Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Heinrich Betz"'
Autor:
Seungjoon Kim, Mooseok Kang, Dongseok Park, Ae-Ree Lee, Heinrich Betz, Jaewon Ko, Iksoo Chang, Ji Won Um
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102037- (2021)
Summary: Gephyrin is critical for the structure, function, and plasticity of inhibitory synapses. Gephyrin mutations have been linked to various neurological disorders; however, systematic analyses of the functional consequences of these mutations ar
Externí odkaz:
https://doaj.org/article/6832200f58e14551b92e9bc5d33a33e3
Autor:
Horst Andreas Obenhaus, Andrei Rozov, Ilaria Bertocchi, Wannan Tang, Joachim Kirsch, Heinrich Betz, Rolf Sprengel
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
The causal interrogation of neuronal networks involved in specific behaviors requires the spatially and temporally controlled modulation of neuronal activity. For long-term manipulation of neuronal activity, chemogenetic tools provide a reasonable al
Externí odkaz:
https://doaj.org/article/ca06de41769b45b4b845982f5a72067a
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 3 (2010)
Glycine has diverse functions within the mammalian central nervous system. It inhibits postsynaptic neurons via strychnine-sensitive glycine receptors (GlyRs) and enhances neuronal excitation through co-activation of N-methyl-D-aspartate (NMDA) recep
Externí odkaz:
https://doaj.org/article/c8b8b7d444b8428e869f9c109bf47b78
Autor:
Mooseok Kang, Jaewon Ko, Ae-Ree Lee, Dongseok Park, Iksoo Chang, Heinrich Betz, Ji Won Um, Seungjoon Kim
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102037-(2021)
iScience
iScience
Summary Gephyrin is critical for the structure, function, and plasticity of inhibitory synapses. Gephyrin mutations have been linked to various neurological disorders; however, systematic analyses of the functional consequences of these mutations are
Autor:
Cord-Michael Becker, Christian Neubert, Julia Dlugaiczyk, Dario Campanelli, Heinrich Betz, Bernhard Schick, Lukas Rüttiger, Dietmar Hecker, Marlies Knipper, Stefanie Buerbank
Publikováno v:
Hearing Research
Inhibitory glycine receptors containing the α3 subunit (GlyRα3) regulate sensory information processing in the CNS and retina. In previous work, we demonstrated the presence of postsynaptic GlyRα3 immunoreactivity at efferent synapses of the media
Publikováno v:
Neuropharmacology
N-methyl-d-aspartate (NMDA) receptors composed of glycine-binding GluN1 and GluN3 subunits function as excitatory glycine receptors that respond to agonist application only with a very low efficacy. Binding of glycine to the high-affinity GluN3 subun
We have recently shown that the abundance of the renal sodium (Na)/inorganic phosphate (Pi) cotransporter NaPi-IIa is increased in the absence of the GABA(A) receptor-associated protein (GABARAP). Accordingly, GABARAP-deficient mice have a reduced ur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc6d1b05bd56567411c99242b0190c6
http://doc.rero.ch/record/310831/files/424_2010_Article_832.pdf
http://doc.rero.ch/record/310831/files/424_2010_Article_832.pdf
Autor:
