Chronic testosterone deficiency increases late inward sodium current and promotes triggered activity in ventricular myocytes from aging male mice.

Autor: Banga S; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada., Mishra M; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada., Heinze-Milne SD; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada., Jansen HJ; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada., Rose RA; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada., Howlett SE; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.; Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Publikováno v: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2023 Aug 01; Vol. 325 (2), pp. H264-H277. Date of Electronic Publication: 2023 Jun 30.

Serum testosterone concentrations are not associated with frailty in naturally ageing and testosterone-deficient older C57Bl/6 mice.

Autor: Heinze-Milne SD; Department of Pharmacology, Canada., Banga S; Department of Pharmacology, Canada., Godin J; Geriatric Medicine Research, Nova Scotia Health Authority, NS, Canada., Howlett SE; Department of Pharmacology, Canada; Department of Medicine (Geriatric Medicine), Dalhousie University, Halifax, NS, Canada. Electronic address: susan.howlett@dal.ca.

Publikováno v: Mechanisms of ageing and development [Mech Ageing Dev] 2022 Apr; Vol. 203, pp. 111638. Date of Electronic Publication: 2022 Feb 03.

Rodent models of frailty and their application in preclinical research.

Autor: Banga S; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada. Electronic address: sbanga@dal.ca., Heinze-Milne SD; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada. Electronic address: stefan.heinze.milne@dal.ca., Howlett SE; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada; Department of Medicine (Geriatric Medicine), Dalhousie University, Halifax, NS, Canada. Electronic address: susan.howlett@dal.ca.

Publikováno v: Mechanisms of ageing and development [Mech Ageing Dev] 2019 Apr; Vol. 179, pp. 1-10. Date of Electronic Publication: 2019 Jan 28.