Effects of magnetic fields of up to 9.4 T on resolution and contrast of PET images as measured with an MR-BrainPET.

Autor: N Jon Shah, Hans Herzog, Christoph Weirich, Lutz Tellmann, Joachim Kaffanke, Liliana Caldeira, Elena Rota Kops, Syed M Qaim, Heinz H Coenen, Hidehiro Iida

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e95250 (2014)

Simultaneous, hybrid MR-PET is expected to improve PET image resolution in the plane perpendicular to the static magnetic field of the scanner. Previous papers have reported this either by simulation or experiment with simple sources and detector arr

Externí odkaz: https://doaj.org/article/fe93ea3baa8c49c89b0dde67d7dcbc4e

Current trends in the use of O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) in neurooncology

Autor: Christian Filß, Felix M. Mottaghy, Heinz H. Coenen, Philipp Lohmann, Carina Stegmayr, Karl-Josef Langen, Alexander Heinzel, Gabriele Stoffels, Antje Willuweit, Johannes Ermert, Norbert Galldiks

Publikováno v: Nuclear medicine and biology 92, 78-84 (2021). doi:10.1016/j.nucmedbio.2020.02.006

The diagnostic potential of PET using the amino acid analogue O-(2-[F-18]fluoroethyl)-L-tyrosine ([F-18]FET) in brain tumor diagnostics has been proven in many studies during the last two decades and is still the subject of multiple studies every yea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35724cea3b91ab4247123765e56f764
https://doi.org/10.1016/j.nucmedbio.2020.02.006

Baeyer-Villiger oxidation tuned to chemoselective conversion of non-activated [18 F]fluorobenzaldehydes to [18 F]fluorophenols

Autor: Sabrina Kreft, Heinz H. Coenen, Johnny Castillo Meleán, Dominik Krupp, Johannes Ermert, Daniel Modemann, Swen Humpert, Isabel Kern

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 62:380-392

A reaction pathway via oxidation of [18 F]fluorobenzaldehydes offers a very useful tool for the no-carrier-added radiosynthesis of [18 F]fluorophenols, a structural motive of several potential radiopharmaceuticals. A considerably improved chemoselect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f24889907a949aef90255533e3195f8
https://doi.org/10.1002/jlcr.3740

Treatment-Related Uptake of O-(2-18F-Fluoroethyl)-l-Tyrosine and l-[Methyl-3H]-Methionine After Tumor Resection in Rat Glioma Models

Autor: Antje Willuweit, Nadim Jon Shah, Stefanie Geisler, Philipp Lohmann, Heinz H. Coenen, Michael Sabel, Carina Stegmayr, Nicole Niemitz, Marion Rapp, Norbert Galldiks, Gabriele Stoffels, Christian Filss, Karl-Josef Langen

Publikováno v: Journal of Nuclear Medicine. 60:1373-1379

Assessment of residual tumor after resection of cerebral gliomas can be difficult with MRI and may be improved by amino acid PET. The aim of this experimental study was to investigate uptake of 2-18F-fluoroethyl-l-tyrosine (18F-FET) and l-[methyl-3H]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ab99bacc98d34368b1c6356f466593e
https://doi.org/10.2967/jnumed.119.225680

Expanding PET-applications in life sciences with positron-emitters beyond fluorine-18

Autor: Heinz H. Coenen, Johannes Ermert

Publikováno v: Nuclear medicine and biology 92, 241–269 (2021). doi:10.1016/j.nucmedbio.2020.07.003 special issue: "A Special Issue dedicated to Professor Bill Eckelman, Editor-in-Chief of NMB 1985 to 2017"

Positron emission tomography (PET) has become an indispensable diagnostic tool in modern nuclear medical diagnostics. Its outstanding molecular imaging features allow repetitive studies on one individual and with high sensitivity, though no interfere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16757a13967a6b53e2cec78b932e4b4a
https://hdl.handle.net/2128/27212