Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hejian Guo"'
Publikováno v:
Current Drug Delivery. 19:32-40
Background: Exenatide(EXE) is an anti-hyperglycemic agent approved for treating type 2 diabetes by the Food and Drug Administration(FDA). However, twice-daily injection of exenatide is inconvenient for most of the patients. Objective: In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ac85c68f821a2138de5884ff702ffd
https://doi.org/10.2174/1567201818666210614100603
https://doi.org/10.2174/1567201818666210614100603
Autor:
Lisi Qi, Leilei Hao, Hejian Guo, Xinquan Liu, Caiyun Li, Dianrui Zhang, Tingting Li, Jingjing Luan, Qiang Zhang
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 117:258-266
Amoitone B, a natural agonist to Nur77, is a promising anticancer drug. However, its application is seriously restricted due to the water-insolubility and short biological half-life. Amoitone B nanocrystals (AmB-NC) were formulated by microfluidizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f3d00887c85ec29c024d0ff8e6fdf0
https://doi.org/10.1016/j.colsurfb.2014.02.042
https://doi.org/10.1016/j.colsurfb.2014.02.042
Autor:
Qiang Zhang, Caiyun Li, Tingting Li, Yuanyuan Guo, Guangpu Liu, Leilei Hao, Hejian Guo, Dandan Zheng, Dianrui Zhang
Publikováno v:
Journal of Microencapsulation. 31:573-578
Bovine serum albumin (BSA) nanoparticle is a promising drug carrier system. Oridonin (ORI)-loaded galactosylated BSA nanoparticle (ORI-GB-NP) was prepared for liver targeting delivery of ORI. This work was designed to investigate the in vitro release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62705f95d7c93ebe0b5df085630ac5b0
https://doi.org/10.3109/02652048.2014.898705
https://doi.org/10.3109/02652048.2014.898705
Autor:
Leilei Hao, Hejian Guo, Tingting Li, Qiang Zhang, Caiyun Li, Jingyi Shen, Dianrui Zhang, Guangpu Liu, Lejiao Jia, Dandan Zheng, Yuanyuan Guo
Publikováno v:
International Journal of Pharmaceutics. 458:31-38
A novel polymer, i.e. galactosylated O-carboxymethyl chitosan-graft-stearic acid (Gal-OCMC-g-SA) was synthesized for liver targeting delivery of doxorubicin. The chemical structure was characterized by FT-IR, (1)H NMR and elemental analysis. Gal-OCMC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9285a2ab17dc90a7c79a2b8652c0a7
https://doi.org/10.1016/j.ijpharm.2013.10.020
https://doi.org/10.1016/j.ijpharm.2013.10.020
Autor:
Caiyun Li, Lisi Qi, Qiang Zhang, Leilei Hao, Hejian Guo, Dianrui Zhang, Xinquan Liu, Jingjing Luan
Publikováno v:
Drug Delivery. 20:324-330
Amoitone B, a novel compound chemically synthesized as the analogue of cytosporone B, has been proved to own superior affinity with Nur77 than its parent compound and exhibit notable anticancer activity. However, its application is seriously restrict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baa3550e373a3db28fa72720850bb24
https://doi.org/10.3109/10717544.2013.835007
https://doi.org/10.3109/10717544.2013.835007
Autor:
Yue Liu, Lejiao Jia, Jingyi Shen, Dandan Zheng, Hejian Guo, Xiaona Tian, Qiang Zhang, Caiyun Li, Hongxiang Lou, Cunxian Duan, Dianrui Zhang, Yang Jiao, Guangpu Liu
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 102:620-626
Riccardin D (RD) is a novel compound extracted from Chinese liverwort Marchantia polymorpha L. It exhibits various anticancer activities and can be used during lung cancer treatment. However, the compound's low solubility hinders its development. Rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3783d252db7e1e0a77c3c09357816212
https://doi.org/10.1016/j.colsurfb.2012.09.006
https://doi.org/10.1016/j.colsurfb.2012.09.006
Autor:
Zhenyu Li, Guangpu Liu, Xiaona Tian, Lisi Qi, Lejiao Jia, Jingyi Shen, Qiang Zhang, Hejian Guo, Dandan Zheng, Dianrui Zhang
Publikováno v:
Polym. Chem.. 4:156-165
The chitosan oligosaccharide-based disulfide-containing polyethylenimine derivative PEG-ss-COS-ss-PEI was synthesized and evaluated as a nonviral gene delivery carrier. The structure of the obtained polymers was confirmed by 1H NMR and FTIR. PEG-ss-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f97779c50f7fc2dbbfc4dec1cebbef7d
https://doi.org/10.1039/c2py20781h
https://doi.org/10.1039/c2py20781h
Autor:
Liu Yu, Lijiang Chen, Hejian Guo, Wang Yongjie, Hongsheng Liu, Jiaozhen Zhang, Xue-Lian Meng, Jinghong Rong
Publikováno v:
Drug development and industrial pharmacy. 43(1)
The objective of this study was to develop and evaluate the morphology, biodistribution and antitumor activity of bexarotene nanocrystals delivery system. The morphology was investigated using scanning electron microscopy (SEM), transmission electron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f03c7cf87901174b982c2e5b20713cc
https://pubmed.ncbi.nlm.nih.gov/27588517
https://pubmed.ncbi.nlm.nih.gov/27588517
Autor:
Caiyun Li, Qiang Zhang, Leilei Hao, Dianrui Zhang, Hejian Guo, Shengrong Guo, Feihu Wang, Dandan Zheng
Publikováno v:
Journal of Drug Targeting. 21:137-145
A novel micelle formulation of paclitaxel (PTX) has been prepared for the purpose of prolonging the blood circulation time as well as modifying the biodistribution of PTX in comparison to a current PTX formulation, Taxol injection. This work was desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad474b6dcb04a2660f95e7896aa8631
https://doi.org/10.3109/1061186x.2012.731067
https://doi.org/10.3109/1061186x.2012.731067
Autor:
Zhongxi Zhao, Yongchun Zhang, Ying Wang, Fang Zhang, Huiling Cheng, Caiyun Li, Hejian Guo, Guangpu Liu, Xinquan Liu
Publikováno v:
International journal of pharmaceutics. 502(1-2)
Nanoparticles based on the newly synthesized copolymers of linear PLGA blocked with two TPGS ends and galactosylated TPGS were successfully constructed as carriers of oridonin for liver-targeting. The novel copolymers were characterized by (1)H-NMR a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a399289121f0dc5a28a13d92f8aa646
https://pubmed.ncbi.nlm.nih.gov/26911417
https://pubmed.ncbi.nlm.nih.gov/26911417