Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Heinrich Haas"'
Autor:
Clement E. Blanchet, Adam Round, Haydyn D. T. Mertens, Kartik Ayyer, Melissa Graewert, Salah Awel, Daniel Franke, Katerina Dörner, Saša Bajt, Richard Bean, Tânia F. Custódio, Raphael de Wijn, E. Juncheng, Alessandra Henkel, Andrey Gruzinov, Cy M. Jeffries, Yoonhee Kim, Henry Kirkwood, Marco Kloos, Juraj Knoška, Jayanath Koliyadu, Romain Letrun, Christian Löw, Jana Makroczyova, Abhishek Mall, Rob Meijers, Gisel Esperanza Pena Murillo, Dominik Oberthür, Ekaterina Round, Carolin Seuring, Marcin Sikorski, Patrik Vagovic, Joana Valerio, Tamme Wollweber, Yulong Zhuang, Joachim Schulz, Heinrich Haas, Henry N. Chapman, Adrian P. Mancuso, Dmitri Svergun
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Free-electron lasers (FEL) are revolutionizing X-ray-based structural biology methods. While protein crystallography is already routinely performed at FELs, Small Angle X-ray Scattering (SAXS) studies of biological macromolecules are not as
Externí odkaz:
https://doaj.org/article/bcf514c39af3436883cc2c8e5bf81aab
Autor:
Melissa A. Graewert, Christoph Wilhelmy, Tijana Bacic, Jens Schumacher, Clement Blanchet, Florian Meier, Roland Drexel, Roland Welz, Bastian Kolb, Kim Bartels, Thomas Nawroth, Thorsten Klein, Dmitri Svergun, Peter Langguth, Heinrich Haas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract We present a generically applicable approach to determine an extensive set of size-dependent critical quality attributes inside nanoparticulate pharmaceutical products. By coupling asymmetrical-flow field-flow fractionation (AF4) measurement
Externí odkaz:
https://doaj.org/article/6cbcb21a01a44fe191b433cb76ef64fd
Autor:
Christoph Wilhelmy, Isabell Sofia Keil, Lukas Uebbing, Martin A. Schroer, Daniel Franke, Thomas Nawroth, Matthias Barz, Ugur Sahin, Heinrich Haas, Mustafa Diken, Peter Langguth
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2068 (2023)
Lipid nanoparticles (LNPs) have gained great attention as carriers for mRNA-based therapeutics, finding applications in various indications, extending beyond their recent use in vaccines for infectious diseases. However, many aspects of LNP structure
Externí odkaz:
https://doaj.org/article/0661639078014c83ae3f7dc08cc22219
Autor:
Yoann Aldon, Paul F. McKay, Jorge Moreno Herrero, Annette B. Vogel, Réka Lévai, Pauline Maisonnasse, Nathalie Dereuddre-Bosquet, Heinrich Haas, Katalin Fábián, Roger Le Grand, Ugur Sahin, Robin J. Shattock
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 483-493 (2021)
Self-amplifying mRNA (saRNA) represents a promising platform for nucleic acid delivery of vaccine immunogens. Unlike plasmid DNA, saRNA does not require entry into the nucleus of target cells for expression, having the capacity to drive higher protei
Externí odkaz:
https://doaj.org/article/29be14ddbad34f018d2ece57d78aef2f
Autor:
Matthias Miederer, Stefanie Pektor, Isabelle Miederer, Nicole Bausbacher, Isabell Sofia Keil, Hossam Hefesha, Heinrich Haas, Ugur Sahin, Mustafa Diken
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Background RNA-based vaccination strategies tailoring immune response to specific reactions have become an important pillar for a broad range of applications. Recently, the use of lipid-based nanoparticles opened the possibility to deliver R
Externí odkaz:
https://doaj.org/article/7a4f47015d744cba8fd73de21cfb453d
Autor:
Maximilian E. A. Schäfer, Florian Keller, Jens Schumacher, Heinrich Haas, Fulvia Vascotto, Ugur Sahin, Mathias Hafner, Rüdiger Rudolf
Publikováno v:
Cells, Vol 11, Iss 6, p 1026 (2022)
Cancer therapy is an emergent application for mRNA therapeutics. While in tumor immunotherapy, mRNA encoding for tumor-associated antigens is delivered to antigen-presenting cells in spleen and lymph nodes, other therapeutic options benefit from imme
Externí odkaz:
https://doaj.org/article/13bfef6b877d45cea48456279596b567
Autor:
Christian D. Siewert, Heinrich Haas, Vera Cornet, Sara S. Nogueira, Thomas Nawroth, Lukas Uebbing, Antje Ziller, Jozef Al-Gousous, Aurel Radulescu, Martin A. Schroer, Clement E. Blanchet, Dmitri I. Svergun, Markus P. Radsak, Ugur Sahin, Peter Langguth
Publikováno v:
Cells, Vol 9, Iss 9, p 2034 (2020)
Hybrid nanoparticles from lipidic and polymeric components were assembled to serve as vehicles for the transfection of messenger RNA (mRNA) using different portions of the cationic lipid DOTAP (1,2-Dioleoyl-3-trimethylammonium-propane) and the cation
Externí odkaz:
https://doaj.org/article/ccd7af2a8e2e49719ca289339c9736b3
Autor:
Hermann Heinrich Haas
Der verhaltensbedingten Kündigung des Arbeitsverhältnisses kommt in der arbeitsrechtlichen Praxis erhebliche Bedeutung zu. Kaum ein arbeitsrechtlicher Tatbestand hängt so sehr von den Umständen des Einzelfalls und damit der richterlichen Würdigu
Autor:
Valentina Andretto, Mathieu Repellin, Marine Pujol, Eyad Almouazen, Jacqueline Sidi-Boumedine, Thierry Granjon, Heyang Zhang, Katrien Remaut, Lars Petter Jordheim, Stéphanie Briançon, Isabell Sofia Keil, Fulvia Vascotto, Kerstin C. Walzer, Ugur Sahin, Heinrich Haas, David Kryza, Giovanna Lollo
Publikováno v:
Journal of Controlled Release. 353:1037-1049
mRNA based infectious disease vaccines have opened the venue for development of novel nucleic acids-based therapeutics. For all mRNA therapeutics dedicated delivery systems are required, where different functionalities and targeting abilities need to
Autor:
Hermann Bauer, Heinrich Haas
Publikováno v:
Zeitschrift des Historischen Vereins für das Württembergische Franken. 3:81-93
Haas, Heinrich: Der Rangau, seine Grafen und ältere Rechts-, Orts- und Landesgeschichte mit neuen Forschungen über die Abstammung der Burggrafen von Nürnberg, Erlangen: Palm'sche Verlagsbuchhandlung, 1853. XII, 256 S.