Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation

Autor: Bérouti, Marleen, Lammens, Katja, Heiss, Matthias, Hansbauer, Larissa, Bauernfried, Stefan, Stöckl, Jan, Pinci, Francesca, Piseddu, Ignazio, Greulich, Wilhelm, Wang, Meiyue, Jung, Christophe, Fröhlich, Thomas, Carell, Thomas, Hopfner, Karl-Peter, Hornung, Veit

Publikováno v: In Immunity 9 July 2024 57(7):1482-1496

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Metabolization and Optimization of Carbocyclic 5-Aza-2′-Deoxycytidine

Autor: Peev, Elsa, Heiss, Matthias, Aumer, Tina, Sommermann, Corinna, Carell, Thomas

Acute myeloblastic leukaemia (AML) is a type of cancer affecting the cells of the bone marrow, preventing the normal production of blood cells. When a person is affected, the prognosis is poor. Whether due to late diagnosis or lack of more specific t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069a9ae5bf7596cde2b53c6240fb43e0

Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo

Autor: Heiss, Matthias, Hagelskamp, Felix, Marchand, Virginie, Motorin, Yuri, Kellner, Stefanie

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.389. ⟨10.1038/s41467-020-20576-4⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Recently, studies about RNA modification dynamics in human RNAs are among the most controversially discussed. As a main reason, we identified the unavailability of a technique which allows the investigation of the temporal processing of RNA transcrip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::052a68911456250f955009a8f906b0d4
http://europepmc.org/articles/PMC7810713

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