Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Heinz, Uwe"'
The late 1980s saw the dissolution of the Iron Curtain and the development of democracy in Eastern European countries that had been oppressed by a range of varieties of communist totalitarian regimes. In Germany, this development led to the abolition
In March 2014, the University of Delaware's Resident Ensemble Players staged the first Part of Goethe's Faust, adapted and directed by Heinz-Uwe Haus, which forms the centrepiece and raison d'être of this book. This book tracks the creative process
Autor:
Dettling, Heinz-Uwe1 heinz-uwe.dettling@de.ey.com
Publikováno v:
Pharmazeutische Industrie (Pharmind). 2023, Vol. 85 Issue 8, p746-754. 9p.
Autor:
Kumstel, Simone, Vasudevan, Praveen, Palme, Rupert, Zhang, Xianbin, Wendt, Edgar Heinz Uwe, David, Robert, Vollmar, Brigitte, Zechner, Dietmar
Publikováno v:
In Journal of Advanced Research January 2020 21:35-47
Autor:
Simone Kumstel, Praveen Vasudevan, Rupert Palme, Xianbin Zhang, Edgar Heinz Uwe Wendt, Robert David, Brigitte Vollmar, Dietmar Zechner
Publikováno v:
Journal of Advanced Research, Vol 21, Iss , Pp 35-47 (2020)
Prospective severity assessment is legally required in many countries to ensure high-quality research along with high welfare standards for laboratory animals. Mice and rats, the most common laboratory species, are prey animals that usually suppress
Externí odkaz:
https://doaj.org/article/26edb334e1344567b7979cf5ed6af03b
Autor:
Simone Kumstel, Tim Schreiber, Lea Goldstein, Jan Stenzel, Tobias Lindner, Markus Joksch, Xianbin Zhang, Edgar Heinz Uwe Wendt, Maria Schönrogge, Bernd Krause, Brigitte Vollmar, Dietmar Zechner
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266601 (2022)
Pancreatic cancer is the fourth leading cause of cancer death, with a 5-year survival rate of 10%. A stagnant high mortality rate over the last decades highlights the need for innovative therapeutic approaches. Pancreatic tumors pursue an altered met
Externí odkaz:
https://doaj.org/article/dd2a203bb1614ff2a19d323403d62670
Autor:
Steven R. Talbot, Simone Kumstel, Benjamin Schulz, Guanglin Tang, Ahmed Abdelrahman, Nico Seume, Edgar Heinz Uwe Wendt, Johanna Eichberg, Christine Häger, Andre Bleich, Brigitte Vollmar, Dietmar Zechner
Publikováno v:
Scientific Reports. 13
The fundament of an evidence-based severity assessment in laboratory animal science is reliable distress parameters. Many readouts are used to evaluate and determine animal distress and the severity of experimental procedures. Therefore, we analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc0442844e2c9aedd6d41d5f393488e
https://doi.org/10.1038/s41598-023-29623-8
https://doi.org/10.1038/s41598-023-29623-8
Blocking Autophagy in Cancer-Associated Fibroblasts Supports Chemotherapy of Pancreatic Cancer Cells
Autor:
Xianbin Zhang, Maria Schönrogge, Johanna Eichberg, Edgar Heinz Uwe Wendt, Simone Kumstel, Jan Stenzel, Tobias Lindner, Robert Jaster, Bernd Joachim Krause, Brigitte Vollmar, Dietmar Zechner
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
In this study we evaluated the interaction of pancreatic cancer cells, cancer-associated fibroblasts, and distinct drugs such as α-cyano-4-hydroxycinnamate, metformin, and gemcitabine. We observed that α-cyano-4-hydroxycinnamate as monotherapy or i
Externí odkaz:
https://doaj.org/article/83acb2a73d7342aaa426854788ae8c77
Autor:
Nico Seume, Brigitte Vollmar, Ahmed Abdelrahman, Edgar Heinz Uwe Wendt, Guanglin Tang, Nicole Ernst, Rupert Palme, Heike Janssen-Peters, Dietmar Zechner, Thomas Thum, Ke Xiao, Simone Kumstel
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Severity assessment of animal experiments is mainly conducted by using subjective parameters. A widely applicable biomarker to assess animal distress could contribute to an objective severity assessment in different animal models. Here, the distress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9653fd0897791275132366aaf46d4e
http://link.springer.com/article/10.1038/s41598-020-73972-7
http://link.springer.com/article/10.1038/s41598-020-73972-7