Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Heinke Schnabel"'
Autor:
Ralf Schnabel, Michael O. Hengartner, Richard Feichtinger, Juan Cabello, Heinke Schnabel, Kelvin K. L. Wong, Jason M. Kinchen, Doris Klingele
Publikováno v:
Nature. 434:93-99
The removal of apoptotic cells is essential for the physiological well being of the organism. In Caenorhabditis elegans, two conserved, partially redundant genetic pathways regulate this process. In the first pathway, the proteins CED-2, CED-5 and CE
Autor:
Ivica Krascenicova, Michael Glotzer, Alper Romano, Heinke Schnabel, Annika Guse, Ralf Schnabel
Publikováno v:
Journal of Cell Biology. 161:229-236
The Aurora B kinase complex is a critical regulator of chromosome segregation and cytokinesis. In Caenorhabditis elegans, AIR-2 (Aurora B) function requires ICP-1 (Incenp) and BIR-1 (Survivin). In various systems, Aurora B binds to orthologues of the
Autor:
Alper Romano, Ralf Schnabel, Heinke Schnabel, Pierre Gönczy, Michael Glotzer, Danielle R. Hamill, Verena Jantsch-Plunger, Anthony A. Hyman
Publikováno v:
Journal of Cell Biology. 149:1391-1404
During cytokinesis of animal cells, the mitotic spindle plays at least two roles. Initially, the spindle positions the contractile ring. Subsequently, the central spindle, which is composed of microtubule bundles that form during anaphase, promotes a
Publikováno v:
The Journal of Cell Biology
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To identify novel components required for cell division processes in complex eukaryotes, we have undertaken an extensive mutational analysis in the one cell stage Caenorhabditis elegans embryo. The large size and optical properties of this cell permi
Autor:
Ralf Schnabel, Heinke Schnabel
Publikováno v:
Development. 108:107-119
The early somatic blastomeres founding the tissues in the C. elegans embryo are derived in a stem-cell-like lineage from the P cells. We have isolated maternal effect lethal mutations defining the gene cib-1 in which the P cells, Pi-P3, skip a cell c
Autor:
Karine Baumer, Ralf Schnabel, Richard Feichtinger, Heinke Schnabel, Marie Delattre, Jeannine Bamat, Khursheed A. Wani, Sebastian A. Leidel, Pierre Gönczy
Publikováno v:
Nature cell biology. 6(7)
Centrosomes, the major microtubule-organizing centres (MTOCs) of animal cells, are comprised of a pair of centrioles surrounded by pericentriolar material (PCM). Early in the cell cycle, there is a single centrosome, which duplicates during S-phase t
Autor:
Alper, Romano, Annika, Guse, Ivica, Krascenicova, Heinke, Schnabel, Ralf, Schnabel, Michael, Glotzer
Publikováno v:
The Journal of Cell Biology
The Aurora B kinase complex is a critical regulator of chromosome segregation and cytokinesis. In Caenorhabditis elegans, AIR-2 (Aurora B) function requires ICP-1 (Incenp) and BIR-1 (Survivin). In various systems, Aurora B binds to orthologues of the
Publikováno v:
Journal of cell science. 115(Pt 11)
In the early Caenorhabditis elegans embryo, establishment of cell polarity and cytokinesis are both dependent upon reorganization of the actin cytoskeleton. Mutations in the cyk-3 gene cause maternal effect embryonic lethality. Embryos produced by ho
Publikováno v:
Gene. 229(1-2)
A novel method to transform the nematode Caenorhabditis elegans is described. DNA coprecipitated with gold particles is shot at worms by means of a helium beam. Transformed worms are either identified by a dominant visible marker or selected by a con
Autor:
Ian A. Hope, Richard Feichtinger, Heinke Schnabel, Laurent Molin, Ralf Schnabel, Titus Kaletta
Publikováno v:
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In the early Caenorhabditis elegans embryo five somatic founder cells are born during the first cleavages. The first of these founder cells, named AB, gives rise to 389 of the 558 nuclei present in the hatching larva. Very few genes directly involved