Daniel C. Lowes, Michael C. Salling, Yuri A. Blednov, R. Adron Harris, Naomi N. Odean, Cyndel Carreau-Vollmer, Lindsay M. McCracken, Neil L. Harrison, Heinrich Betz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Neuronal inhibition can occur via synaptic mechanisms or through tonic activation of extrasynaptic receptors. In spinal cord, glycine mediates synaptic inhibition through the activation of heteromeric glycine receptors (GlyRs) composed primarily of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de80099f27eed03f8609ee94431bcd56
https://hdl.handle.net/21.11116/0000-0000-756A-621.11116/0000-0000-756B-521.11116/0000-0000-7568-8
https://hdl.handle.net/21.11116/0000-0000-756A-621.11116/0000-0000-756B-521.11116/0000-0000-7568-8
Autor:
Juan Carlos Gómez-Esteban, Helmut Kettenmann, Edmond H. Fischer, Serafim Rodrigues, John P. Adelman, Detlev Ganten, Sherif F. El-Khamisy, Shoji Komai, Agnès Gruart, Ashraf H. Badawi, S. Ather Enam, Atta-ur Rahman, Yasunori Hayashi, Andreas Draguhn, José L. Zugaza, Mohamed Jaber, Mustafa al'Absi, Mohammed Akaaboune, Jimena Baleriola, Hollis T. Cline, Thomas Lissek, Luis Martinez-Millan, Tiago F. Outeiro, Nouria Lakhdar Ghazal, Nikhat Ahmed Siddiqui, John E. Dowling, Erwin Neher, Karoly Nikolich, Joshua R. Sanes, Paul Young, Roger Guillemin, Ahmed A. Moustafa, Pedro Ramos-Cabrer, John F. Disterhoft, Craig Weiss, Michelle M. Adams, Mouna Maroun, José M. Delgado-García, Mario Treviño, Cathy C. Chang, Nasser H. Zawia, Tansu Celikel, Anwar Nasim, Ilaria Bertocchi, Carlos Belmonte, Kellie Dean, Andreas T. Schaefer, Hilmar Bading, Donald W. Pfaff, Bruno Poucet, José A. Esteban, Nils Brose, Reinhardt Jahn, Basim M. Uthman, Menahem Segal, Juan M. Encinas, Heinrich Betz, Ta Yuan Chang, Greg J. Stuart, Matthew E. Larkum, Patrizia Campolongo, Paolo Bonifazi, Larry J. Young, Olga Peñagarikano, Mathieu Desroches, Ofer Yizhar, Valery Grinevich, Merel Kindt, Abdeljabbar El Manira, J. Craig Venter, Richard J. Roberts, Hermona Soreq, Kathleen E. Cullen, Idan Segev, Saad Shafqat, Alexei Verkhratsky, Tobias Bonhoeffer, Adnan Abdul Jabbar, Mickey London, Torsten N. Wiesel, Jan Tønnesen, Asier Erramuzpe, Georg Köhr, Mohamed Kabbaj, Juan Carlos Arango-Lasprilla, Paul Greengard, Ali Rashidy-Pour, Beat Lutz, Albert Gidon, Abdul Mannan Baig, Michael Häusser, Ami Citri, Fazal Manzoor Arain, Mazahir T. Hasan, Iñigo Gabilondo, Olaf Blanke, Izumi Fukunaga, Emre Yaksi, Lucy M. Palmer, Ahmad R. Hariri, Bernd Kuhn, Isabel Fariñas, Huda Akil, Harm J. Krugers, Philipp Boehm-Sturm, Klaus-Armin Nave, Essam M. Janahi, Thomas C. Südhof, Ehud Ahissar, Colin Blakemore, Jesús Avila, Deniz Atasoy, Bassem A. Hassan, Shira Knafo, Eduardo Soriano-García, Isabel Pérez-Otaño, James L. McGaugh, Natasha K. Hussain, Rainer Spanagel, Carlos Matute, Rolf Sprengel, Jesus M. Cortes
Publikováno v:
Neuron
Neuron, 96, 730-735
Neuron, 96, 4, pp. 730-735
Neuron, 96, 730-735
Neuron, 96, 4, pp. 730-735
WOS: 000415310800007 PubMed ID: 29144972 Science is ideally suited to connect people from different cultures and thereby foster mutual understanding. To promote international life science collaboration, we have launched "The Science Bridge'' initiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4a659b032167722fdc09149e38fcb8
http://hdl.handle.net/2318/1662890
http://hdl.handle.net/2318/1662890
Publikováno v:
Journal of Biological Chemistry. 289:11396-11409
Glycine receptors (GlyRs) mediate inhibitory neurotransmission in spinal cord and brainstem. They are clustered at inhibitory postsynapses via a tight interaction of their β subunits (GlyRβ) with the scaffolding protein gephyrin. In an attempt to i