Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hekmat M El Magdoub"'
Autor:
Hala O El-Mesallamy, Hekmat M El Magdoub, James M Chapman, Nadia M Hamdy, Mona F Schaalan, Lamiaa N Hammad, Sondra H Berger
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193810 (2018)
Thymidylate synthase (TS) is a well-validated target for the therapy of adult cancers. Propane-1,3-diphosphonic acid (PDPA) has significant inhibitory properties against human thymidylate synthase (hTS) relative to mouse TS which is not predicted to
Externí odkaz:
https://doaj.org/article/c969d40cc3eb4e17b48edb20133d05c3
Autor:
Rana A. Youness, Hossam A. Hassan, Tasneem Abaza, Ahmed A. Hady, Hekmat M. El Magdoub, Mohamed Ali, Johannes Vogel, Markus Thiersch, Max Gassmann, Nadia M. Hamdy, Mostafa A. Aboouf
Publikováno v:
Cells, Vol 13, Iss 15, p 1245 (2024)
Circular RNAs (circRNAs) are cardinal players in numerous physiological and pathological processes. CircRNAs play dual roles as tumor suppressors and oncogenes in different oncological contexts, including hepatocellular carcinoma (HCC). Their roles s
Externí odkaz:
https://doaj.org/article/bf9cdc23f9074828a9909ce4da9bda2d
Autor:
Entsar R. Mokhtar, Asmaa A. Elmadbouly, Omaima I. Abo Elkheir, Mona Nabeh Mansour, Shahinaz El Attar, Mohamed A. Heiba, Mennatullah N. Mohamed, Heba Elhakeem, Lamia A. Gad, Heba Mahmoud Abdelrahman, Rehab Moustafa Kamel, Hekmat M. El Magdoub, Nadia M. Hamdy, Doaa Aly Abd El-Fattah
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 485 (2024)
Although primary open-angle glaucoma (POAG) is a major cause of blindness worldwide, patients’ immune response and its relation to the disease course have not been fully unraveled in terms of analyses of circulating B-cell subsets, as well as the a
Externí odkaz:
https://doaj.org/article/8823f8bc625d4e67b58ad92efd6c9973
Autor:
Ahmed M Mohamed, Mohamed Z. Habib, Sawsan Aboul-Fotouh, Mai A. Ebeid, Yasser el Faramawy, Omnyah A. El-Kharashi, Sherin S.T. Saad, Hekmat M. El Magdoub, Ahmed M. Abdel-tawab, Hadwa A. Abd-Alkhalek
Publikováno v:
Neurotoxicology. 83
Low-dose repeated lipopolysaccharide pre-challenge followed by chronic mild stress (LPS/CMS) protocol has been introduced as a rodent model of depression combining the roles of immune activation and chronic psychological stress. However, the impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330942eec8071f5b01c8ff797e8aa2fe
https://pubmed.ncbi.nlm.nih.gov/33417987
https://pubmed.ncbi.nlm.nih.gov/33417987
Autor:
Hekmat M. El Magdoub, Mohamed Hafez Shaaban, Hoda H Abou Gabal, Nashwa El-Khazragy, Sherief Ghozy, Ahmed Bayoumi, Azzah M. Bannunah, Amal A. Elshimy, Marwa M. Aboelhussein, Ahmed Gaballah, Azza El‐Sayed Mansy, Safaa S. Hassan
Publikováno v:
Molecular carcinogenesisREFERENCES. 59(12)
Emerging hepatocellular carcinoma (HCC) has been sequentially reported in chronic hepatitis C virus (HCV) treated with direct-acting antivirals (DAAs). Homeobox transcript antisense RNA (HOTAIR), an oncogene, has been reported to be associated with c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7712805e6de7bbe82f3c3353bd987e79
https://pubmed.ncbi.nlm.nih.gov/33074585
https://pubmed.ncbi.nlm.nih.gov/33074585
Emerging role of miRNAs as liquid biopsy markers for prediction of glioblastoma multiforme prognosis
Publikováno v:
Journal of molecular neuroscience : MN. 71(4)
Serum miRNAs (miRs) have gained consideration as encouraging molecular markers for cancer diagnosis and prediction of prognosis. The authors aimed to identify the exact role of miR-17-5p, miR-125b, and miR-221 among glioblastoma multiforme (GBM) pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fff5ea32f54586e6e827277ef976437
https://pubmed.ncbi.nlm.nih.gov/32989634
https://pubmed.ncbi.nlm.nih.gov/32989634
Autor:
Hayam F Mohammed, Khouloud Zedan, Mohamed Yassin, Nashwa El-Khazragy, Azzah M. Bannunah, Azza El‐Sayed Mansy, Salema Salem, K.K. Elghoneimy, Gehan Safwat, Wael M. Elayat, Amr Attia Hewety, Mai Mosa, W S Zaki, Hekmat M. El Magdoub, Walid Abd Elmoniem Bayoumy
Publikováno v:
Genomics. 112(6)
Objectives The current study aimed to investigate the potentiality of three lncRNAs “Plasmacytoma variant translocation 1(lnc-PVT1), Taurine upregulated gene type 1(lnc-TUG1) and Maternally expressed gene 3 (lnc-MEG-3)”, to predict Cisplatin resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab1be6bdf41b75d2d2ff8ed97b4d477
https://pubmed.ncbi.nlm.nih.gov/32781203
https://pubmed.ncbi.nlm.nih.gov/32781203
Autor:
Marwa Adel, Menha Swellam, May A. Shawki, Samar Sami El-Shazly, Hekmat M. El Magdoub, Mona M. Hefny
Publikováno v:
Current Problems in Cancer. 45:100709
Long noncoding RNAs (lncRNAs) are evolving as contributing biomarkers for many diseases. Among these lncRNAs, X inactive-specific transcript (XIST), and nuclear paraspeckle assembly transcript 1 (NEAT1) were studied as undesirable upregulated nucleic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843abbc29aad94c2cddf7d53df3f784f
https://doi.org/10.1016/j.currproblcancer.2021.100709
https://doi.org/10.1016/j.currproblcancer.2021.100709
Autor:
Ghada A. Abdel-Latif, Hekmat M. El Magdoub, Mona F. Schaalan, Samah S. Abbas, Rania M. Salama
Publikováno v:
Neuropharmacology. 164
The complexity of Parkinson's disease (PD) pathogenesis is attributed to multiple pathways involved in the neurodegeneration process. Among these pathways arise the phosphoinositide 3–kinase (PI3K)/protein kinase B (Akt), and mammalian target of ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3a2053edd302ae5e046d14942b412b
https://pubmed.ncbi.nlm.nih.gov/31811872
https://pubmed.ncbi.nlm.nih.gov/31811872