Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Helawe Betre"'
Autor:
Michael R. Zalutsky, Wenge Liu, Ashutosh Chilkoti, Virginia B. Kraus, Helawe Betre, Lori A. Setton
Publikováno v:
Journal of Controlled Release. 115:175-182
Intra-articular drug delivery is the preferred standard for targeting pharmacologic treatment directly to joints to reduce undesirable side effects associated with systemic drug delivery. In this study, a biologically based drug delivery vehicle was
Autor:
Mohammed F. Shamji, Ashutosh Chilkoti, Virginia B. Kraus, Helawe Betre, Rajeswari Pichika, Jun Chen, Lori A. Setton, Koichi Masuda
Publikováno v:
Arthritis and rheumatism. 56(11)
Objective Interleukin-1 receptor antagonist (IL-1Ra) has been evaluated for the intraarticular treatment of osteoarthritis. Such administration of proteins may have limited utility because of their rapid clearance and short half-life in the joint. Th
Autor:
Shin R. Ong, Ashutosh Chilkoti, Farshid Guilak, Helawe Betre, Beverley Fermor, Lori A. Setton
Publikováno v:
Biomaterials. 27(1)
Human adipose derived adult stem (hADAS) cells have the ability to differentiate into a chondrogenic phenotype in three-dimensional culture and media containing dexamethasone and TGF-β. The current study examined the potential of a genetically engin
Publikováno v:
Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology.
A "two step" tissue engineering strategy was developed to promote rapid matrix accumulation in cartilage constructs in vitro. Chondrocytes expanded in monolayer were encapsulated and cultured in a genetically engineered, thermally sensitive elastin-l
Publikováno v:
Biomacromolecules. 3(5)
Elastin-like polypeptides (ELPs) are artificial polypeptides with unique properties that make them attractive as a biomaterial for tissue-engineered cartilage repair. ELPs are composed of a pentapeptide repeat, Val-Pro-Gly-Xaa-Gly (Xaa is any amino a
Autor:
Mohammed F. Shamji, Jun Chen, Ashutosh Chilkoti, Lori A. Setton, Virginia B. Kraus, Helawe Betre
Publikováno v:
Osteoarthritis and Cartilage. :C226-C227