Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Heinz H, Coenen"'
Autor:
Heinz H. Coenen, Antony D. Gee, Michael Adam, Gunnar Antoni, Cathy S. Cutler, Yasuhisa Fujibayashi, Jae Min Jeong, Robert H. Mach, Thomas L. Mindt, Victor W. Pike, Albert D. Windhorst
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-5 (2019)
Externí odkaz:
https://doaj.org/article/efd24b773fec4e6981257949ef7e763c
Publikováno v:
Molecules, Vol 20, Iss 1, Pp 470-486 (2014)
Substituted phenylpiperazines are often neuropharmacologically active compounds and in many cases are essential pharmacophores of neuroligands for different receptors such as D2-like dopaminergic, serotoninergic and other receptors. Nucleophilic, no-
Externí odkaz:
https://doaj.org/article/126640cd34de49569df08967981a4abc
Autor:
Christian Filß, Felix M. Mottaghy, Heinz H. Coenen, Philipp Lohmann, Carina Stegmayr, Karl-Josef Langen, Alexander Heinzel, Gabriele Stoffels, Antje Willuweit, Johannes Ermert, Norbert Galldiks
Publikováno v:
Nuclear medicine and biology 92, 78-84 (2021). doi:10.1016/j.nucmedbio.2020.02.006
The diagnostic potential of PET using the amino acid analogue O-(2-[F-18]fluoroethyl)-L-tyrosine ([F-18]FET) in brain tumor diagnostics has been proven in many studies during the last two decades and is still the subject of multiple studies every yea
Synthesis of No-Carrier-Added 4-[18F]Fluorophenol from 4-Benzyloxyphenyl-(2-thienyl)iodonium Bromide
Publikováno v:
Molecules, Vol 16, Iss 9, Pp 7621-7626 (2011)
4-[18F]Fluorophenol is a versatile synthon for the synthesis of more complex radiopharmaceuticals bearing a 4-[18F]fluorophenoxy moiety. In order to prepare 4-[18F]fluorophenol in no-carrier-added (n.c.a.) form only a nucleophilic labelling method st
Externí odkaz:
https://doaj.org/article/edec75fee1844a1997664bda37f7ade8
Autor:
Sabrina Kreft, Heinz H. Coenen, Johnny Castillo Meleán, Dominik Krupp, Johannes Ermert, Daniel Modemann, Swen Humpert, Isabel Kern
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:380-392
A reaction pathway via oxidation of [18 F]fluorobenzaldehydes offers a very useful tool for the no-carrier-added radiosynthesis of [18 F]fluorophenols, a structural motive of several potential radiopharmaceuticals. A considerably improved chemoselect
Autor:
Michael T. Barbe, Heinz H. Coenen, Karl-Josef Langen, Gabriele Stoffels, Norbert Galldiks, Lars Timmermann, Gereon R. Fink, Michael Sommerauer, Antje Willuweit, Michael Schroeter
Publikováno v:
Nuclear medicine communications 40(4), 383-387 (2019). doi:10.1097/MNM.0000000000000982
Objectives This study aimed to investigate whether the amino acid PET tracer cis-4-[18F]fluoro-D-proline [D-cis-[18F]FPro] shows increased uptake in the basal ganglia of patients with neurodegenerative akinetic-rigid parkinsonism. D-Cis-[18F]FPro is
Autor:
Antje Willuweit, Nadim Jon Shah, Stefanie Geisler, Philipp Lohmann, Heinz H. Coenen, Michael Sabel, Carina Stegmayr, Nicole Niemitz, Marion Rapp, Norbert Galldiks, Gabriele Stoffels, Christian Filss, Karl-Josef Langen
Publikováno v:
Journal of Nuclear Medicine. 60:1373-1379
Assessment of residual tumor after resection of cerebral gliomas can be difficult with MRI and may be improved by amino acid PET. The aim of this experimental study was to investigate uptake of 2-18F-fluoroethyl-l-tyrosine (18F-FET) and l-[methyl-3H]
Publikováno v:
Dalton Transactions. 48:3003-3008
trans-1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid (CDTA) labelled with a mixture of paramagnetic 55Mn(ii) and β+-emitting 52gMn(ii) offers access to bimodal Positron Emission Tomography/Magnetic Resonance (PET/MR) tracers. To enhance the numbe
Autor:
N Jon Shah, Hans Herzog, Christoph Weirich, Lutz Tellmann, Joachim Kaffanke, Liliana Caldeira, Elena Rota Kops, Syed M Qaim, Heinz H Coenen, Hidehiro Iida
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95250 (2014)
Simultaneous, hybrid MR-PET is expected to improve PET image resolution in the plane perpendicular to the static magnetic field of the scanner. Previous papers have reported this either by simulation or experiment with simple sources and detector arr
Externí odkaz:
https://doaj.org/article/fe93ea3baa8c49c89b0dde67d7dcbc4e
Autor:
Heinz H. Coenen, Johannes Ermert
Publikováno v:
Nuclear medicine and biology 92, 241–269 (2021). doi:10.1016/j.nucmedbio.2020.07.003 special issue: "A Special Issue dedicated to Professor Bill Eckelman, Editor-in-Chief of NMB 1985 to 2017"
Positron emission tomography (PET) has become an indispensable diagnostic tool in modern nuclear medical diagnostics. Its outstanding molecular imaging features allow repetitive studies on one individual and with high sensitivity, though no interfere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16757a13967a6b53e2cec78b932e4b4a
https://hdl.handle.net/2128/27212
https://hdl.handle.net/2128/27212