Výsledky vyhledávání - "Heinrich, Schrewe"

Akademický článek

Vasorin-deficient mice display disturbed vitamin D and mineral homeostasis in combination with a low bone mass phenotype

Autor: Marco Eijken, A. Michaela Krautzberger, Manuela Scholze-Wittler, Bianca Boers-Sijmons, Marijke Koedam, Barbara Kosiol, Heinrich Schrewe, Johannes P. van Leeuwen, Bram C. van der Eerden

Publikováno v: Bone Reports, Vol 22, Iss , Pp 101792- (2024)

Vasorin (Vasn) is a pleiotropic molecule involved in various physiological and pathological conditions, including cancer. Vasn has also been detected in bone cells of developing skeletal tissues but no function for Vasn in bone metabolism has been im

Externí odkaz: https://doaj.org/article/fb30148d48904876972ed4fe2a7c03eb

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Akademický článek

Autor: Jürgen Stumm, Pedro Vallecillo-García, Sophie Vom Hofe-Schneider, David Ollitrault, Heinrich Schrewe, Aris N. Economides, Giovanna Marazzi, David A. Sassoon, Sigmar Stricker

Publikováno v: Stem Cell Research, Vol 32, Iss , Pp 8-16 (2018)

Fibro-adipogenic progenitors (FAPs) are resident mesenchymal progenitors in adult skeletal muscle that support muscle repair, but also give rise to fibrous and adipose infiltration in response to disease and chronic injury. FAPs are identified using

Externí odkaz: https://doaj.org/article/998eb6efcebd4550a4742b5099f18bf3

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Akademický článek

From Vascular Smooth Muscle Cells to Folliculogenesis: What About Vasorin?

Autor: Anne-Laure Bonnet, Catherine Chaussain, Isabelle Broutin, Gaël Y. Rochefort, Heinrich Schrewe, Céline Gaucher

Publikováno v: Frontiers in Medicine, Vol 5 (2018)

First described in 1988, vasorin (VASN) is a transmembrane glycoprotein expressed during early mouse development, and with a less extent, in various organs and tissues (e.g., kidney, aorta, and brain) postnatally. Vasn KO mice die after 3 weeks of li

Externí odkaz: https://doaj.org/article/b41eea45aaf84f48a3f4585f1bba24cf

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Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis

Autor: Teng-Wei Huang, Amrita A. Iyer, Melissa M. McGovern, Jeanne M. Manalo, Kevin K. Ohlemiller, Navish A. Bosquez Huerta, Heinrich Schrewe, Benjamin Deneen, Junsung Woo, Andrew K. Groves, Fredrick A. Pereira

Publikováno v: J Neurosci
The Journal of Neuroscience

Mediator protein complex subunit 12 (Med12) is a core component of the basal transcriptional apparatus and plays a critical role in the development of many tissues. Mutations in Med12 are associated with X-linked intellectual disability syndromes and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00e34f75e25fc41192fee652cc170cf
https://doi.org/10.1523/jneurosci.0070-21.2021

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Akademický článek

The Phospholipase D2 Knock Out Mouse Has Ectopic Purkinje Cells and Suffers from Early Adult-Onset Anosmia.

Autor: Matthieu M Vermeren, Qifeng Zhang, Elizabeth Smethurst, Anne Segonds-Pichon, Heinrich Schrewe, Michael J O Wakelam

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0162814 (2016)

Phospholipase D2 (PLD2) is an enzyme that produces phosphatidic acid (PA), a lipid messenger molecule involved in a number of cellular events including, through its membrane curvature properties, endocytosis. The PLD2 knock out (PLD2KO) mouse has bee

Externí odkaz: https://doaj.org/article/08c6d72cd8164d30b2a4638761b5cd4a

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Vasorin Plays a Critical Role in Vascular Smooth Muscle Cells and Arterial Functions

Autor: Loïc Louvet, Gaëlle Lenglet, A. Michaela Krautzberger, Romuald Mentaverri, Frédéric Hague, Clara Kowalewski, Nassim Mahtal, Julie Lesieur, Anne‐Laure Bonnet, Caroline Andrique, Céline Gaucher, Cathy Gomila, Heinrich Schrewe, Pierre‐Louis Tharaux, Said Kamel, Catherine Chaussain, Isabelle Six

Publikováno v: Journal of Cellular Physiology
Journal of Cellular Physiology, 2022, ⟨10.1002/jcp.30838⟩

International audience; Within the cardiovascular system, the protein vasorin (Vasn) is predominantly expressed by vascular smooth muscle cells (VSMCs) in the coronary arteries and the aorta. Vasn knockout (Vasn(-/-) ) mice die within 3 weeks of birt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127ad9bb4d4cd3e79beff4793a7792cb
https://u-picardie.hal.science/hal-03740510

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Akademický článek

Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia.

Autor: Farhat L Khanim, Rachel E Hayden, Jane Birtwistle, Alessia Lodi, Stefano Tiziani, Nicholas J Davies, Jon P Ride, Mark R Viant, Ulrich L Gunther, Joanne C Mountford, Heinrich Schrewe, Richard M Green, Jim A Murray, Mark T Drayson, Chris M Bunce

Publikováno v: PLoS ONE, Vol 4, Iss 12, p e8147 (2009)

BackgroundThe majority of acute myeloid leukaemia (AML) patients are over sixty years of age. With current treatment regimens, survival rates amongst these, and also those younger patients who relapse, remain dismal and novel therapies are urgently r

Externí odkaz: https://doaj.org/article/9636c763c1a443abb133d3874ed80303

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Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency

Publikováno v: Journal of Inherited Metabolic Disease
Journal of inherited metabolic disease 42(5), 839-849 (2019). doi:10.1002/jimd.12105
J. Inherit. Metab. Dis. 42, 839-849 (2019)

Triosephosphate isomerase (TPI) deficiency is a fatal genetic disorder characterized by hemolytic anemia and neurological dysfunction. Although the enzyme defect in TPI was discovered in the 1960s, the exact etiology of the disease is still debated.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc9b7daee234fa033a69f5666742a4f
https://mediatum.ub.tum.de/doc/1539484/document.pdf

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Autor: Sigmar Stricker, David Sassoon, Sophie vom Hofe-Schneider, Pedro Vallecillo Garcia, David Ollitrault, Jürgen Stumm, Aris N. Economides, Heinrich Schrewe, Giovanna Marazzi

Publikováno v: Stem Cell Research
Stem Cell Research, Elsevier, 2018, 32, pp.8-16. ⟨10.1016/j.scr.2018.08.010⟩
Stem Cell Research, Vol 32, Iss, Pp 8-16 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b92da3c92aa7bf01aaebb28bbe4ee30
https://hal.sorbonne-universite.fr/hal-01908913

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