The pharmacokinetics, distribution and degradation of human recombinant interleukin 1 beta in normal rats

Autor: Reimers, J, Wogensen, L D, Welinder, B, Hejnaes, K R, Poulsen, S S, Nilsson, P, Nerup, J

Publikováno v: Reimers, J, Wogensen, L D, Welinder, B, Hejnaes, K R, Poulsen, S S, Nilsson, P & Nerup, J 1991, ' The pharmacokinetics, distribution and degradation of human recombinant interleukin 1 beta in normal rats ', Scandinavian Journal of Immunology, vol. 34, no. 5, pp. 597-610 .

Based upon in vivo rat experiments it was recently suggested that interleukin 1 in the circulation may be implicated in the initial events of beta-cell destruction leading to insulin-dependent diabetes mellitus (IDDM) in humans. The aim of the presen

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https://pure.au.dk/portal/da/publications/the-pharmacokinetics-distribution-and-degradation-of-human-recombinant-interleukin-1-beta-in-normal-rats(6292b987-8cc2-4ae5-9511-14dc98877a5b).html

Comparison of Biological and Immunological Activities of Human Monocyte--Derived Interleukin 1β and Human Recombinant Interleukin 1β.

Autor: Mølvig, J., Sehested Hansen, B., Worsaae, H., HejnÆs, K. R., Helle, M., Dalbøge, H., Nerup, J.

Publikováno v: Scandinavian Journal of Immunology; Feb1990, Vol. 31 Issue 2, p225-235, 11p

New strategy for the design of ligands for the purification of pharmaceutical proteins by affinity chromatography

Autor: Sproule, K., Morrill, P., Pearson, J. C., Burton, S. J., Hejnaes, K. R., Valore, H., Ludvigsen, S., Lowe, C. R.

Publikováno v: Journal of Chromatography B: Biomedical Sciences and Applications; 2000, Vol. 740 Issue: 1 p17-33, 17p

Transfer of Type 1 (insulin-dependent) diabetes mellitus associated autoimmunity to mice with severe combined immunodeficiency (SCID)

Autor: Petersen, J. S., Marshall, M. O., Bækkeskov, S., Hejnæs, K. R., Høier-Madsen, M., Dyrberg, T.

Pancreatic beta-cell destruction and development of Type 1 (insulin-dependent) diabetes mellitus are associated with circulating islet cell antibodies. Mice with severe combined immunodeficiency (SCID mice) were reconstituted with peripheral blood mo

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https://infoscience.epfl.ch/record/214309

Interleukin-1beta induced changes in the protein expression of rat islets: a computerized database.

Autor: Andersen HU; Steno Diabetes Center, Gentofte, Denmark., Fey SJ, Larsen PM, Nawrocki A, Hejnaes KR, Mandrup-Poulsen T, Nerup J

Publikováno v: Electrophoresis [Electrophoresis] 1997 Oct; Vol. 18 (11), pp. 2091-103.