Výsledky vyhledávání - "Heinz Zettlmeisl"

Dopamine transporter-mediated cytotoxicity of 6-hydroxydopamine in vitro depends on expression of mutant α-synucleins related to Parkinson's disease

Autor: Stefan Liebau, Vera Lehmensiek, Heinz Zettlmeisl, T Lenk, Eva-Maria Tan, Johannes Schwarz, Alexander Storch

Publikováno v: Neurochemistry International. 48:329-340

6-Hydroxydopamine (6-OHDA) is widely used to produce animal models of Parkinson's disease (PD) by selectively destroying the nigro-striatal dopaminergic systems, but selective toxicity of 6-OHDA towards dopaminergic cells in vitro remains controversi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee0b24b3a6ed45f994008511fa5ad25
https://doi.org/10.1016/j.neuint.2005.11.008

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Catechol-O-methyltransferase inhibition protects against 3,4-dihydroxyphenylalanine (DOPA) toxicity in primary mesencephalic cultures: new insights into levodopa toxicity

Autor: Alexander Storch, Heinz Zettlmeisl, Markus Bareiss, Johannes Schwarz, Heike Blessing

Publikováno v: Neurochemistry international. 42(2)

Inhibition of catechol-O-methyltransferase (COMT) has protective effects on levodopa (L-DOPA), but not D-DOPA toxicity towards dopamine (DA) neurons in rat primary mesencephalic cultures [Mol. Pharmacol. 57 (2000) 589]. Here, we extend our recent stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26e64a908b603117e355a3c5413cf85
https://pubmed.ncbi.nlm.nih.gov/12421594

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