Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Heinz von der Kammer"'
Autor:
Nikisha Carty, Nadège Berson, Karsten Tillack, Christina Thiede, Diana Scholz, Karsten Kottig, Yalda Sedaghat, Christina Gabrysiak, George Yohrling, Heinz von der Kammer, Andreas Ebneth, Volker Mack, Ignacio Munoz-Sanjuan, Seung Kwak
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123527 (2015)
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the huntingtin gene. Major pathological hallmarks of HD include inclusions of mutant huntingtin (mHTT) protein, loss of ne
Externí odkaz:
https://doaj.org/article/4aa04b67124f4f039732a83a0dacb17e
Autor:
André Manook, Behrooz H Yousefi, Antje Willuweit, Stefan Platzer, Sybille Reder, Andreas Voss, Marc Huisman, Markus Settles, Frauke Neff, Joachim Velden, Michael Schoor, Heinz von der Kammer, Hans-Jürgen Wester, Markus Schwaiger, Gjermund Henriksen, Alexander Drzezga
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31310 (2012)
In vivo imaging and quantification of amyloid-β plaque (Aβ) burden in small-animal models of Alzheimer's disease (AD) is a valuable tool for translational research such as developing specific imaging markers and monitoring new therapy approaches. M
Externí odkaz:
https://doaj.org/article/de3fe45cefe545f0bc8727bd2b9c0fdd
Autor:
Antje Willuweit, Joachim Velden, Robert Godemann, Andre Manook, Fritz Jetzek, Hartmut Tintrup, Gunther Kauselmann, Branko Zevnik, Gjermund Henriksen, Alexander Drzezga, Johannes Pohlner, Michael Schoor, John A Kemp, Heinz von der Kammer
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7931 (2009)
BACKGROUND: Transgenic mice expressing mutated amyloid precursor protein (APP) and presenilin (PS)-1 or -2 have been successfully used to model cerebral beta-amyloidosis, one of the characteristic hallmarks of Alzheimer's disease (AD) pathology. Howe
Externí odkaz:
https://doaj.org/article/dc990fc0a5e545ce871b31a4b5f6ed7d
Publikováno v:
Neurodegenerative Diseases. 11:1-12
Background: The dysfunction of protein degradation through the ubiquitin-proteasome system is now widely accepted as one of the causes of Alzheimer’s disease (AD), the pathological hallmarks of which are abnormal protein accumulation such as senile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d418307e275386996cd9f50f93abc3
https://doi.org/10.1159/000336016
https://doi.org/10.1159/000336016
Autor:
Volker Mack, Andreas Ebneth, Karsten Kottig, Diana Scholz, Karsten Tillack, Seung Kwak, George J. Yohrling, Ignacio Munoz-Sanjuan, Heinz Von Der Kammer, Nadege Berson, Christina Gabrysiak, Yalda Sedaghat, Nikisha Carty, Christina Thiede
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123527 (2015)
PLoS ONE
PLoS ONE
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the huntingtin gene. Major pathological hallmarks of HD include inclusions of mutant huntingtin (mHTT) protein, loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45420b5ccab529b9a65df55732f53087
http://europepmc.org/articles/PMC4393127?pdf=render
http://europepmc.org/articles/PMC4393127?pdf=render
Autor:
Barbara Andresen, Heinz Von Der Kammer, Jaroslav Klaudiny, Manuel Mayhaus, Cüneyt Demiralay, Claudia Albrecht, Roger M. Nitsch
Publikováno v:
Annals of the New York Academy of Sciences. 920:305-308
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f79af582dd0b94ee7c1c9fb1751e6c
https://doi.org/10.1111/j.1749-6632.2000.tb06939.x
https://doi.org/10.1111/j.1749-6632.2000.tb06939.x
Autor:
Janna Enderich, Roger Nitsch, Michael Wegner, Heinz Von Der Kammer, Claudia Albrecht, Manuel Mayhaus
Publikováno v:
Journal of Biological Chemistry. 273:14538-14544
In order to search for genes that are activated by muscarinic acetylcholine receptors (mAChRs), we used an mRNA differential display approach in HEK293 cells expressing m1AChR. The zinc-finger transcription factor genes Egr-1, Egr-2, and Egr-3 were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3855db88b0b187ddcf842b569f371b8e
https://doi.org/10.1074/jbc.273.23.14538
https://doi.org/10.1074/jbc.273.23.14538
Publikováno v:
DNA and Cell Biology. 13:1137-1143
From a cDNA sequence, we have deduced the amino acid sequence for a human amyloid precursor-like protein (APPH) with > 92% identity to the CDEI binding protein (CDEBP) of the mouse and the fragmentary rat protein YWK-II of unknown function. Expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2efd5e7327471f230ee3795946c0699
https://doi.org/10.1089/dna.1994.13.1137
https://doi.org/10.1089/dna.1994.13.1137
Autor:
Alexander Drzezga, Stefan Platzer, Andreas Voss, M Settles, Michael Schoor, André Manook, Sybille Reder, Antje Willuweit, Markus Schwaiger, Heinz Von Der Kammer, Frauke Neff, Behrooz H. Yousefi, Gjermund Henriksen, Joachim Velden, Hans-Jürgen Wester, Marc C. Huisman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e31310 (2012)
PLoS ONE, Vol 7, Iss 3, p e31310 (2012)
In vivo imaging and quantification of amyloid-β plaque (Aβ) burden in small-animal models of Alzheimer's disease (AD) is a valuable tool for translational research such as developing specific imaging markers and monitoring new therapy approaches. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae076a17f982905bcf48f0d67e8d975
https://pubmed.ncbi.nlm.nih.gov/22427802
https://pubmed.ncbi.nlm.nih.gov/22427802
Publikováno v:
The European journal of neuroscience. 21(5)
Alzheimer's disease (AD) is characterized by a progressive degeneration of neurons along with deposition of amyloid plaques and the formation of neurofibrillary tangles. Neurodegeneration in AD follows both a spatial pattern of selective vulnerabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583fbf8d476ceffd562fd5fd5926e1c4
https://pubmed.ncbi.nlm.nih.gov/15813938
https://pubmed.ncbi.nlm.nih.gov/15813938