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Autor:
Eric Francotte, Jan W. Priess, Claudio Valente, Dominik Rufle, Christophe Bury, Luigi La Vecchia, Heiner Schütz, J. Constanze D. Hartwieg
Publikováno v:
Organic Process Research & Development. 18:1120-1127
3,5-Disubstituted piperidines are versatile building blocks that find broad application in medicinal chemistry programs. Here we describe how all four diastereoisomers of a 5-aryl-substituted nipec...