Výsledky vyhledávání - "Heintzelman GR"

Akademický článek

Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma.

Autor: Sturdivant JM; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States. Electronic address: jsturdivant@aeriepharma.com., Royalty SM; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States., Lin CW; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States., Moore LA; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States., Yingling JD; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States., Laethem CL; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States., Sherman B; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States., Heintzelman GR; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States., Kopczynski CC; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States., deLong MA; Aerie Pharmaceuticals, Inc., 4301 Emperor Boulevard, Suite 400, Durham, NC 27703, United States.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2016 May 15; Vol. 26 (10), pp. 2475-2480. Date of Electronic Publication: 2016 Apr 01.

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Akademický článek

In vivo characterization of a dual adenosine A2A/A1 receptor antagonist in animal models of Parkinson's disease.

Autor: Shook BC; Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Welsh and McKean Roads, P.O. Box 776, Spring House, Pennsylvania 19477, USA. bshook@its.jnj.com, Rassnick S, Osborne MC, Davis S, Westover L, Boulet J, Hall D, Rupert KC, Heintzelman GR, Hansen K, Chakravarty D, Bullington JL, Russell R, Branum S, Wells KM, Damon S, Youells S, Li X, Beauchamp DA, Palmer D, Reyes M, Demarest K, Tang Y, Rhodes K, Jackson PF

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2010 Nov 25; Vol. 53 (22), pp. 8104-15. Date of Electronic Publication: 2010 Oct 25.

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Akademický článek

Optimization of arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists.

Autor: Shook BC; Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Welsh and McKean Roads, PO Box 776, Spring House, PA 19477, United States. bshook@its.jnj.com, Rassnick S, Chakravarty D, Wallace N, Ault M, Crooke J, Barbay JK, Wang A, Leonard K, Powell MT, Alford V, Hall D, Rupert KC, Heintzelman GR, Hansen K, Bullington JL, Scannevin RH, Carroll K, Lampron L, Westover L, Russell R, Branum S, Wells K, Damon S, Youells S, Beauchamp D, Li X, Rhodes K, Jackson PF

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2010 May 01; Vol. 20 (9), pp. 2868-71. Date of Electronic Publication: 2010 Mar 07.

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Akademický článek

Methylene amine substituted arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists.

Autor: Shook BC; Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Welsh and McKean Roads, PO Box 776, Spring House, PA 19477, United States. bshook@its.jnj.com, Rassnick S, Hall D, Rupert KC, Heintzelman GR, Hansen K, Chakravarty D, Bullington JL, Scannevin RH, Magliaro B, Westover L, Carroll K, Lampron L, Russell R, Branum S, Wells K, Damon S, Youells S, Li X, Osbourne M, Demarest K, Tang Y, Rhodes K, Jackson PF

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2010 May 01; Vol. 20 (9), pp. 2864-7. Date of Electronic Publication: 2010 Mar 11.

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Akademický článek

Toward the development of a general chiral auxiliary. A total synthesis of (+)-tetronolide via a tandem ketene-trapping [4 + 2] cycloaddition strategy.

Autor: Boeckman RK Jr; Department of Chemistry, University of Rochester, P.O. Box 270216, Hutchison Hall, Rochester, New York 14627-0216, USA. rkb@rkbmac.chem.rochester.edu, Shao P, Wrobleski ST, Boehmler DJ, Heintzelman GR, Barbosa AJ

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2006 Aug 16; Vol. 128 (32), pp. 10572-88.

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Akademický článek

Imino Diels-Alder-Based Construction of a Piperidine A-Ring Unit for Total Synthesis of the Marine Hepatotoxin Cylindrospermopsin.

Autor: Heintzelman GR; Department of Chemistry, University of Calgary, 2500 University Drive, N.W., Calgary, Alberta T2N 1N4, Canada., Weinreb SM, Parvez M

Publikováno v: The Journal of organic chemistry [J Org Chem] 1996 Jul 12; Vol. 61 (14), pp. 4594-4599.

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