Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Heinrich Hoffmann"'
Autor:
Henning Richter, Agnieszka Karol, Katja Nuss, Aymone Lenisa, Erika Bruellmann, Stella-Saphira Maudens, Heinrich Hoffmann, Brigitte von Rechenberg, Patrick R. Kircher
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-11 (2018)
Abstract Background Objective of this study is a feasibility-test comparing hock- and footpad-injection in rats with inoculated MatLyLu - adenocarcinoma tumor model. This study compares the development of an adenocarcinoma model (MatLyLu) in 12 Copen
Externí odkaz:
https://doaj.org/article/04d1e81c5f9b4934bddca8e47f5e0ee0
Autor:
Tomás Cervantes Rincón, Tania Kapoor, Jennifer R. Keeffe, Luca Simonelli, Hans-Heinrich Hoffmann, Marianna Agudelo, Andrea Jurado, Avery Peace, Yu E. Lee, Anna Gazumyan, Francesca Guidetti, Jasmine Cantergiani, Benedetta Cena, Filippo Bianchini, Elia Tamagnini, Simone G. Moro, Pavel Svoboda, Federico Costa, Mitermayer G. Reis, Albert I. Ko, Brian A. Fallon, Santiago Avila-Rios, Gustavo Reyes-Téran, Charles M. Rice, Michel C. Nussenzweig, Pamela J. Bjorkman, Daniel Ruzek, Luca Varani, Margaret R. MacDonald, Davide F. Robbiani
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114298- (2024)
Summary: Flaviviruses such as dengue virus (DENV), Zika virus (ZIKV), and yellow fever virus (YFV) are spread by mosquitoes and cause human disease and mortality in tropical areas. In contrast, Powassan virus (POWV), which causes severe neurologic il
Externí odkaz:
https://doaj.org/article/f2a8209fd48e4756be5a885d97b8d72f
Autor:
Natalia Cheshenko, Jeffrey B. Bonanno, Hans-Heinrich Hoffmann, Rohit K. Jangra, Kartik Chandran, Charles M. Rice, Steven C. Almo, Betsy C. Herold
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Abstract Herpes simplex virus (HSV) receptor engagement activates phospholipid scramblase triggering Akt translocation to the outer leaflet of the plasma membrane where its subsequent phosphorylation promotes viral entry. We hypothesize that this pre
Externí odkaz:
https://doaj.org/article/866ea4e637e248b58ed8a93146f4518b
Autor:
Sandra Nakandakari-Higa, Roham Parsa, Bernardo S. Reis, Renan V. H. de Carvalho, Luka Mesin, Hans-Heinrich Hoffmann, Juliana Bortolatto, Hiromi Muramatsu, Paulo. J. C. Lin, Angelina M. Bilate, Charles M. Rice, Norbert Pardi, Daniel Mucida, Gabriel D. Victora, Maria Cecilia C. Canesso
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Efficient mouse models to study SARS-CoV-2 infection are critical for the development and assessment of vaccines and therapeutic approaches to mitigate the current pandemic and prevent reemergence of COVID-19. While the first generation of mouse mode
Externí odkaz:
https://doaj.org/article/03a40c2ab38f4b908a732a3ff73ed920
Autor:
Natalia Cheshenko, Jeffrey B. Bonanno, Hans-Heinrich Hoffmann, Rohit K. Jangra, Kartik Chandran, Charles M. Rice, Steven C. Almo, Betsy C. Herold
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4d1acc8e80fd4e28a655751b6003208d
Autor:
Andrew M. Cheung, Elaine Z. Yip, Alison W. Ashbrook, Niluka Goonawardane, Corrine Quirk, Charles M. Rice, Margaret R. MacDonald, Hans-Heinrich Hoffmann
Publikováno v:
Vaccines, Vol 11, Iss 3, p 612 (2023)
Powassan virus (POWV) is an emerging tick-borne virus and cause of lethal encephalitis in humans. The lack of treatment or prevention strategies for POWV disease underscores the need for an effective POWV vaccine. Here, we took two independent approa
Externí odkaz:
https://doaj.org/article/c9877e3cacd14c7f98a32cc80b007701
Autor:
Frank J. Piscotta, Hans-Heinrich Hoffmann, Young Joo Choi, Gabriel I. Small, Alison W. Ashbrook, Bimal Koirala, Elizabeth A. Campbell, Seth A. Darst, Charles M. Rice, Sean F. Brady
Publikováno v:
mSphere, Vol 6, Iss 6 (2021)
ABSTRACT The COVID-19 pandemic has highlighted the need to identify additional antiviral small molecules to complement existing therapies. Although increasing evidence suggests that metabolites produced by the human microbiome have diverse biological
Externí odkaz:
https://doaj.org/article/b1866295b89c43e5b7d805cf12594bc0
Publikováno v:
Die Wirbelsäule. :110-122
Autor:
Jiwoon Park, Yuanyuan Zhao, Fan Zhang, Shaoyan Zhang, Andrew C. Kwong, Yujie Zhang, Hans-Heinrich Hoffmann, Leila Bushweller, Xin Wu, Alison W. Ashbrook, Branko Stefanovic, Shuyang Chen, Andrea D. Branch, Christopher E. Mason, Jae U. Jung, Charles M. Rice, Xianfang Wu
Publikováno v:
Journal of Hepatology. 78:45-56
A number of genetic polymorphisms have been associated with susceptibility to or protection against non-alcoholic fatty liver disease (NAFLD), but the underlying mechanisms remain unknown. Here, we focused on the rs738409 CG single nucleotide polymor
Autor:
Yiska Weisblum, Fabian Schmidt, Fengwen Zhang, Justin DaSilva, Daniel Poston, Julio CC Lorenzi, Frauke Muecksch, Magdalena Rutkowska, Hans-Heinrich Hoffmann, Eleftherios Michailidis, Christian Gaebler, Marianna Agudelo, Alice Cho, Zijun Wang, Anna Gazumyan, Melissa Cipolla, Larry Luchsinger, Christopher D Hillyer, Marina Caskey, Davide F Robbiani, Charles M Rice, Michel C Nussenzweig, Theodora Hatziioannou, Paul D Bieniasz
Publikováno v:
eLife, Vol 9 (2020)
Neutralizing antibodies elicited by prior infection or vaccination are likely to be key for future protection of individuals and populations against SARS-CoV-2. Moreover, passively administered antibodies are among the most promising therapeutic and
Externí odkaz:
https://doaj.org/article/79b3d5db1a464b1183d621d965b32b35