Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Heinz H. Coenen"'
Autor:
Heinz H. Coenen, Antony D. Gee, Michael Adam, Gunnar Antoni, Cathy S. Cutler, Yasuhisa Fujibayashi, Jae Min Jeong, Robert H. Mach, Thomas L. Mindt, Victor W. Pike, Albert D. Windhorst
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-5 (2019)
Externí odkaz:
https://doaj.org/article/efd24b773fec4e6981257949ef7e763c
Publikováno v:
Molecules, Vol 20, Iss 1, Pp 470-486 (2014)
Substituted phenylpiperazines are often neuropharmacologically active compounds and in many cases are essential pharmacophores of neuroligands for different receptors such as D2-like dopaminergic, serotoninergic and other receptors. Nucleophilic, no-
Externí odkaz:
https://doaj.org/article/126640cd34de49569df08967981a4abc
Synthesis of No-Carrier-Added 4-[18F]Fluorophenol from 4-Benzyloxyphenyl-(2-thienyl)iodonium Bromide
Publikováno v:
Molecules, Vol 16, Iss 9, Pp 7621-7626 (2011)
4-[18F]Fluorophenol is a versatile synthon for the synthesis of more complex radiopharmaceuticals bearing a 4-[18F]fluorophenoxy moiety. In order to prepare 4-[18F]fluorophenol in no-carrier-added (n.c.a.) form only a nucleophilic labelling method st
Externí odkaz:
https://doaj.org/article/edec75fee1844a1997664bda37f7ade8
Autor:
Marc D. Piroth, Sarah Liebenstund, Norbert Galldiks, Gabriele Stoffels, Nadim J. Shah, Michael J. Eble, Heinz H. Coenen, Karl-Josef Langen
Publikováno v:
Molecular Imaging, Vol 12 (2013)
Monitoring of radiochemotherapy (RCX) in patients with glioblastoma is difficult because unspecific alterations in magnetic resonance imaging with contrast enhancement can mimic tumor progression. Changes in tumor to brain ratios (TBRs) in positron e
Externí odkaz:
https://doaj.org/article/741d289292804691b808625c1dd0aad6
Publikováno v:
Molecules, Vol 21, Iss 9, p 1160 (2016)
Nitric oxide (NO), an important multifunctional signaling molecule, is produced by three isoforms of NO-synthase (NOS) and has been associated with neurodegenerative disorders. Selective inhibitors of the subtypes iNOS (inducible) or nNOS (neuronal)
Externí odkaz:
https://doaj.org/article/397817a959e74ffeadf333d9b3d6b479
Autor:
Christian Filß, Felix M. Mottaghy, Heinz H. Coenen, Philipp Lohmann, Carina Stegmayr, Karl-Josef Langen, Alexander Heinzel, Gabriele Stoffels, Antje Willuweit, Johannes Ermert, Norbert Galldiks
Publikováno v:
Nuclear medicine and biology 92, 78-84 (2021). doi:10.1016/j.nucmedbio.2020.02.006
The diagnostic potential of PET using the amino acid analogue O-(2-[F-18]fluoroethyl)-L-tyrosine ([F-18]FET) in brain tumor diagnostics has been proven in many studies during the last two decades and is still the subject of multiple studies every yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35724cea3b91ab4247123765e56f764
https://doi.org/10.1016/j.nucmedbio.2020.02.006
https://doi.org/10.1016/j.nucmedbio.2020.02.006
Autor:
Sabrina Kreft, Heinz H. Coenen, Johnny Castillo Meleán, Dominik Krupp, Johannes Ermert, Daniel Modemann, Swen Humpert, Isabel Kern
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:380-392
A reaction pathway via oxidation of [18 F]fluorobenzaldehydes offers a very useful tool for the no-carrier-added radiosynthesis of [18 F]fluorophenols, a structural motive of several potential radiopharmaceuticals. A considerably improved chemoselect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f24889907a949aef90255533e3195f8
https://doi.org/10.1002/jlcr.3740
https://doi.org/10.1002/jlcr.3740
Autor:
Michael T. Barbe, Heinz H. Coenen, Karl-Josef Langen, Gabriele Stoffels, Norbert Galldiks, Lars Timmermann, Gereon R. Fink, Michael Sommerauer, Antje Willuweit, Michael Schroeter
Publikováno v:
Nuclear medicine communications 40(4), 383-387 (2019). doi:10.1097/MNM.0000000000000982
Objectives This study aimed to investigate whether the amino acid PET tracer cis-4-[18F]fluoro-D-proline [D-cis-[18F]FPro] shows increased uptake in the basal ganglia of patients with neurodegenerative akinetic-rigid parkinsonism. D-Cis-[18F]FPro is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29706f5326335ac9dfc165d4af374f7
https://doi.org/10.1097/mnm.0000000000000982
https://doi.org/10.1097/mnm.0000000000000982
Autor:
Antje Willuweit, Nadim Jon Shah, Stefanie Geisler, Philipp Lohmann, Heinz H. Coenen, Michael Sabel, Carina Stegmayr, Nicole Niemitz, Marion Rapp, Norbert Galldiks, Gabriele Stoffels, Christian Filss, Karl-Josef Langen
Publikováno v:
Journal of Nuclear Medicine. 60:1373-1379
Assessment of residual tumor after resection of cerebral gliomas can be difficult with MRI and may be improved by amino acid PET. The aim of this experimental study was to investigate uptake of 2-18F-fluoroethyl-l-tyrosine (18F-FET) and l-[methyl-3H]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ab99bacc98d34368b1c6356f466593e
https://doi.org/10.2967/jnumed.119.225680
https://doi.org/10.2967/jnumed.119.225680
Publikováno v:
Dalton Transactions. 48:3003-3008
trans-1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid (CDTA) labelled with a mixture of paramagnetic 55Mn(ii) and β+-emitting 52gMn(ii) offers access to bimodal Positron Emission Tomography/Magnetic Resonance (PET/MR) tracers. To enhance the numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9454f78661843b93e03f2abff218b84b
https://doi.org/10.1039/c8dt04996c
https://doi.org/10.1039/c8dt04996c