Combining nilotinib and PD-L1 blockade reverses CD4+ T-cell dysfunction and prevents relapse in acute B-cell leukemia.

Autor: Tracy SI; Center for Immunology.; Masonic Cancer Center.; Division of Hematology, Oncology and Transplantation, Department of Medicine, and., Venkatesh H; Center for Immunology.; Masonic Cancer Center.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN., Hekim C; Center for Immunology.; Masonic Cancer Center.; Orion Corporation, R&D, Immuno-Oncology Unit Tengströminkatu, Turku, Finland; and., Heltemes-Harris LM; Center for Immunology.; Masonic Cancer Center.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN., Knutson TP; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN., Bachanova V; Masonic Cancer Center.; Division of Hematology, Oncology and Transplantation, Department of Medicine, and., Farrar MA; Center for Immunology.; Masonic Cancer Center.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.

Publikováno v: Blood [Blood] 2022 Jul 28; Vol. 140 (4), pp. 335-348.

Thymic regulatory T cells arise via two distinct developmental programs.

Autor: Owen DL; Center for Immunology, Masonic Cancer Center, and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Mahmud SA; Center for Immunology, Masonic Cancer Center, and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Sjaastad LE; Center for Immunology, Masonic Cancer Center, and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Williams JB; Section of Rheumatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Spanier JA; Center for Immunology, Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Simeonov DR; Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA.; Diabetes Center, University of California San Francisco, San Francisco, CA, USA.; Biomedical Sciences Graduate Program, University of California San Francisco, San Francisco, CA, USA., Ruscher R; Center for Immunology, Masonic Cancer Center, and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Huang W; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.; Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA., Proekt I; Diabetes Center, University of California San Francisco, San Francisco, CA, USA., Miller CN; Diabetes Center, University of California San Francisco, San Francisco, CA, USA., Hekim C; Center for Immunology, Masonic Cancer Center, and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Jeschke JC; Section of Rheumatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Aggarwal P; Section of Genomic Pediatrics, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Broeckel U; Section of Genomic Pediatrics, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., LaRue RS; Supercomputing Institute for Advanced Computational Research, University of Minnesota, Minneapolis, MN, USA., Henzler CM; Supercomputing Institute for Advanced Computational Research, University of Minnesota, Minneapolis, MN, USA., Alegre ML; Section of Rheumatology, Department of Medicine, University of Chicago, Chicago, IL, USA., Anderson MS; Diabetes Center, University of California San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., August A; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA., Marson A; Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA.; Diabetes Center, University of California San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, CA, USA., Zheng Y; Nomis Foundation Laboratories for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, CA, USA., Williams CB; Section of Rheumatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Farrar MA; Center for Immunology, Masonic Cancer Center, and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA. farra005@umn.edu.

Publikováno v: Nature immunology [Nat Immunol] 2019 Feb; Vol. 20 (2), pp. 195-205. Date of Electronic Publication: 2019 Jan 14.

Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models.

Autor: Hekim C; Hematology Research Unit Helsinki, Department of Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland., Ilander M; Hematology Research Unit Helsinki, Department of Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland., Yan J; Bristol-Myers Squibb Research and Development, Princeton, New Jersey., Michaud E; Bristol-Myers Squibb Research and Development, Princeton, New Jersey., Smykla R; Bristol-Myers Squibb Research and Development, Princeton, New Jersey., Vähä-Koskela M; Cancer Gene Therapy Group, Department of Pathology and Transplantation Laboratory, Haartman Institute, University of Helsinki, Finland., Savola P; Hematology Research Unit Helsinki, Department of Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland., Tähtinen S; Cancer Gene Therapy Group, Department of Pathology and Transplantation Laboratory, Haartman Institute, University of Helsinki, Finland., Saikko L; Department of Pathology, HUSLAB and Haartman Institute, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland., Hemminki A; Cancer Gene Therapy Group, Department of Pathology and Transplantation Laboratory, Haartman Institute, University of Helsinki, Finland., Kovanen PE; Department of Pathology, HUSLAB and Haartman Institute, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland., Porkka K; Hematology Research Unit Helsinki, Department of Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland., Lee FY; Bristol-Myers Squibb Research and Development, Princeton, New Jersey., Mustjoki S; Hematology Research Unit Helsinki, Department of Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland. satu.mustjoki@helsinki.fi.; Department of Clinical Chemistry, University of Helsinki, Helsinki, Finland.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2017 Feb; Vol. 5 (2), pp. 157-169. Date of Electronic Publication: 2017 Jan 10.

AARS2 as a novel biomarker for prognosis and its molecular characterization in pan‐cancer.

Autor: Liu, Long^1,2,3 (AUTHOR), Gao, Jie^1,2,3 (AUTHOR), Liu, Xudong^1,2,3 (AUTHOR), Zhang, Feng^1,2,3 (AUTHOR), Hu, Bowen^1,4,5,6 (AUTHOR), Zhang, Huapeng^1,4,5,6 (AUTHOR), Wang, Zhihui^1,4,5,6 (AUTHOR), Tang, Hongwei^1,2,3 (AUTHOR), Shi, Ji Hua^1,2,3,4,5,6 (AUTHOR), Zhang, Shuijun^1,2,3,4,5,6 (AUTHOR) zhangshuijun@zzu.edu.cn

Publikováno v: Cancer Medicine. Dec2023, Vol. 12 Issue 23, p21531-21544. 14p.

