Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Helder I, Nakaya"'
Autor:
Alysson Henrique Urbanski, Vanessa E. Maso, Felipe M. Martins, André Guilherme da Costa-Martins, Ana Paula B. do Nascimento Oliveira, Helder I. Nakaya
Publikováno v:
Infectious Disease Reports, Vol 16, Iss 5, Pp 914-922 (2024)
Chikungunya fever (CHIKF), caused by the Chikungunya virus (CHIKV), manifests as acute febrile illness often associated with polyarthritis and polyarthralgia. Although the acute symptoms resolve within two weeks, many patients experience prolonged jo
Externí odkaz:
https://doaj.org/article/35a1289a78f8464ebc72997c077298df
Autor:
Cíntia J. Monteiro, Max J. Duarte, Mayara Cristina V. Machado, Romário S. Mascarenhas, Patrícia V. Bonini Palma, Henry D. Mogollón García, Helder I. Nakaya, Thiago M. Cunha, Eduardo A. Donadi, Geraldo A. Passos
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
To further understand the impact of deficiency of the autoimmune regulator (Aire) gene during the adhesion of medullary thymic epithelial cells (mTECs) to thymocytes, we sequenced single-cell libraries (scRNA-seq) obtained from Aire wild-type (WT) (A
Externí odkaz:
https://doaj.org/article/a84e56953c1d4fe7bf9dbf09a52ed2ce
Autor:
Tiago Lubiana, Helder I. Nakaya
Publikováno v:
The Lancet Regional Health. Americas, Vol 35, Iss , Pp 100795- (2024)
Externí odkaz:
https://doaj.org/article/cca2e50558234b97bd8a7e1fd311c296
Autor:
Tiffany B. L. Costa-Gouvea, Katia S. Françoso, Rodolfo F. Marques, Alba Marina Gimenez, Ana C. M. Faria, Leonardo M. Cariste, Mariana R. Dominguez, José Ronnie C. Vasconcelos, Helder I. Nakaya, Eduardo L. V. Silveira, Irene S. Soares
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Malaria remains a global health challenge, necessitating the development of effective vaccines. The RTS,S vaccination prevents Plasmodium falciparum (Pf) malaria but is ineffective against Plasmodium vivax (Pv) disease. Herein, we evaluated the murin
Externí odkaz:
https://doaj.org/article/3a2085bd9a8649d9b5558600265539c9
Autor:
Felipe de Mello Martins, Alessandra Pinheiro Vidal, Jeevan Giddaluru, Bernardo Maia da Silva, Eva K. Lee, Peijue Zhang, Lucas Esteves Cardozo, Carlos Augusto Prete Junior, Helves Humberto Domingues, Ester Cerdeira Sabino, Vanderson de Souza Sampaio, Wuelton Marcelo Monteiro, Helder I Nakaya
Publikováno v:
Einstein (São Paulo), Vol 22 (2024)
ABSTRACT Objective: This study aimed to present a temporal and spatial analysis of the 2018 measles outbreak in Brazil, particularly in the metropolitan city of Manaus in the Amazon region, and further introduce a new tool for spatial analysis. Metho
Externí odkaz:
https://doaj.org/article/d513efcc39e64b72a4ba3816adf36a99
Autor:
Eleonora Vianello, Josefine Persson, Björn Andersson, Suzanne van Veen, Thomaz Lüscher Dias, Francesco Santoro, Malin Östensson, Ogonna Obudulu, Christopher Agbajogu, Sara Torkzadeh, Helder I. Nakaya, Donata Medaglini, Claire-Anne Siegrist, Tom H.M. Ottenhoff, Ali M. Harandi, Selidji Todagbe Agnandji, Rafi Ahmed, Jenna Anderson, Floriane Auderset, Philip Bejon, Luisa Borgianni, Jessica Brosnahan, Annalisa Ciabattini, Olivier Engler, Marielle C. Haks, Donald Gray Heppner, Alice Gerlini, Angela Huttner, Peter G. Kremsner, Thomas Monath, Francis Ndungu, Patricia Njuguna, David Pejoski, Mark Page, Gianni Pozzi, Sheri Dubey, Micheal J. Eichberg, Patrícia Gonzalez-Dias, Paulin Ndong Essone, Lumeka Kabwende, Peter Gottfried Kremsner, Helder Nakaya, Sravya S. Nakka, Mariëlle C. Haks, Sylvia Rothenberger
