Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Heinfried H Radeke"'
Autor:
Kathrin Pfarr, Corina Danciu, Olga Arlt, Christina Neske, Cristina Dehelean, Josef M Pfeilschifter, Heinfried H Radeke
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118802 (2015)
Conventional cytostatic cancer treatments rarely result in the complete eradication of tumor cells. Therefore, new therapeutic strategies focus on antagonizing the immunosuppressive activity of established tumors. In particular, recent studies of ant
Externí odkaz:
https://doaj.org/article/54999881714c43ad931ea9bc3d263370
Autor:
Lukasz Japtok, Katrin Schaper, Wolfgang Bäumer, Heinfried H Radeke, Se Kyoo Jeong, Burkhard Kleuser
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49427 (2012)
Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs. Recently, it has been indicated
Externí odkaz:
https://doaj.org/article/d84a7388d2544e6fbabb56379a2b57a4
Autor:
Verena Bihrer, Oliver Waidmann, Mireen Friedrich-Rust, Nicole Forestier, Simone Susser, Jörg Haupenthal, Martin Welker, Ying Shi, Jan Peveling-Oberhag, Andreas Polta, Michael von Wagner, Heinfried H Radeke, Christoph Sarrazin, Jörg Trojan, Stefan Zeuzem, Bernd Kronenberger, Albrecht Piiper
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26971 (2011)
BACKGROUND: MicroRNA-21 (miR-21) is up-regulated in tumor tissue of patients with malignant diseases, including hepatocellular carcinoma (HCC). Elevated concentrations of miR-21 have also been found in sera or plasma from patients with malignancies,
Externí odkaz:
https://doaj.org/article/65901544414a4cefa9867b93cc8973e9
Autor:
Larisa Bora, Tobias Burkard, Martina Herrero San Juan, Heinfried H. Radeke, Ana Maria Muț, Lavinia Lia Vlaia, Ioana Zinuca Magyari-Pavel, Zorița Diaconeasa, Sonia Socaci, Florin Borcan, Brigitta Kis, Delia Muntean, Cristina Adriana Dehelean, Corina Danciu
Publikováno v:
Pharmaceutics; Volume 14; Issue 11; Pages: 2413
This study presents phytochemical characterization and biological evaluation of Origanum vulgare L. essential oil (OEO) formulated as polymeric micelles drug delivery systems as a possible non-invasive approach for the management of skin tags. GC-MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e29bc97673943767db4341831fd65f4
Autor:
Tobias, Burkard, Martina, Herrero San Juan, Caroline, Dreis, Anastasiia, Kiprina, Dmitry, Namgaladze, Kai, Siebenbrodt, Sebastian, Luger, Christian, Foerch, Josef M, Pfeilschifter, Andreas, Weigert, Heinfried H, Radeke
Publikováno v:
Clinical and translational medicineREFERENCES. 12(12)
Cytotoxic T lymphocytes take on a leading role in many immune-related diseases. They function as key effector immune cells fighting cancer cells, but they are also considerably involved in autoimmune diseases. Common to both situations, CD8We used an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c34301f5d17229db6d8e1e1c7758495
https://pubmed.ncbi.nlm.nih.gov/36504430
https://pubmed.ncbi.nlm.nih.gov/36504430
Autor:
Katrin G. Schmidt, Martina Herrero San Juan, Sandra Trautmann, Lucija Berninger, Anja Schwiebs, Florian M. Ottenlinger, Dominique Thomas, Frank Zaucke, Josef M. Pfeilschifter, Heinfried H. Radeke
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Systemic sclerosis (SSc) is a rare multi-organ autoimmune disease characterized by progressive skin fibrosis. Inflammation, type 2 immunity, and fibrogenic processes are involved in disease development and may be affected by sphingolipids. However, d
Externí odkaz:
https://doaj.org/article/e8da4c3c7a9a49eabe1d5fe6bd9e0ca8
Autor:
Heinfried H. Radeke, Wajiha Farha Faqar-Uz-Zaman, Dominique Thomas, Josef Pfeilschifter, Katrin G. Schmidt, Anja Schwiebs
Publikováno v:
Lipids. 56:155-166
Sphingosine-1-phosphate lyase 1 (S1P lyase or SGPL1) is an essential sphingosine-1-phosphate-degrading enzyme. Its manipulation favors onset and progression of colorectal cancer and others in vivo. Thus, SGPL1 is an important modulator of cancer init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381dd3bf2a640b1913418d8248ad1675
https://doi.org/10.1002/lipd.12282
https://doi.org/10.1002/lipd.12282
Nanoplastics affect the inflammatory cytokine release by primary human monocytes and dendritic cells
Autor:
Annkatrin Weber, Anja Schwiebs, Helene Solhaug, Jørgen Stenvik, Asbjørn M. Nilsen, Martin Wagner, Borna Relja, Heinfried H. Radeke
Publikováno v:
Environment International
So far, the human health impacts of nano- and microplastics are poorly understood. Thus, we investigated whether nanoplastics exposure induces inflammatory processes in primary human monocytes and monocyte-derived dendritic cells. We exposed these ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384289d6abddfa260e181688b6f04b84
https://hdl.handle.net/11250/3048155
https://hdl.handle.net/11250/3048155
Autor:
Tobias Burkard, Caroline Dreis, Martina Herrero San Juan, Meik Huhn, Andreas Weigert, Josef M. Pfeilschifter, Heinfried H. Radeke
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment. Infiltrating regulatory T lymphocytes contribute to this immunosuppression by inhibiting prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2c60cdb997b41bb8946a536042a68fc5
http://europepmc.org/articles/PMC8421764
http://europepmc.org/articles/PMC8421764
Autor:
Brigitta Kis, Ioana Zinuca Pavel, Stefana Avram, Elena Alina Moaca, Martina Herrero San Juan, Anja Schwiebs, Heinfried H. Radeke, Delia Muntean, Zorita Diaconeasa, Daliana Minda, Camelia Oprean, Florina Bojin, Cristina Adriana Dehelean, Codruta Soica, Corina Danciu
Publikováno v:
BMC complementary medicine and therapies. 22(1)
Purpose The aim of this study was to evaluate the antioxidant potential, antimicrobial activity, the in vitro anticancer effect (tested on MCF-7 breast cancer cell line), as well as the antiangiogenic and immunomodulatory potential of Populus nigra L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ace0ab75175c0c70ebe80115d6d7d7
https://pubmed.ncbi.nlm.nih.gov/35296309
https://pubmed.ncbi.nlm.nih.gov/35296309