Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Heinz Josef Klümpen"'
Autor:
Max Seidensticker, Osman Öcal, Kerstin Schütte, Peter Malfertheiner, Thomas Berg, Christian Loewe, Heinz Josef Klümpen, Otto van Delden, Muzaffer Reha Ümütlü, Najib Ben Khaled, Enrico Narciso de Toni, Ricarda Seidensticker, Ali Aghdassi, Albert Tran, Jean-Pierre Bronowicki, Bora Peynircioglu, Bruno Sangro, Maciej Pech, Jens Ricke
Publikováno v:
JHEP Reports, Vol 5, Iss 5, Pp 100699- (2023)
Background & Aims: The aim of the study was to evaluate the efficacy and safety of adjuvant sorafenib treatment compared with placebo in patients with hepatocellular carcinoma who underwent local ablation. Methods: The SORAMIC trial is a randomised c
Externí odkaz:
https://doaj.org/article/50507419bb5c4a48b92f62fe7087d683
Autor:
Osman Öcal, Juozas Kupčinskas, Egidijus Morkunas, Holger Amthauer, Kerstin Schütte, Peter Malfertheiner, Heinz Josef Klümpen, Christian Sengel, Julia Benckert, Ricarda Seidensticker, Bruno Sangro, Moritz Wildgruber, Maciej Pech, Peter Bartenstein, Jens Ricke, Max Seidensticker
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Background To confirm the prognostic value of previously published baseline interleukin 6 (IL6) and IL8 cutoff values in survival and liver dysfunction in patients with advanced HCC undergoing 90Y radioembolization. Methods A total of 83 pat
Externí odkaz:
https://doaj.org/article/b832054cf65348e4be321b5fb11a5a14
Autor:
Jean-Yves Blay, Paolo Casali, Isabelle Ray-Coquard, Michael J. Seckl, Jourik Gietema, Wouter W. de Herder, Martyn Caplin, Heinz-Josef Klümpen, Olivier Glehen, Lucjan Wyrwicz, Robin Peeters, Lisa Licitra, Nicolas Girard, Sophie Piperno-Neumann, Ellen Kapiteijn, Ahmed Idbaih, Enrico Franceschi, Annalisa Trama, Anna-Maria Frezza, Peter Hohenberger, Nadia Hindi, Javier Martin-Broto, Johanna Schell, Muriel Rogasik, Stephane Lejeune, Kathy Oliver, Francesco de Lorenzo, Ariane Weinman
Publikováno v:
The Lancet Regional Health. Europe, Vol 39, Iss , Pp 100861- (2024)
Summary: About 500,000 patients with rare adult solid cancers (RASC) are diagnosed yearly in Europe. Delays and unequal quality of management impact negatively their survival. Since 2017, European reference networks (ERN) aim to improve the quality o
Externí odkaz:
https://doaj.org/article/4f20025ebba2481ba272e65734dc8627
Autor:
Matthew Ledenko, Samuel O. Antwi, Shiho Arima, Julia Driscoll, Junji Furuse, Heinz-Josef Klümpen, Finn Ole Larsen, David K. Lau, Annett Maderer, Alice Markussen, Markus Moehler, Lynn E. Nooijen, Walid L. Shaib, Niall C. Tebbutt, Thierry André, Makoto Ueno, Rachel Woodford, Changhoon Yoo, Mark M. Zalupski, Tushar Patel
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/d600a4255c654614935a6f7f40a8171d
Autor:
Job van Riet, Harmen J. G. van de Werken, Edwin Cuppen, Ferry A. L. M. Eskens, Margot Tesselaar, Linde M. van Veenendaal, Heinz-Josef Klümpen, Marcus W. Dercksen, Gerlof D. Valk, Martijn P. Lolkema, Stefan Sleijfer, Bianca Mostert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Metastatic and locally-advanced neuroendocrine neoplasms (aNEN) display heterogeneous clinical and genetic characteristics. Here, the authors investigate the mutational landscape of 85 aNEN by whole genome sequencing and identify distinct subpopulati
Externí odkaz:
https://doaj.org/article/c4e59c95fe6b477fbcc18e6c64953ba9
