Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Heinz D, Osiewacz"'
Autor:
Heinz D. Osiewacz
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
Biomembranes fulfill several essential functions. They delimitate cells and control the exchange of compounds between cells and the environment. They generate specialized cellular reaction spaces, house functional units such as the respiratory chain
Externí odkaz:
https://doaj.org/article/1473b5cd007b484482833a131e5e4c3f
Autor:
Jana Key, Suzana Gispert, Arvind Reddy Kandi, Daniela Heinz, Andrea Hamann, Heinz D. Osiewacz, David Meierhofer, Georg Auburger
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 241 (2024)
The serine peptidase CLPP is conserved among bacteria, chloroplasts, and mitochondria. In humans and mice, its loss causes Perrault syndrome, which presents with growth deficits, infertility, deafness, and ataxia. In the filamentous fungus Podospora
Externí odkaz:
https://doaj.org/article/60dd4f20399d43fa909a042f34ffada4
Publikováno v:
Journal of Fungi, Vol 8, Iss 10, p 1015 (2022)
The formation of fruiting bodies is a highly regulated process that requires the coordinated formation of different cell types. By analyzing developmental mutants, many developmental factors have already been identified. Yet, a complete understanding
Externí odkaz:
https://doaj.org/article/df68ad74507a447c9bb54d192305ada3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Organismic aging is known to be controlled by genetic and environmental traits. Pathways involved in the control of cellular metabolism play a crucial role. Previously, we identified a role of PaCLPP, a mitochondrial matrix protease, in the control o
Externí odkaz:
https://doaj.org/article/bf9024ab10f84076a1b8615301de7690
Publikováno v:
Cells, Vol 11, Iss 3, p 519 (2022)
The maintenance of cellular homeostasis over time is essential to avoid the degeneration of biological systems leading to aging and disease. Several interconnected pathways are active in this kind of quality control. One of them is autophagy, the vac
Externí odkaz:
https://doaj.org/article/f6c054414ffa411ab2808e9ffcf9aadf
Publikováno v:
Microbial Cell, Vol 5, Iss 4, Pp 198-207 (2018)
In aerobic organisms, mitochondrial F1Fo-ATP-synthase is the major site of ATP production. Beside this fundamental role, the protein complex is involved in shaping and maintenance of cristae. Previous electron microscopic studies identified the disso
Externí odkaz:
https://doaj.org/article/cb1bd9a91ee747db9a872edc60d0d649
Autor:
Didac Carmona-Gutierrez, Maria Anna Bauer, Andreas Zimmermann, Andrés Aguilera, Nicanor Austriaco, Kathryn Ayscough, Rena Balzan, Shoshana Bar-Nun, Antonio Barrientos, Peter Belenky, Marc Blondel, Ralf J. Braun, Michael Breitenbach, William C. Burhans, Sabrina Büttner, Duccio Cavalieri, Michael Chang, Katrina F. Cooper, Manuela Côrte-Real, Vítor Costa, Christophe Cullin, Ian Dawes, Jörn Dengjel, Martin B. Dickman, Tobias Eisenberg, Birthe Fahrenkrog, Nicolas Fasel, Kai-Uwe Fröhlich, Ali Gargouri, Sergio Giannattasio, Paola Goffrini, Campbell W. Gourlay, Chris M. Grant, Michael T. Greenwood, Nicoletta Guaragnella, Thomas Heger, Jürgen Heinisch, Eva Herker, Johannes M. Herrmann, Sebastian Hofer, Antonio Jiménez-Ruiz, Helmut Jungwirth, Katharina Kainz, Dimitrios P. Kontoyiannis, Paula Ludovico, Stéphen Manon, Enzo Martegani, Cristina Mazzoni, Lynn A. Megeney, Chris Meisinger, Jens Nielsen, Thomas Nyström, Heinz D. Osiewacz, Tiago F. Outeiro, Hay-Oak Park, Tobias Pendl, Dina Petranovic, Stephane Picot, Peter Polčic, Mark Ramsdale, Mark Rinnerthaler, Patrick Rockenfeller, Christoph Ruckenstuhl, Raffael Schaffrath, Maria Segovia, Fedor F. Severin, Amir Sharon, Stephan J. Sigrist, Cornelia Sommer-Ruck, Maria João Sousa, Johan M. Thevelein, Karin Thevissen, Vladimir Titorenko, Michel B. Toledano, Mick Tuite, F.-Nora Vögtle, Benedikt Westermann, Joris Winderickx, Silke Wissing, Stefan Wölfl, Zhaojie J. Zhang, Richard Y. Zhao, Bing Zhou, Lorenzo Galluzzi, Guido Kroemer, Frank Madeo
Publikováno v:
Microbial Cell, Vol 5, Iss 1, Pp 4-31 (2018)
Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cellular demise. However, the investigation of yeast cell d
Externí odkaz:
https://doaj.org/article/7204719614c446e08c16d57347cd80b5
Publikováno v:
Cells, Vol 10, Iss 12, p 3319 (2021)
The accumulation of functionally impaired mitochondria is a key event in aging. Previous works with the fungal aging model Podospora anserina demonstrated pronounced age-dependent changes of mitochondrial morphology and ultrastructure, as well as alt
Externí odkaz:
https://doaj.org/article/4005e28e3d3349a3b0e57046f9009910
Publikováno v:
Cells, Vol 10, Iss 10, p 2775 (2021)
Mitochondria are ubiquitous organelles of eukaryotic organisms with a number of essential functions, including synthesis of iron-sulfur clusters, amino acids, lipids, and adenosine triphosphate (ATP). During aging of the fungal aging model Podospora
Externí odkaz:
https://doaj.org/article/5ff54ceb5fea4576877f81fe49ec1293
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background Autophagy is a conserved molecular pathway involved in the degradation and recycling of cellular components. It is active either as response to starvation or molecular damage. Evidence is emerging that autophagy plays a key role i
Externí odkaz:
https://doaj.org/article/892fe586ee054d62951184c26631dcc2