An Open Letter in Support of Transformative Biotechnology and Social Innovation: SANKO University Innovation Summit in Medicine and Integrative Biology, Gaziantep, Turkey, May 5-7, 2016.

Autor: Saygılı Eİ; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Abou-Zeid AH; 2 Faculty of Medicine, Cairo University , Cairo, Egypt ., Akkın SM; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Aklillu E; 3 Department of Physiology and Pharmacology, Karolinska Institutet , Solna, Sweden ., Barlas İÖ; 4 Faculty of Medicine, Department of Medical Biology and Genetics, Mersin University , Mersin, Turkey ., Borda-Rodriguez A; 5 Development Policy and Practice Group, The Open University , Milton Keynes, United Kingdom .; 6 Secretaria Nacional de Educacion Superior , Ciencia, Tecnologia e Innovacion, Quito, Ecuador ., Boschele FA; 7 Faculty of Communications, Marmara University , Istanbul, Turkey ., Çetin Z; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Coşkun E; 8 Faculty of Life Sciences & Medicine, King's College London , London, United Kingdom .; 9 Faculty of Medicine, Faculty of Engineering, Gaziantep University , Gaziantep, Turkey ., Coşkun Y; 9 Faculty of Medicine, Faculty of Engineering, Gaziantep University , Gaziantep, Turkey .; 10 Office of the President, Faculty of Engineering, Gaziantep University , Gaziantep, Turkey ., Dağlı G; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Dai TU; 7 Faculty of Communications, Marmara University , Istanbul, Turkey ., Dandara C; 11 Division of Human Genetics, Department of Pathology & Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town , South Africa ., Dereli T; 12 Office of the President and Technology Transfer Office, İskenderun Technical University (İSTE) , İskenderun, Turkey .; 13 Department of Industrial Engineering, Faculty of Engineering, Gaziantep University , Gaziantep, Turkey ., Elbeyli L; 9 Faculty of Medicine, Faculty of Engineering, Gaziantep University , Gaziantep, Turkey ., Endrenyi L; 14 Faculty of Medicine, University of Toronto , Toronto, Ontario, Canada ., Eyigün CP; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Georgakilas A; 15 Department of Physics, National Technical University of Athens , Athens, Greece ., Günbulut B; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Güngör K; 9 Faculty of Medicine, Faculty of Engineering, Gaziantep University , Gaziantep, Turkey ., Güzelbey A; 16 Independent Scholars, Gaziantep, Turkey ., Hekim C; 17 Independent Scholars, Uppsala, Sweden ., Huzair F; 18 School of Social and Political Sciences, The University of Edinburgh , Edinburgh, United Kingdom ., Kimyon S; 9 Faculty of Medicine, Faculty of Engineering, Gaziantep University , Gaziantep, Turkey ., Karakaş Ü; 4 Faculty of Medicine, Department of Medical Biology and Genetics, Mersin University , Mersin, Turkey ., Lin B; 19 University of Washington , Seattle, Washington, USA.; 20 Systems Biology Division, Zhejiang-California International Nanosystems Institute (ZCNI) of Zhejiang University , Hangzhou, China ., LLerena A; 21 Clinical Research Center, Extremadura University Hospital and Medical School , Hospital Infanta Cristina Av de Elvas s/n, Badajoz, Spain ., Masimirembwa C; 22 African Institute of Biomedical Science & Technology , Harare, Zimbabwe ., McNally R; 23 Anglia Ruskin University , Cambridge, United Kingdom ., Mete A; 9 Faculty of Medicine, Faculty of Engineering, Gaziantep University , Gaziantep, Turkey ., Sancar P; 24 Independent Scholars, Istanbul, Turkey ., Srivastava S; 25 Proteomics Laboratory, Indian Institute of Technology Bombay , Powai, Mumbai, India ., Steuten LM; 26 PANAXEA bv, University of Twente , Enschede, The Netherlands .; 27 Fred Hutchinson Cancer Research Center, Hutchinson Institute for Cancer Outcomes Research and School of Pharmacy, Pharmaceutical Outcomes Research and Policy Program, University of Washington , Seattle, Washington, USA., Tanrıöver O; 7 Faculty of Communications, Marmara University , Istanbul, Turkey ., Tyfield D; 28 Centre for Mobilities Research (CeMoRe), Lancaster University , Lancaster, United Kingdom .; 29 International Research & Innovation Centre for the Environment (I-RICE) , Guangzhou, China ., Töre Vİ; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Vuruşkan D; 30 Gaziantep University Technopark and the Department of Textile Engineering , Faculty of Engineering, Gaziantep University , Gaziantep, Turkey ., Wang W; 31 Global Health Genomics, School of Medical Sciences and Health, Edith Cowan University , Perth, Australia .; 32 Beijing Municipal Key laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University , Beijing, China ., Warnich L; 33 Faculty of Science, Stellenbosch University , Stellenbosch, South Africa ., Wonkam A; 11 Division of Human Genetics, Department of Pathology & Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town , South Africa ., Yıldırım YZ; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Yılmaz İ; 34 Faculty of Arts and Sciences, Department of Chemistry, İnönü University , Malatya, Turkey ., Sınav A; 1 Faculty of Medicine and Office of the President, SANKO University , Gaziantep, Turkey ., Hekim N; 24 Independent Scholars, Istanbul, Turkey .

Publikováno v: Omics : a journal of integrative biology [OMICS] 2016 Apr; Vol. 20 (4), pp. 259-62.