Autor:
Mariëtte E. G. Kranendonk, Wenzel M. Hackeng, G. Johan A. Offerhaus, Folkert H. M. Morsink, Geertruida N. Jonges, Gerard Groenewegen, Pieter-Jaap Krijtenburg, Heinz-Josef Klümpen, Wendy W. J. de Leng, Leendert H. J. Looijenga, Lodewijk A. A. Brosens
Publikováno v:
Diagnostic Pathology, Vol 15, Iss 1, Pp 1-8 (2020)
Abstract Background Molecular diagnostics can be decisive in the differential diagnosis between a somatic metastasis of type II testicular germ cell tumor (TGCT) or a second primary carcinoma. This is in line with recent recommendations from the Inte
Externí odkaz:
https://doaj.org/article/efe15965c1be49f0ab91aad0a62eea01
Autor:
Jeska A. Fritzsche, David M. de Jong, Jasmijn J.M.M. Borremans, Marco J. Bruno, Otto M. Van Delden, Joris I. Erdmann, Paul Fockens, Peter G.M. de Gooyer, Bas Groot Koerkamp, Heinz-Josef Klümpen, Adriaan Moelker, Nahid S.M. Montazeri, Lynn E. Nooijen, Cyriel Y. Ponsioen, Roy L.J. Van Wanrooij, Lydi M.J.W. van Driel, Rogier P. Voermans
Publikováno v:
HPB. John Wiley and Sons Inc.
HPB, 25(7), 798-806. John Wiley & Sons Inc.
Fritzsche, J A, de Jong, D M, Borremans, J J M M, Bruno, M J, van Delden, O M, Erdmann, J I, Fockens, P, de Gooyer, P G M, Groot Koerkamp, B, Klümpen, H-J, Moelker, A, Montazeri, N S M, Nooijen, L E, Ponsioen, C Y, van Wanrooij, R L J, van Driel, L M J W & Voermans, R P 2023, ' Long-term efficacy of metal versus plastic stents in inoperable perihilar cholangiocarcinoma; a multicenter retrospective propensity score matched comparison ', HPB, vol. 25, no. 7, pp. 798-806 . https://doi.org/10.1016/j.hpb.2023.03.011
HPB, 25(7), 798-806. John Wiley & Sons Inc.
Fritzsche, J A, de Jong, D M, Borremans, J J M M, Bruno, M J, van Delden, O M, Erdmann, J I, Fockens, P, de Gooyer, P G M, Groot Koerkamp, B, Klümpen, H-J, Moelker, A, Montazeri, N S M, Nooijen, L E, Ponsioen, C Y, van Wanrooij, R L J, van Driel, L M J W & Voermans, R P 2023, ' Long-term efficacy of metal versus plastic stents in inoperable perihilar cholangiocarcinoma; a multicenter retrospective propensity score matched comparison ', HPB, vol. 25, no. 7, pp. 798-806 . https://doi.org/10.1016/j.hpb.2023.03.011
BACKGROUND: For palliative drainage of inoperable perihilar cholangiocarcinoma (pCCA) uncovered metal stents are preferred over plastic stents. However, there is a lack of data on re-interventions at the long-term. The aim is to evaluate the potentia
Autor:
Yvonne Schuller, Marieke Biegstraaten, Carla E. M. Hollak, Heinz-Josef Klümpen, Christine C. Gispen-de Wied, Violeta Stoyanova-Beninska
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract Background Evaluation of evidence for efficacy of orphan medicinal products (OMPs) for rare malignancies may be hampered by the use of tumor measurements instead of clinical endpoints. This may cause efficacy data to not always match effecti
Externí odkaz:
https://doaj.org/article/54c1406d95344772a624b2f11cf50998
Autor:
Lynn E. Nooijen, Stijn Franssen, Carlijn I. Buis, Cornelis H.C. Dejong, Marcel den Dulk, Otto M. van Delden, Jan N. Ijzermans, Bas Groot Koerkamp, Geert Kazemier, Krijn van Lienden, Heinz-Josef Klümpen, Hendrien Kuipers, Bram Olij, Robert J. Porte, Erik A. Rauws, Rogier P. Voermans, Thomas M. van Gulik, Joris I. Erdmann, E. Roos, R.J. Coelen
Publikováno v:
HPB. John Wiley and Sons Inc.
