Zobrazeno 1 - 10
of 402
pro vyhledávání: '"Heinfried H Radeke"'
Autor:
Brigitta Kis, Ioana Zinuca Pavel, Stefana Avram, Elena Alina Moaca, Martina Herrero San Juan, Anja Schwiebs, Heinfried H. Radeke, Delia Muntean, Zorita Diaconeasa, Daliana Minda, Camelia Oprean, Florina Bojin, Cristina Adriana Dehelean, Codruta Soica, Corina Danciu
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-24 (2022)
Abstract Purpose The aim of this study was to evaluate the antioxidant potential, antimicrobial activity, the in vitro anticancer effect (tested on MCF-7 breast cancer cell line), as well as the antiangiogenic and immunomodulatory potential of Populu
Externí odkaz:
https://doaj.org/article/d9667e9c3ac9424299c1658506241a44
Autor:
Tobias Burkard, Martina Herrero San Juan, Caroline Dreis, Anastasiia Kiprina, Dmitry Namgaladze, Kai Siebenbrodt, Sebastian Luger, Christian Foerch, Josef M. Pfeilschifter, Andreas Weigert, Heinfried H. Radeke
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 12, Pp n/a-n/a (2022)
Abstract Background Cytotoxic T lymphocytes take on a leading role in many immune‐related diseases. They function as key effector immune cells fighting cancer cells, but they are also considerably involved in autoimmune diseases. Common to both sit
Externí odkaz:
https://doaj.org/article/7eed57691bec422787e31c4226ec75ee
Nanoplastics affect the inflammatory cytokine release by primary human monocytes and dendritic cells
Autor:
Annkatrin Weber, Anja Schwiebs, Helene Solhaug, Jørgen Stenvik, Asbjørn M. Nilsen, Martin Wagner, Borna Relja, Heinfried H. Radeke
Publikováno v:
Environment International, Vol 163, Iss , Pp 107173- (2022)
So far, the human health impacts of nano- and microplastics are poorly understood. Thus, we investigated whether nanoplastics exposure induces inflammatory processes in primary human monocytes and monocyte-derived dendritic cells. We exposed these ce
Externí odkaz:
https://doaj.org/article/c8259076b6944811b24cdcfef9f7c653
Autor:
Heinfried H. Radeke, Jürgen Stein, Gert Van Assche, Gerhard Rogler, Peter L. Lakatos, Florian Muellershausen, Pierre Moulin, Philip Jarvis, Laurence Colin, Peter Gergely, Wolfgang Kruis
Publikováno v:
Inflammatory Intestinal Diseases, Pp 1-11 (2020)
Background and Aims: KRP203 is a potent oral agonist of the sphingosine-1-phosphate receptor subtype 1 that induces the sequestration of peripheral lymphocytes, thereby potentially reducing the number of activated lymphocytes circulating to the gastr
Externí odkaz:
https://doaj.org/article/b2995644ed9f4c96bffe9657f67e3707
Autor:
Larisa Bora, Tobias Burkard, Martina Herrero San Juan, Heinfried H. Radeke, Ana Maria Muț, Lavinia Lia Vlaia, Ioana Zinuca Magyari-Pavel, Zorița Diaconeasa, Sonia Socaci, Florin Borcan, Brigitta Kis, Delia Muntean, Cristina Adriana Dehelean, Corina Danciu
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2413 (2022)
This study presents phytochemical characterization and biological evaluation of Origanum vulgare L. essential oil (OEO) formulated as polymeric micelles drug delivery systems as a possible non-invasive approach for the management of skin tags. GC-MS
Externí odkaz:
https://doaj.org/article/87cb56e197d74b99b7d0b6c8c85cf1dd
Autor:
Tobias Burkard, Caroline Dreis, Martina Herrero San Juan, Meik Huhn, Andreas Weigert, Josef M. Pfeilschifter, Heinfried H. Radeke
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment. Infiltrating regulatory T lymphocytes contribute to this immunosuppression by inhibiting prolif
Externí odkaz:
https://doaj.org/article/46a621db355d45be9764a551e7541c65
Autor:
Caroline Dreis, Florian M. Ottenlinger, Mateusz Putyrski, Andreas Ernst, Meik Huhn, Katrin G. Schmidt, Josef M. Pfeilschifter, Heinfried H. Radeke
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
IL-1 family member IL-33 exerts a variety of immune activating and regulating properties and has recently been proposed as a prognostic biomarker for cancer diseases, although its precise role in tumor immunity is unclear. Here we analyzed in vitro c
Externí odkaz:
https://doaj.org/article/067de208fbb649c2893b59fdf2b65deb
Autor:
Franziska Moll, Maria Walter, Flávia Rezende, Valeska Helfinger, Estefania Vasconez, Tiago De Oliveira, Florian R. Greten, Catherine Olesch, Andreas Weigert, Heinfried H. Radeke, Katrin Schröder
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
AimReactive oxygen species (ROS) produced by enzymes of the NADPH oxidase family serve as second messengers for cellular signaling. Processes such as differentiation and proliferation are regulated by NADPH oxidases. In the intestine, due to the exce
Externí odkaz:
https://doaj.org/article/147fd63112754e83979e52a016782146
Autor:
Katrin G. Schmidt, Martina Herrero San Juan, Sandra Trautmann, Lucija Berninger, Anja Schwiebs, Florian M. Ottenlinger, Dominique Thomas, Frank Zaucke, Josef M. Pfeilschifter, Heinfried H. Radeke
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Systemic sclerosis (SSc) is a rare multi-organ autoimmune disease characterized by progressive skin fibrosis. Inflammation, type 2 immunity, and fibrogenic processes are involved in disease development and may be affected by sphingolipids. However, d
Externí odkaz:
https://doaj.org/article/e8da4c3c7a9a49eabe1d5fe6bd9e0ca8
Autor:
Anja Schwiebs, Dominique Thomas, Burkhard Kleuser, Josef M. Pfeilschifter, Heinfried H. Radeke
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
A balanced sphingolipid rheostat is indispensable for dendritic cell function and survival and thus initiation of an immune response. Sphingolipid levels are dynamically maintained by the action of sphingolipid enzymes of which sphingosine kinases, S
Externí odkaz:
https://doaj.org/article/9de3ce7706394ce5b4720b72aa331417