Zobrazeno 1 - 10
of 1 283
pro vyhledávání: '"Heldin P"'
Autor:
Eleftheria Vasilaki, Yu Bai, Mohamad Moustafa Ali, Anders Sundqvist, Aristidis Moustakas, Carl-Henrik Heldin
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background p63 is a transcription factor with intrinsic pioneer factor activity and pleiotropic functions. Transforming growth factor β (TGFβ) signaling via activation and cooperative action of canonical, SMAD, and non-canonical, MAP-kinas
Externí odkaz:
https://doaj.org/article/c69b2398770746ad995d89ef0e1932d9
Publikováno v:
Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101828- (2024)
This study investigates the role of Rho GTPases, specifically Cdc42, Rac1, and RhoA, in platelet-derived growth factor receptors (PDGFRα and PDGFRβ) signaling. Signal transducer and activator of transcription (STAT) proteins, essential for cellular
Externí odkaz:
https://doaj.org/article/0ead78c0dd9f4c8dab4a3183a22ef1f2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Angelos Heldin, Matko Cancer, Mireia Palomar-Siles, Susanne Öhlin, Meiqiongzi Zhang, Alexander Sun-Zhang, Anna Mariani, Jianping Liu, Vladimir J.N. Bykov, Klas G. Wiman
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 368-383 (2023)
The TP53 and PTEN tumour suppressor genes are inactivated by nonsense mutations in a significant fraction of human tumours. TP53 nonsense mutant tumours account for approximately one million new cancer cases per year worldwide. We have screened chemi
Externí odkaz:
https://doaj.org/article/daccee69e3db47eebcd34fa7604e554b
Autor:
Caroline Gélabert, Panagiotis Papoutsoglou, Irene Golán, Eric Ahlström, Adam Ameur, Carl-Henrik Heldin, Laia Caja, Aristidis Moustakas
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-26 (2023)
Abstract Background Long non-coding RNAs (lncRNAs) regulate cellular processes by interacting with RNAs or proteins. Transforming growth factor β (TGFβ) signaling via Smad proteins regulates gene networks that control diverse biological processes,
Externí odkaz:
https://doaj.org/article/a582c71957894d6caef289ea2cc1fa2b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
BMC Molecular and Cell Biology, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background The platelet-derived growth factor (PDGF) family of ligands exerts their cellular effects by binding to α- and β-tyrosine kinase receptors (PDGFRα and PDGFRβ, respectively). SUMOylation is an important posttranslational modifi
Externí odkaz:
https://doaj.org/article/1ae0a1c24b224b0582c6b96dc03428a2
Autor:
Mireia Palomar-Siles, Angelos Heldin, Meiqiongzi Zhang, Charlotte Strandgren, Viktor Yurevych, Jip T. van Dinter, Sem A. G. Engels, Damon A. Hofman, Susanne Öhlin, Birthe Meineke, Vladimir J. N. Bykov, Sebastiaan van Heesch, Klas G. Wiman
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-17 (2022)
Abstract TP53 nonsense mutations in cancer produce truncated inactive p53 protein. We show that 5-FU metabolite 5-Fluorouridine (FUr) induces full-length p53 in human tumor cells carrying R213X nonsense mutant TP53. Ribosome profiling visualized tran
Externí odkaz:
https://doaj.org/article/d20df1692ffe43d69b4b2923e7b6b3b8
Autor:
Joseph J. Tonge, Scott V. Notley, Mark J. Dunning, Ana López-Guajardo, Jessica D. Medcalf, Paraskevi Heldin, George Panoutsos, Annica K. B. Gad
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Infantile fibrosarcoma is a rare childhood tumour that originates in the fibrous connective tissue of the long bones for which there is an urgent need to identify novel therapeutic targets. This study aims to clarify the role of the extracel
Externí odkaz:
https://doaj.org/article/73e613197a564c4189d7259d2152523b
Autor:
Heldin J, Malinovschi A, Johannessen A, Alving K, Holm M, Franklin KA, Forsberg B, Schlünssen V, Jögi R, Gislason T, Benediktsdottir B, Svanes C, Janson C
Publikováno v:
Journal of Asthma and Allergy, Vol Volume 15, Pp 1569-1578 (2022)
Johanna Heldin,1 Andrei Malinovschi,2 Ane Johannessen,3 Kjell Alving,4 Mathias Holm,5 Karl A Franklin,6 Bertil Forsberg,7 Vivi Schlünssen,8,9 Rain Jögi,10 Thorarinn Gislason,11,12 Bryndis Benediktsdottir,11,12 Cecilie Svanes,3,13 Christer Janson1 1
Externí odkaz:
https://doaj.org/article/38a2ddecf36a460f847dae89ebab58f9