HPB, 25(2), 210-217. John Wiley & Sons Inc.
Hpb, 25(2), 210-217. ELSEVIER SCI LTD
HPB, 25(2), 210-217. ELSEVIER SCI LTD
Nooijen, L E, Franssen, S, Buis, C I, Dejong, C H C, den Dulk, M, van Delden, O M, Ijzermans, J N, Groot Koerkamp, B, Kazemier, G, van Lienden, K, Klümpen, H-J, Kuipers, H, Olij, B, Porte, R J, Rauws, E A, Voermans, R P, van Gulik, T M, Erdmann, J I, Roos, E & Coelen, R J 2022, ' Long-term follow-up of a randomized trial of biliary drainage in perihilar cholangiocarcinoma ', HPB . https://doi.org/10.1016/j.hpb.2022.10.009
HPB, 25(2), 210-217. John Wiley & Sons Inc.
Hpb, 25(2), 210-217. ELSEVIER SCI LTD
HPB, 25(2), 210-217. ELSEVIER SCI LTD
Nooijen, L E, Franssen, S, Buis, C I, Dejong, C H C, den Dulk, M, van Delden, O M, Ijzermans, J N, Groot Koerkamp, B, Kazemier, G, van Lienden, K, Klümpen, H-J, Kuipers, H, Olij, B, Porte, R J, Rauws, E A, Voermans, R P, van Gulik, T M, Erdmann, J I, Roos, E & Coelen, R J 2022, ' Long-term follow-up of a randomized trial of biliary drainage in perihilar cholangiocarcinoma ', HPB . https://doi.org/10.1016/j.hpb.2022.10.009
BACKGROUND AND AIMS: The DRAINAGE trial was a randomized controlled trial comparing preoperative endoscopic (EBD) and percutaneous biliary drainage (PTBD) in patients with potentially resectable, perihilar cholangiocarcinoma (pCCA). The aim of this s
Autor:
Roos Achterbergh, Laureen A. Lammers, Heinz-Josef Klümpen, Ron A. A. Mathôt, Johannes A. Romijn
Publikováno v:
Therapeutic drug monitoring, 44(6), 797-804. Lippincott Williams and Wilkins
Achterbergh, R, Lammers, L A, Klümpen, H-J, Mathôt, R A A & Romijn, J A 2022, ' Short-Term High-Fat Diet Alters Acetaminophen Metabolism in Healthy Individuals ', Therapeutic Drug Monitoring, vol. 44, no. 6, pp. 797-804 . https://doi.org/10.1097/FTD.0000000000000993
Therapeutic Drug Monitoring, 44(6), 797-804. Lippincott Williams and Wilkins
Achterbergh, R, Lammers, L A, Klümpen, H-J, Mathôt, R A A & Romijn, J A 2022, ' Short-Term High-Fat Diet Alters Acetaminophen Metabolism in Healthy Individuals ', Therapeutic Drug Monitoring, vol. 44, no. 6, pp. 797-804 . https://doi.org/10.1097/FTD.0000000000000993
Therapeutic Drug Monitoring, 44(6), 797-804. Lippincott Williams and Wilkins
BACKGROUND: Acetaminophen is metabolized through a nontoxic sulfation and glucuronidation pathway and toxic oxidation pathway (via CYP2E1 and CYP1A2). A short-term high-fat diet induces alterations in the steatotic liver and may alter hepatic drug en