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108574- (2023)
Summary: The vectored Ebola vaccine rVSVΔG-ZEBOV-GP elicits protection against Ebola Virus Disease (EVD). In a study of forty-eight healthy adult volunteers who received either the rVSVΔG-ZEBOV-GP vaccine or placebo, we profiled intracellular micro
Externí odkaz:
https://doaj.org/article/d1e7ad08e3484b79982a9a85a16c47ce
Autor:
Patrícia Conceição Gonzalez Dias Carvalho, Thiago Dominguez Crespo Hirata, Leandro Yukio Mano Alves, Isabelle Franco Moscardini, Ana Paula Barbosa do Nascimento, André G. Costa-Martins, Sara Sorgi, Ali M. Harandi, Daniela M. Ferreira, Eleonora Vianello, Mariëlle C. Haks, Tom H. M. Ottenhoff, Francesco Santoro, Paola Martinez-Murillo, Angela Huttner, Claire-Anne Siegrist, Donata Medaglini, Helder I. Nakaya
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe rVSVDG-ZEBOV-GP (Ervebo®) vaccine is both immunogenic and protective against Ebola. However, the vaccine can cause a broad range of transient adverse reactions, from headache to arthritis. Identifying baseline reactogenicity signatur
Externí odkaz:
https://doaj.org/article/9b246c2c294f43e584d1ad881d52ea58
Autor:
Mariana Severo Ramundo, Guilherme Cordenonsi da Fonseca, Alexandra L. Gerber, Ana Paula Guimarães, Erika Regina Manuli, Marina Farrel Côrtes, Geovana Maria Pereira, Otavio Brustolini, Patrícia Brasil, Helder I. Nakaya, Gláucia Paranhos-Baccalà, Ana Tereza R. Vasconcelos, Ester Cerdeira Sabino
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 27, Iss , Pp 103431- (2023)
Introdução/Objetivo: Infecções pelo vírus Chikungunya (CHIKV) podem frequentemente resultar no desenvolvimento de Doença Articular Inflamatória Crônica pós-Chikungunya (pCHIKV-CIJD). Essa condição gera impactos na qualidade de vida dos pac
Externí odkaz:
https://doaj.org/article/a30f84371eb845cabeb40fd64849c656
Autor:
Érika Pereira Zambalde, Thomaz Luscher Dias, Grazielle Celeste Maktura, Mariene R. Amorim, Bianca Brenha, Luana Nunes Santos, Lucas Buscaratti, João Gabriel de Angeli Elston, Mariana Camargo Silva Mancini, Isadora Carolina Betim Pavan, Daniel A. Toledo-Teixeira, Karina Bispo-dos-Santos, Pierina L. Parise, Ana Paula Morelli, Luiz Guilherme Salvino da Silva, Ícaro Maia Santos de Castro, Tatiana D. Saccon, Marcelo A. Mori, Fabiana Granja, Helder I. Nakaya, Jose Luiz Proenca-Modena, Henrique Marques-Souza, Fernando Moreira Simabuco
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 1, Pp 327-336 (2022)
The COVID-19 (Coronavirus Disease 2019), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), severely affects mainly individuals with pre-existing comorbidities. Here our aim was to correlate the mTOR (mammalian/mechanistic Ta
Externí odkaz:
https://doaj.org/article/100e2fe393e1485f9350e2393da3bc1e
Autor:
Tiago Lubiana, Rafael Lopes, Pedro Medeiros, Juan Carlo Silva, Andre Nicolau Aquime Goncalves, Vinicius Maracaja-Coutinho, Helder I Nakaya
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011319 (2023)
Externí odkaz:
https://doaj.org/article/7cbcd1a38090412a8b67b54ae50293b1