Zobrazeno 1 - 10
of 684
pro vyhledávání: '"Heinz Feldmann"'
Autor:
David W. Hawman, Shanna S. Leventhal, Kimberly Meade-White, Amit Khandhar, Justin Murray, Jamie Lovaglio, Carl Shaia, Greg Saturday, Troy Hinkley, Jesse Erasmus, Heinz Feldmann
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne febrile illness with a wide geographic distribution. In recent years the geographic range of Crimean-Congo hemorrhagic fever virus (CCHFV) and its tick vector have increased, placing an
Externí odkaz:
https://doaj.org/article/ab14f955c4a64e3d9272d9bbe34d7b75
Autor:
Vanessa Monteil, Hyesoo Kwon, Lijo John, Cristiano Salata, Gustav Jonsson, Sabine U. Vorrink, Sofia Appelberg, Sonia Youhanna, Matheus Dyczynski, Alexandra Leopoldi, Nicole Leeb, Jennifer Volz, Astrid Hagelkruys, Max J. Kellner, Stéphanie Devignot, Georg Michlits, Michelle Foong-Sobis, Friedemann Weber, Volker M. Lauschke, Moritz Horn, Heinz Feldmann, Ulrich Elling, Josef M. Penninger, Ali Mirazimi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Marburg and Ebola filoviruses are two of the deadliest infectious agents and several outbreaks have occurred in the last decades. Although several receptors and co-receptors have been reported for Ebola virus, key host factors remain to be e
Externí odkaz:
https://doaj.org/article/138c2c1cad6c485e9bafa12b9c5adf5c
Autor:
Deepashri Rao, Kimberly Meade-White, Shanna Leventhal, Evan Mihalakakos, Aaron Carmody, Heinz Feldmann, David W. Hawman
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104839- (2023)
Summary: Background: Crimean-Congo haemorrhagic fever (CCHF) is a serious viral hemorrhagic fever caused by the CCHF virus (CCHFV). Spread by the bites of infected ticks or handling of viremic livestock, human disease is characterized by a non-specif
Externí odkaz:
https://doaj.org/article/8376ad720a87492293567c01503f90f0
Autor:
Joshua Marceau, David Safronetz, Cynthia Martellaro, Andrea Marzi, Kyle Rosenke, Heinz Feldmann
Publikováno v:
Viruses, Vol 16, Iss 2, p 279 (2024)
Orthohantaviruses may cause hemorrhagic fever with renal syndrome or hantavirus cardiopulmonary syndrome. Andes virus (ANDV) is the only orthohantavirus associated with human–human transmission. Therefore, emergency vaccination would be a valuable
Externí odkaz:
https://doaj.org/article/51d114e90f5e4a1abcf81c7b40f785c0
Autor:
Frances S. Li, Kathryn S. Carpentier, David W. Hawman, Cormac J. Lucas, Stephanie E. Ander, Heinz Feldmann, Thomas E. Morrison
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112418- (2023)
Summary: Arboviruses are public health threats that cause explosive outbreaks. Major determinants of arbovirus transmission, geographic spread, and pathogenesis are the magnitude and duration of viremia in vertebrate hosts. Previously, we determined
Externí odkaz:
https://doaj.org/article/2d0c7a1f21d4487fb3d8295abcdea33a
Autor:
Ami Patel, Kyle Rosenke, Elizabeth M. Parzych, Friederike Feldmann, Suman Bharti, Amanda J. Griffin, Blake Schouest, Matt Lewis, Jihae Choi, Neethu Chokkalingam, Viviane Machado, Brian J. Smith, Drew Frase, Ali R. Ali, Jamie Lovaglio, Brian Nguyen, Patrick W. Hanley, Susanne N. Walker, Ebony N. Gary, Abhijeet Kulkarni, Allison Generotti, Joseph R. Francica, Kim Rosenthal, Daniel W. Kulp, Mark T. Esser, Trevor R. F. Smith, Carl Shaia, David B. Weiner, Heinz Feldmann
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTCOVID-19 remains a major public health concern. Monoclonal antibodies have received emergency use authorization (EUA) for pre-exposure prophylaxis against COVID-19 among high-risk groups for treatment of mild to moderate COVID-19. In addition
Externí odkaz:
https://doaj.org/article/b981edf4969f4fdb9843528b197ac517
Autor:
Megan A O'Connor, David W Hawman, Kimberly Meade-White, Shanna Leventhal, Wenjun Song, Samantha Randall, Jacob Archer, Thomas B Lewis, Brieann Brown, Megan N Fredericks, Kaitlin R Sprouse, Hillary C Tunggal, Mara Maughan, Naoto Iwayama, Chul Ahrens, William Garrison, Solomon Wangari, Kathryn A Guerriero, Patrick Hanley, Jamie Lovaglio, Greg Saturday, David Veesler, Paul T Edlefsen, Amit P Khandhar, Heinz Feldmann, Deborah Heydenburg Fuller, Jesse H Erasmus
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011298 (2023)
The global SARS-CoV-2 pandemic prompted rapid development of COVID-19 vaccines. Although several vaccines have received emergency approval through various public health agencies, the SARS-CoV-2 pandemic continues. Emergent variants of concern, waning
Externí odkaz:
https://doaj.org/article/d4af23eb43be40bcaa467db922cd5121
Autor:
Kyle Rosenke, Matt C. Lewis, Friederike Feldmann, Eric Bohrnsen, Benjamin Schwarz, Atsushi Okumura, W. Forrest Bohler, Julie Callison, Carl Shaia, Catharine M. Bosio, Jamie Lovaglio, Greg Saturday, Michael A. Jarvis, Heinz Feldmann
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
The periodic emergence of SARS-CoV-2 variants of concern (VOCs) with unpredictable clinical severity and ability to escape preexisting immunity emphasizes the continued need for antiviral interventions. Two small molecule inhibitors, molnupiravir (MK
Externí odkaz:
https://doaj.org/article/8c4c6d11714643ca966ef175993be046
Histopathologic Characterization of Experimental Peracute SARS-CoV-2 Infection in the Syrian Hamster
Autor:
Chad S. Clancy, Kimberly Meade-White, Carl Shaia, Greg Saturday, Heinz Feldmann, Kyle Rosenke
Publikováno v:
Veterinary Sciences, Vol 10, Iss 9, p 536 (2023)
Coronavirus Infectious Disease 2019 (COVID-19) initiated a global pandemic that thus far has resulted in the death of over 6.5 million people internationally. Understanding the viral tropism during the initial, subclinical phase of infection is criti
Externí odkaz:
https://doaj.org/article/3af8442529d84d9b9fd3237d94369e9d
Autor:
Emmie de Wit, Friederike Feldmann, Jacqueline Cronin, Kerry Goldin, Reinaldo Mercado-Hernandez, Brandi N. Williamson, Kimberly Meade-White, Atsushi Okumura, Julie Callison, Sarah Weatherman, Rebecca Rosenke, Victoria A. Avanzato, Jamie Lovaglio, Dana P. Scott, Andrea Marzi, Heinz Feldmann
Publikováno v:
EBioMedicine, Vol 87, Iss , Pp 104405- (2023)
Summary: Background: Nipah virus (NiV) causes recurrent outbreaks of lethal respiratory and neurological disease in Southeast Asia. The World Health Organization considers the development of an effective vaccine against NiV a priority. Methods: We pr
Externí odkaz:
https://doaj.org/article/dfff7aaf39d542d6855906a23c3664cd