Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Heinrich Lellek"'
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Akademický článek
Population dynamics in colonizing vancomycin-resistant Enterococcus faecium isolated from immunosuppressed patients
Autor: Anna Both, Florian Kruse, Nadine Mirwald, Gefion Franke, Martin Christner, Jiabin Huang, Jan Lennart Hansen, Nicolaus Kröger, Laura Berneking, Heinrich Lellek, Martin Aepfelbacher, Holger Rohde
Publikováno v: Journal of Global Antimicrobial Resistance, Vol 28, Iss , Pp 267-273 (2022)
ABSTRACT: Objectives: Vancomycin-resistant Enterococcus faecium and Enterococcus faecalis (VRE) are a common cause of healthcare-associated infections. Whole genome sequencing–based typing methods yield the highest discriminatory power for outbreak
Externí odkaz: https://doaj.org/article/09de84112e7547d4b815973f6daa0243
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3
Population dynamics in colonizing vancomycin-resistant Enterococcus faecium isolated from immunosuppressed patients
Autor: Anna Both, Florian Kruse, Nadine Mirwald, Gefion Franke, Martin Christner, Jiabin Huang, Jan Lennart Hansen, Nicolaus Kröger, Laura Berneking, Heinrich Lellek, Martin Aepfelbacher, Holger Rohde
Publikováno v: Journal of global antimicrobial resistance. 28
Vancomycin-resistant Enterococcus faecium and Enterococcus faecalis (VRE) are a common cause of healthcare-associated infections. Whole genome sequencing-based typing methods yield the highest discriminatory power for outbreak surveillance in the hos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e7bac5b8835673c08d67e5e2d3e122
https://pubmed.ncbi.nlm.nih.gov/35134550
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4
Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples
Autor: Daniela Indenbirken, Martin Aepfelbacher, Marc Lütgehetmann, Heinrich Lellek, Malik Alawi, Adam Grundhoff, Thomas Meyer, Nicole Fischer, Michael Spohn
Publikováno v: Journal of Clinical Microbiology. 53:2238-2250
Unbiased nontargeted metagenomic RNA sequencing (UMERS) has the advantage to detect known as well as unknown pathogens and, thus, can significantly improve the detection of viral, bacterial, parasitic, and fungal sequences in public health settings.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afcb6e66ba6c342a5842962bfc76248f
https://doi.org/10.1128/jcm.02495-14
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5
Activation of Cell Surface Bound 20S Proteasome Inhibits Vascular Cell Growth and Arteriogenesis
Autor: Ziyang Zhang, Wulf D. Ito, Wolfgang Schaper, Hans-Günther Machens, Heribert Schunkert, Friedrich Buck, Natalie Lund, Heinrich Lellek, Andrea Kristina Horst, Thomas Meinertz
Publikováno v: BioMed Research International
BioMed Research International, Vol 2015 (2015)
Arteriogenesis is an inflammatory process associated with rapid cellular changes involving vascular resident endothelial progenitor cells (VR-EPCs). Extracellular cell surface bound 20S proteasome has been implicated to play an important role in infl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dd4f84657fe177b79765b691175d22
https://doi.org/10.1155/2015/719316
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6
Serum albumin level predicts survival of patients with gastrointestinal acute graft-versus-host disease after allogeneic stem cell transplantation
Autor: Haefaa Alchalby, Nicolaus Kröger, Christine Wolschke, Heinrich Lellek, Axel R. Zander, Ulrike Bacher, Ronja Veit, Tatjana Zabelina, Francis Ayuk, Lara Bussmann
Publikováno v: Annals of Hematology. 93:855-861
In a retrospective single-centre study, we analysed the prognostic impact of factors identifiable at initial diagnosis of acute GVHD (aGVHD). We retrospectively analysed 495 adult patients of whom 308 (62 %) developed acute GVHD (I-IV) and were inclu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240d1d80bd4458728964e8f238f28d7c
https://doi.org/10.1007/s00277-013-1957-0
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7
Effective prevention of GVHD using in vivo T-cell depletion with anti-lymphocyte globulin in HLA-identical or -mismatched sibling peripheral blood stem cell transplantation
Autor: Pein Um, Raissa Adjallé, Jürgen Berger, Randenborgh A, Heinrich Lellek, Christine Wolschke, Haefaa Alchalby, F Wortmann, Tatjana Zabelina, Axel R. Zander, Gitta Amtsfeld, N Kröger, F Ayuk, Evgeny Klyuchnikov, Schumacher S
Publikováno v: Bone Marrow Transplantation. 49:126-130
To investigate the impact of anti-lymphocyte globulin (ATG-Fresenius) as part of the HLA-sibling transplantation, we evaluated 238 patients (median age 48 years) with different diagnoses (AML, ALL, CML and lymphoproliferative disorders). A total of 7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd4c8978dea18025a30c33181ab559b
https://doi.org/10.1038/bmt.2013.143
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8
Donor choice according to age for allo-SCT for AML in complete remission
Autor: Tatjana Zabelina, Ulrike Bacher, Francis Ayuk, Haefaa Alchalby, Christine Wolschke, F Wortmann, Heinrich Lellek, Axel R. Zander, N Kröger
Publikováno v: Bone Marrow Transplantation. 48:1028-1032
In a retrospective study of 168 patients with AML in CR who underwent allo-SCT, we compare the impact of young unrelated donors (UD) vs older matched related donors (MRD) on 5-year OS (5-yr OS). Median follow-up was 59 months and median donor age was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01e0a6c9ffb1c0063ad047458ad9306
https://doi.org/10.1038/bmt.2013.14
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9
Outcome of allogeneic SCT in patients with chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy
Autor: Heinrich Lellek, Ulrike Bacher, Francis Ayuk, Nicolaus Kröger, Maximilian Christopeit, A A Oyekunle, Philippe Schafhausen, Thomas Stübig, Ingo Müller, Haefaa Alchalby, Mascha Binder, Tatjana Zabelina, Christine Wolschke, Axel R. Zander
Publikováno v: Annals of Hematology. 92:487-496
The introduction of tyrosine kinase inhibitors (TKIs) for chronic myeloid leukemia (CML) led to a dramatic change in the role of allogeneic stem cell transplantation (SCT) with a rapid decline in the number of patients receiving SCT in first chronic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7e8917e0b63579bc9cfd9949df2f26
https://doi.org/10.1007/s00277-012-1650-8
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10
Caspofungin plus posaconazole as salvage therapy of invasive fungal infections in immunocompromised patients
Autor: Dirk Waldenmaier, F Ayuk, Nicolaus Kröger, Heinrich Lellek, Axel R. Zander, Christine Wolschke, Joachim Dahlke
Publikováno v: Mycoses. 54:39-44
Invasive aspergillosis (IA) is a major cause of mortality in immunocompromised patients. Substantial improvements of treatment have been achieved by the introduction of new antifungal agents including azoles (e.g. posaconazole) and echinocandins (e.g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::683e8d41e8c0ef18ad7240717ed41509
https://doi.org/10.1111/j.1439-0507.2010.01985.x
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