Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Heini Ilves"'
Autor:
Pradheep Chhalliyil, Heini Ilves, Sergei A. Kazakov, Stephanie J. Howard, Brian H. Johnston, John Fagan
Publikováno v:
Foods, Vol 11, Iss 4, p 585 (2022)
The stated objective of the paper was to provide regulatory laboratories and industry laboratories a complete, legally robust method for the quantitative detection of SU canola [...]
Externí odkaz:
https://doaj.org/article/0bfd7f3b9f894534be594400c595820e
Autor:
Pradheep Chhalliyil, Heini Ilves, Sergei A. Kazakov, Stephanie J. Howard, Brian H. Johnston, John Fagan
Publikováno v:
Foods, Vol 9, Iss 9, p 1245 (2020)
Discussion regarding the regulatory status of genome-edited crops has focused on precision of editing and on doubts regarding the feasibility of analytical monitoring compliant with existing GMO regulations. Effective detection methods are important,
Externí odkaz:
https://doaj.org/article/2be0ed3e170d4ca396d79c427328cd98
Autor:
Janos A. Barrera, Nina Kosaric, Paula T. Hammond, Sumedha D. Jayasena, Karl Engel, Zachary A. Stern-Buchbinder, Clark A. Bonham, Artem A. Trotsyuk, Kenneth J. Mandell, Geoffrey C. Gurtner, Heini Ilves, Melanie Rodrigues, Brian H. Johnston, Jonathan Mansbridge, Anne Dallas, Aleksandr J. White
Publikováno v:
Tissue Engineering Part A. 25:44-54
In diabetes-associated chronic wounds, the normal response to hypoxia is impaired and many cellular processes involved in wound healing are hindered. Central to the hypoxia response is hypoxia-inducible factor-1α (HIF-1α), which activates multiple
Autor:
Anne Dallas, Heini Ilves, Joshua Shorenstein, Adam Judge, Ryan Spitler, Christopher Contag, Suet Ping Wong, Richard P Harbottle, Ian MacLachlan, Brian H Johnston
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
We previously identified short synthetic shRNAs (sshRNAs) that target a conserved hepatitis C virus (HCV) sequence within the internal ribosome entry site (IRES) of HCV and potently inhibit HCV IRES-linked gene expression. To assess in vivo liver del
Externí odkaz:
https://doaj.org/article/cc3ef4ed86644013a09e86d0ed1bed5e
Autor:
Sergei A. Kazakov, John Fagan, Brian H. Johnston, Stephanie J Howard, Heini Ilves, Pradheep Chhalliyil
Publikováno v:
Foods, Vol 9, Iss 1245, p 1245 (2020)
Foods
Foods; Volume 9; Issue 9; Pages: 1245
Foods
Foods; Volume 9; Issue 9; Pages: 1245
Discussion regarding the regulatory status of genome-edited crops has focused on precision of editing and on doubts regarding the feasibility of analytical monitoring compliant with existing GMO regulations. Effective detection methods are important,
Autor:
Sergei A. Kazakov, Pavan Kumar, Michael T. McManus, Anne Dallas, Mark A. Behlke, Qing Ge, Joshua Shorenstein, Trinna L. Cuellar, Heini Ilves, Brian H. Johnston
Publikováno v:
Nucleic Acids Research
Small hairpin RNAs (shRNAs) having duplex lengths of 25-29 bp are normally processed by Dicer into short interfering RNAs (siRNAs) before incorporation into the RNA-induced silencing complex (RISC). However, shRNAs of ≤ 19 bp [short shRNAs (sshRNAs
Autor:
Pavan Kumar, Heini Ilves, Joshua Shorenstein, Qing Ge, Sergei A. Kazakov, Anne Dallas, Brian H. Johnston
Publikováno v:
RNA. 16:106-117
Small hairpin RNAs (shRNAs) are widely used in RNAi studies and typically consist of a stem of 19–29 base pairs (bp), a loop of at least 4 nucleotides (nt), and a dinucleotide overhang at the 3′ end. Compared with shRNAs with 21–29 bp stems, we
Publikováno v:
RNA. 16:118-130
Small hairpin RNAs (shRNAs) with 19-base-pair, or shorter, stems (short shRNAs [sshRNAs]) have been found to constitute a class whose mechanism of action appears to be distinct from that of small interfering RNAs (siRNAs) or longer shRNAs. These sshR
Autor:
Christopher H. Contag, Qian Wang, Emilio Gonzalez-Gonzalez, Robyn P. Hickerson, Devin Leake, Heini Ilves, Roger L. Kaspar, Brian H. Johnston, Alexander V. Vlassov
Publikováno v:
Oligonucleotides. 18:345-354
RNA interference offers enormous potential to develop therapeutic agents for a variety of diseases. To assess the stability of siRNAs under conditions relevant to clinical use with particular emphasis on topical delivery considerations, a study of th
Autor:
Kevin O. Kisich, Tai Chih Kuo, Roger L. Kaspar, Anne Dallas, Brian H. Johnston, Alexander V. Vlassov, Heini Ilves, Sergei A. Kazakov, Svetlana V. Balatskaya
Publikováno v:
Nucleic Acids Research
We have developed a novel class of antisense agents, RNA Lassos, which are capable of binding to and circularizing around complementary target RNAs. The RNA Lasso consists of a fixed sequence derived from the hairpin ribozyme and an antisense segment