hasford, J, Hochhaus, A & Hoffmann, V S 2020, ' The EUTOS long-term survival (ELTS) score is superior to the Sokal score for predicting survival in chronic myeloid leukemia ', Leukemia, vol. 34, no. 8, pp. 2138-2149 . https://doi.org/10.1038/s41375-020-0931-9

Prognostic scores support clinicians in selecting risk-adjusted treatments and in comparatively assessing different results. For patients with chronic-phase chronic myeloid leukemia (CML), four baseline prognostic scores are commonly used. Our aim wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844e55b4db4ff681f41581c3ef23a513
https://pubmed.ncbi.nlm.nih.gov/32601376

Polymorphisms in COMT and SULT1A1 Genes and Chronic Lymphocytic Leukemia Risk in Estonia

Autor: Kristi Kasemaa, Hele Everaus, Katrin Sak

Publikováno v: Eurasian Journal of Medicine and Oncology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f64a6a9dff45805b92e774449a1d7a14
https://doi.org/10.14744/ejmo.2019.51146

Potentiation of luteolin cytotoxicity by flavonols fisetin and quercetin in human chronic lymphocytic leukemia cell lines

Autor: Kristi Kasemaa, Hele Everaus, Katrin Sak

Publikováno v: Food & Function. 7:3815-3824

Despite numerous studies chronic lymphocytic leukemia (CLL) still remains an incurable disease. Therefore, all new compounds and novel strategies which are able to eradicate CLL cells should be considered as valuable clues for a potential future reme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918603d4780cf58264ea74d5c3817d9f
https://doi.org/10.1039/c6fo00583g